Metoprolol for critical COVID-19 patients

Metoprolol for critical COVID-19 patients

The most serious manifestation of COVID-19 is severe respiratory failure that requires intubation and is associated with high mortality. SARS-CoV-2 lung infection can lead to the development of acute respiratory distress syndrome (ARDS), in which neutrophil inflammation/hyperactivation plays a central role. Currently...
Improving a vaccine with SARS-CoV-2 antigens

Improving a vaccine with SARS-CoV-2 antigens

The response against the COVID-19 pandemic caused by the SARS-CoV-2 coronavirus infection is forcing science to sap its resources as quickly as possible to develop effective vaccines. In Spain, Professor Mariano Esteban and Juan García Arriaza at the National Center for Biotechnology (CNB-CSIC)...
Development of trials for the detection of antibodies against SARS-COV-2 in serum

Development of trials for the detection of antibodies against SARS-COV-2 in serum

To develop and validate new diagnostic tests for antibodies against coronavirus with proven and improved sensitivity and specificity. That is the project which the CNIC group led by Dr. Miguel Torres is working on, in collaboration with other groups at the center, such as Dr. Jorge Alegre’s and Dr. María Montoya’s groups, as well as with Dr. Óscar Llorca of the CNIO...
Research on the interaction of SARS-CoV-2 and the host at the proteomic level

Research on the interaction of SARS-CoV-2 and the host at the proteomic level

One year after the first documented cases of SARS-CoV-2 infection, current knowledge about its pathogenesis still remains limited, so therapies for severe cases are mostly speculative. The pandemic, says Jesús Vázquez, has shown that there is an “urgent need for technologies that can accelerate our understanding of this type of new infectious diseases"...

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