The aim of the Stem Cell Biology Program is to understand how the pluripotent state is achieved and maintained in embryonic and adult stem cells. By understanding the mechanisms and pathways that drive stem-cell differentiation we will be able to address the fundamental question of how cardiovascular and hematopoietic cell fates are established.
- Miguel Manzanares Fourcade
- Program Coordinator
- Ext.3109
Miguel Manzanares obtained his degree in Biology from the Universidad Autónoma de Madrid (UAM) in 1988, and his PhD from the same university in 1993. During his PhD studies in the group of Rafael Garesse (Department of Biochemistry, UAM), Miguel compared the genetic mechanisms of embryonic segmentation in crustaceans and insects. He subsequently worked for six years in Robb Krumlauf’s group at the National Institute of Medical Research in London, where he investigated the role of Hox genes in the patterning of the vertebrate nervous system, as well as studying the evolution of the neural crest. On his return to Madrid Miguel joined Angela Nieto’s group at the Instituto Cajal (CSIC), where he worked on the role of Snail genes in the patterning and evolution of the neural crest. In 2001 he established his own research group at the Instituto de Investigaciones Biomédicas (CSIC-UAM), devoted to the study of evolutionary novelties and the functional analysis of genome regulation and evolution. He was elected member of the EMBO-YIP programme in 2003, and joined the CNIC in 2007.
© 2012 Centro Nacional de Investigaciones Cardiovasculares