Home Excelencia Severo Ochoa
Selected papers
Tarin C, Lavin B, Gomez M, Saura M, Diez-Juan A, Zaragoza C. The extracellular matrix metalloproteinase inducer EMMPRIN is a target of nitric oxide in myocardial ischemia/reperfusion. Free Radic Biol Med (2011) 51:387-95
Zaragoza C, Gomez-Guerrero C, Martin-Ventura JL, Blanco-Colio L, Lavin B, Mallavia B, Tarin C, Mas S, Ortiz A and Egido J. Animal models of cardiovascular diseases. J Biomed Biotechnol (2011) 2011:497841
Klink A, Hyafil F, Rudd J, Faries P, Fuster V, Mallat Z, Meilhac O, Mulder WJ, Michel JB, Ramirez F, Storm G, Thompson R, Turnbull IC, Egido J, Martín-Ventura JL, Zaragoza C, Letourneur D, Fayad ZA. Diagnostic and therapeutic strategies for small abdominal aortic aneurysms. Nat Rev Cardiol (2011) 8:338-47
Zaragoza C, Ibanez B, Jimenez-Borreguero LJ, Schulz V, Fayad Z, Fuster V. Future Perspectives In Cardiovascular Imaging. Simultaneous PET/MRI Technology In Biomedical Research. Nat Rev Cardiol (cnic Edition) (2010) 7:7-10
Tello D, Tarin C, Ahicart P, Breton-Romero R, Lamas S, Martinez-Ruiz A. A. Proteomics (2009) 9:5359-70
Lizarbe TR, Tarin C, Gomez M, Lavin B, Aracil E, Orte LM, Zaragoza C. Nitric oxide induces the progression of abdominal aortic aneurysms through the matrix metalloproteinase inducer EMMPRIN. Am J Pathol (2009) 175:1421-30
Martinez-Miguel P, Raoch V, Zaragoza C, Valdivielso JM, Rodriguez-Puyol M, Rodriguez-Puyol D, Lopez-Ongil S. Endothelin-converting enzyme-1 increases in atherosclerotic mice: potential role of oxidized low density lipoproteins. J Lipid Res (2009) 50:364-75
Tarin C, Gomez M, Calvo E, Lopez JA, Zaragoza C. Endothelial nitric oxide deficiency reduces MMP-13-mediated cleavage of ICAM-1 in vascular endothelium: a role in atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 29:27-32
Lizarbe TR, García-Rama C, Tarín C, Saura M, Calvo E, López JA, López-Otín C, Folgueras AR, Lamas S, Zaragoza C. Nitric oxide elicits functional MMP-13 protein-tyrosine nitration during wound repair. Faseb J (2008) 22:3207-15
Genís L, Gonzalo P, Tutor AS, Gálvez BG, Martínez-Ruiz A, Zaragoza C, Lamas S, Tryggvason K, Apte SS, Arroyo AG. Functional interplay between endothelial nitric oxide synthase and membrane type 1 matrix metalloproteinase in migrating endothelial cells. Blood (2007) 110:2916-23
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Carlos Zaragoza
  • Carlos Zaragoza Sánchez
  • Junior group leader
  • Ext.3308

Carlos Zaragoza received in 1990 his B.S. at the University Complutense of Madrid, Spain. In 1996 at the Department of Genetics, he received his PhD for his contribution in study of genetic mutations caused by the activation of mobile genetic elements. In 1995 Dr. Zaragoza moved to the Centro de Investigaciones Biológicas (CIB, CSIC, Madrid) where he started to work in an emerging field of research, in the laboratory of Dr. Santiago Lamas, characterizing the controlling region of the gene, which encodes for the inducible Nitric Oxide Synthase, to address the effect of Nitric Oxide (NO) in the inflammatory response. In 1996 as postdoctoral fellow in the laboratory of Dr. Charles J. Lowenstein, at the Division of Cardiology of the Johns Hopkins School of Medicine, he studied the relevance of NO in the in the host defense against viral pathogens in cardiovascular pathology, in particular during Coxsackievirus-mediated myocarditis. Back in 2002 Dr. Zaragoza joined the CNIC with a Ramon y Cajal reintegration contract to start a research career in the field of Cardiology in Spain, where he is now junior scientist running the laboratory of Animal Models of Cardiovascular Pathology in the Department of Atherotrombosis and Cardiovascular Imaging leaded by Dr. Valentin Fuster.