Selected papers
| Roselló-Díez A, Ros MA,Torres M. Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivison. Science (2011) 332:1086-8 [http://www.sciencemag.org/] |
| Moreno-Loshuertos R, Ferrín G, Acín-Pérez R, Gallardo ME, Viscomi C, Pérez-Martos A, Zeviani M, Fernández-Silva P, Enríquez JA. Evolution Meets Disease: Penetrance and Functional Epistasis of Mitochondrial tRNA Mutations. Plos Genet (2011) 7:e1001379 |
| González-Rosa JM, Martín V, Peralta M, Torres M, Mercader N. Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish. Development (2011) 138:1663-74 |
| Del Monte G, Casanova JC, Guadix JA, Macgrogan D, Burch JB, Pérez-Pomares JM, de la Pompa JL. Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis. Circ Res (2011) 108:824-36 |
| Casanova JC, Uribe V, Badia-Careaga C, Giovinazzo G, Torres M, Sanz-Ezquerro JJ. Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements. Development (2011) 138:1195-205 |
| Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A, González MA. miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ (2011) 18:985-95 |
| Fernandez-Tresguerres B, Cañon S, Rayon T, Pernaute B, Crespo M, Torroja C, Manzanares M. Evolution of the mammalian embryonic pluripotency gene regulatory network. Proc Natl Acad Sci U S A (2010) 107:19955-60 |
| Luna-Zurita L, Prados B, Grego-Bessa J, Luxan G, del Monte G, Benguria A, Adams RH, Perez-Pomares JM, de la Pompa JL. Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J Clin Invest (2010) 120:3493-507 |
| Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA. An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell (2010) 19:207-19 |
| Carramolino L, Fuentes J, Garcia-Andres C, Azcoitia V, Riethmacher D, Torres M. Platelets Play an Essential Role in Separating the Blood and Lymphatic Vasculatures During Embryonic Angiogenesis. Circ Res (2010) 106:1197-201 |
The CDR department investigates the origin, differentiation and integration of cardiovascular cell lineages in chick, mouse and zebrafish models, using complementary experimental embryology, genetic and mass-screening approaches.
This focus is complemented by studies in classical models such as the limb primordium and mammalian blastocyst.
© 2012 Centro Nacional de Investigaciones Cardiovasculares