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Research
17 Sep 2020

The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes

Research
16 Sep 2020

The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart

Research
4 Jun 2020

Published in Science Advances, the study shows that malfunctioning of this system leads to congenital deformities

Experimental design of the study and summary of the results obtained
Research
21 Apr 2020

The study, published today in JACC, shows that activation of the complement system is one of the most characteristic molecular changes taking place in the early stages of the development of atherosclerotic plaques


Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
Research
3 Apr 2020

Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR

Andrés Hidalgo, Jose María Adrover y Alejandra Aroca
Research
14 Jan 2020

The newly identified immune control system is located within one of the most important cell types of the immune system, the neutrophil


Dr. José María Mendiguren, Director de Servicios Médicos de Banco Santander, Leticia Fernández-Friera, cardióloga del CNIC y del Hospital Universitario HM Montepríncipe, y Dr. Valentín Fuster, Director del CNIC.
Research
26 Mar 2019

The results, published in JACC, demonstrate the potential of this technology to generate images of the inflammation associated with systemic atherosclerosis; this information will be useful for the study of early stages of this disease and will help to identify individuals who will benefit from early medical intervention

Andrés Hidalgo y José María Adrover+
Research
30 Jan 2019

Neutrophils are the body’s main line of defense, but their action can also damage healthy cells in the cardiovascular system

Annalaura Mastrangelo, David Sancho, Salvado Iborra, María Martínez-López y Ruth Conde Garrosa.
Research
30 Jan 2019

The study, published in Immunity, shows that some intestinal bacteria, such as Lactobacillus, strengthen the intestinal barrier by interacting with an immune cell receptor called Mincle (Clec4e)

From left to right: David Sancho, Carlos del Fresno, Paula Saz, and Sarai Martínez Cano.
Research
19 Oct 2018

CNIC researchers have discovered a new inflammatory control mechanism that paves the way to controlling injury generated during the immune response