Antibodies for the treatment of infections, tumor metastasis and Alzheimer disease.
The present invention refers to the field of medicine and immunology. Specifically it relates to inhibitors of a matrix metalloproteinase (MMP) for use in the prophylactic and/or therapeutic treatment of diseases benefiting from an increase in the activity of patrolling monocytes (PMo), such as infections (e.g. L. monocytogenes infection), neurological diseases (e.g. Alzheimer’s disease) and cancer. It further relates to said MMP inhibitors binding to particular amino acid sequences and epitopes within the MMP.NumberEP17382735.3Priority date03/11/2017AplicantsCNICInventorsAlicia García Arroyo, Cristina clemente Toribio, Fernando Martínez Benito, Rubén Avelino Mota