The Microscopy Unit provides state-of-the-art optical and fluorescence microscopy technologies to CNIC scientists. Several bright field, wide field, confocal and multiphoton microscopes are available for multicolor immunofluorescence imaging and for a variety of live-cell and in-tissue studies (EQUIPMENT).
The Unit develops customized applications including very large image tiling and stitching, cell tracking, shape recognition, 3D/4D-multicolor rendering and co-localization.
More advanced applications are employed to study protein mobility, protein-protein interaction, membrane fluidity and in-vivo cellular dynamics (GALLERY). These applications are also available to external scientists (HOW TO BOOK).
Resources are also maintained for biochemistry, cell/tissue culture and data analysis.
The Unit is strongly committed to technological innovation and the development of new imaging applications. Research projects range from in vitro studies (function of biomolecules) to tracking biological processes in living cells, model organisms and tissues. Our main areas of interest are membrane receptors involved in cell adhesion, migration mechanisms, receptor microdomain dynamics and protein-lipid interactions.
The Unit actively disseminates its expertise in fluorescence spectroscopy and microscopy principles, instrumentation, and applications to the scientific community. This is achieved through our international workshops in the field of fluorescence microscopy and by publishing our findings in peer-reviewed journals, books and conferences. This website is one of the Unit's central resources through which we keep the community updated about our activities (TRAINING).
Non-registered CNIC researchers and researchers from outside the CNIC who are interested in using the Unit's resources should follow the procedures for contacting the Unit staff in the HOW TO BOOK SECTION.