Figure: Imaging thrombo-inflammatory events in the circulation of live animals. Multichannel fluorescence intravital microscopy allows identification of leukocytes on inflamed venules (labeled with anti-L-selectin antibody, in blue). Leukocyte interaction with circulating platelets (labeled in red) induces the production of radical oxygen species (green intracellular spots), which can alter the integrity of the vasculature during acute inflammation. Arrow indicates the direction of blood flow. Bar = 10 µm.
Andres Hidalgo received his B.S. at the Universidad Autónoma de Madrid in 1993, and received his PhD in 1999 for his work in the control of adhesion in hematopoietic cells, in Dr. Joaquin Teixidó’s laboratory (CIB, Madrid). In 2000 he moved to New York, where he studied leukocyte and blood stem cell migration, as well as the inflammatory process, in Dr. Paul Frenette’s laboratory (Mount Sinai School of Medicine). In 2008, after obtaining a Ramón y Cajal reintegration fellowship, he joined the Department of Atherothrombosis and Cardiovascular Imaging at CNIC.