Resultados de la búsqueda

Tena JJ, Alonso ME, de la Calle-Mustienes E, Splinter E, de Laat W, Manzanares M, Gómez-Skarmeta JL. An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation. Nat Commun (2011) 2:310

Pernaute B, Spruce T, Rodriguez TA, Manzanares M. MiRNA-mediated regulation of cell signaling and homeostasis in the early mouse embryo. Cell Cycle (2011) 10:584-91

Cañon S*, Fernandez-Tresguerres B*, Manzanares M (SC and BFT contributed equally) Pluripotency and lineages in the mammalian blastocyst: An evolutionary view. Cell Cycle (2011) 10:1731-8

Spruce T*, Pernaute B*, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M*, Rodriguez TA* (TS and BP contributed equally. MM and TAR co-corresponding authors) An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell (2010) 19:207-19

Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes Ø, Engström PG, Alonso ME, Mustienes Ede L, Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, Argenton F, Lenhard B, Becker TS. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proc Natl Acad Sci U S A (2010) 107:778-80

Fernandez-Tresguerres B*, Cañon S*, Rayon T, Pernaute B, Crespo M, Torroja C, Manzanares M (BFT and SC contributed equally) Evolution of the mammalian embryonic pluripotency gene regulatory network Proc Natl Acad Sci U S A (2010) 107:19955-60

Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME, de la Calle-Mustienes E, Smeenk L, Rinne T, Parsaulian L, Bolat E, Jurgelenaite R, Huynen MA, Hoischen A, Veltman JA, Brunner HG, Roscioli T, Oates E, Wilson M, Manzanares M, Gómez-Skarmeta JL, Stunnenberg HG, Lohrum M, van Bokhoven H, Zhou H. Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus. PLoS Genet (2010) 6:e1001065

Pittman AM, Naranjo S, Jalava SE, Twiss P, Ma Y, Olver B, Lloyd A, Vijayakrishnan Y, Qureshi M, Broderick P, van Wezel T, Morreau H, Tuupanen S, Aaltonen LA, Alonso ME, Manzanares M, Gavilan A, Visakorpi T, Gomez-Skarmeta JL, Houlston RS. Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H. PLoS Genet (2010) 6:e1001126

Pernaute B, Canon S, Crespo M, Fernandez-Tresguerres B, Rayon T, Manzanares M. Comparison of extraembryonic expression of Eomes and Cdx2 in pregastrulation chick and mouse embryo unveils regulatory changes along evolution Dev Dyn (2010) 239:620-9

Alonso ME, Pernaute B, Crespo M, Gomez-Skarmeta JL, Manzanares M. Understanding the regulatory genome. Int J Dev Biol (2009) 53:1367-78