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SRSF3 expression in adult cardiomyocytes. Pink staining shows SRSF3 expression in cell nuclei, which are stained blue. Green staining shows the presence of troponin, a sarcomere protein expressed in cardiomyocytes.
Research
4 Jul 2019

A new study published in Circulation Research shows that loss of cardiac expression of SRSF3 leads to a critical reduction in the expression of genes related to contraction

About the CNIC
23 Apr 2018

The project is coordinated by Dr. José Antonio Enríquez and will receive funding worth $1350000 (€1.100.062) over the next 3 years

De izda. a dcha.: José Antonio Enriquez, María del Mar Muñoz, Fátima Sánchez-Cabo, Luis Jesús Jiménez-Borreguero, Rocío Nieto-Arellano, Andrés González-Guerra, Carlos Torroja, José María Castellanos, y Concepción Jiménez.
Research
3 Apr 2018

The study is published in Science Translational Medicine and was conducted by researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)

Jesús Vázquez, María Villalba, Sara Cogliati, Marina López, Paula Ortiz, José Antonio Enriquez, Laura Padrón, Elena Bonzón y Enrique Lara.
Research
6 Feb 2018

The calcineurin variant CnAβ1 redirects glucose metabolism to increase production of antioxidant compounds, reducing cardiac hypertrophy and improving heart function