These projects, led by Dr. Valentín Fuster, are linked to the “HRP Initiative” and are longitudinal studies into the quantification of the progress of subclinical cardiovascular disease by ultrasound imaging.
CNIC Project 1 is a pilot study of a cohort of workers from the General Motors automobile assembly plant in Figueruelas (Zaragoza). The aim of the study is to evaluate the presence of subclinical atherosclerosis and its progression among 4500 young and middle-aged men and women, in order to obtain more precise prognostic information. The study is being conducted through collaboration with the Instituto Aragonés de Ciencias de la Salud.
CNIC Project
2 is a larger study designed to evaluate the presence
of subclinical atherosclerosis and its progression among
more than 6000 young and middle-aged (40 to 55 years)
working men and women from private companies.
The innovative characteristics of this project compared
with previous studies are the evaluation of a younger group
and its longitudinal design. The study will also provide
a systems biology approach, integrating evaluation by advanced
ultrasound, MRI, PET, and genomic, epigenomic and metabolomic
analyses.
CNIC Projects 1 and 2 involve contributions from scientists working at institutions in Spain (the CNIC, the Hospital Clínic in Barcelona, and the Hospital de La Princesa in Madrid) and the United States (Mount Sinai Hospital, Mount Sinai School of Medicine, Johns Hopkins University Bloomberg School of Public Health, and Tufts University).
At the CNIC, these projects involve the participation of the Department Epidemiology, Atherothrombosis and Imaging and the Translational Platform.
© 2012 Centro Nacional de Investigaciones Cardiovasculares