Publicaciones seleccionadas

Cibrian D, Saiz ML, de la Fuente H, Sanchez-Diaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vazquez J, Punzon C, Fresno M, Vicente-Manzanares M, Dauden E, Fernandez-Salguero PM, Martin P, Sanchez-Madrid F. CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis. Nat Immunol (2016) 17:985-96
Blas-Rus N, Bustos-Moran E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, Jorge I, Vazquez J, Alarcon B, Malumbres M, Martin-Cofreces NB, Sanchez-Madrid F. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun (2016) 7:11389
Link to the full text in Repisalud
Villarroya-Beltri C, Baixauli F, Mittelbrunn M, Fernández-Delgado I, Torralba D, Moreno-Gonzalo O, Baldanta S, Enrich C, Guerra S, Sánchez-Madrid F. ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins Nat Commun (2016) 7:13588
Link to the full text in Repisalud
Nunez-Andrade N, Iborra S, Trullo A, Moreno-Gonzalo O, Calvo E, Catalan E, Menasche G, Sancho D, Vazquez J, Yao TP, Martin-Cofreces NB*, Sanchez-Madrid F*. (NBMC and FSM contributed equally) HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes. J Cell Sci (2016) 129:1305-11
Barreiro O, Cibrian D, Clemente C, Alvarez D, Moreno V, Valiente I, Bernad A, Vestweber D, Arroyo AG, Martin P, Andrian UV, Sanchez Madrid F. Pivotal role for skin trans-endothelial radio-resistant anti-inflammatory macrophages in tissue repair. eLife (2016) 5:e15251
Link to the full text in Repisalud
Martinez Del Hoyo G, Ramirez-Huesca M, Levy S, Boucheix C, Rubinstein E, Minguito de la Escalera M, Gonzalez-Cintado L, Ardavin C, Veiga E, Yanez-Mo M, Sanchez-Madrid F CD81 Controls Immunity to Listeria Infection through Rac-Dependent Inhibition of Proinflammatory Mediator Release and Activation of Cytotoxic T Cells. J Immunol (2015) 194:6090-101
Mittelbrunn M, Vicente-Manzanares M, Sanchez-Madrid F Organizing polarized delivery of exosomes at synapses Traffic (2015) 16:327-37
Martín-Cófreces NB, Baixauli F, Sánchez-Madrid F. Immune synapse: conductor of orchestrated organelle movement. Trends Cell Biol (2014) 24:61-72
Rocha-Perugini V, Gordon-Alonso M and Sanchez-Madrid F. PIP: choreographer of actin-adaptor proteins in the HIV-1 dance. Trends Microbiol (2014) 22:379-88
Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado JM, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano CO, Veiga E, Martin-Cofreces NB and Sanchez-Madrid F. Miro-1 links mitochondria and microtubule dynein motors to control lymphocyte migration and polarity. Mol Cell Biol (2014) 34:1412-26
de la Fuente H, Cruz-Adalia A, Martinez Del Hoyo G, Cibrian-Vera D, Bonay P, Perez-Hernandez D, Vazquez J, Navarro P, Gutierrez-Gallego R, Ramirez-Huesca M, Martin P and Sanchez-Madrid F The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with Galectin-1. Mol Cell Biol (2014) 34:2479-87
Rocha-Perugini V, Gonzalez-Granado JM, Tejera E, Lopez-Martin S, Yanez-Mo M and Sanchez-Madrid F. Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling. Eur J Immunol (2014) 44:1967-75
Gutiérrez-Vázquez C*, Villarroya-Beltri C*, Mittelbrunn M, Sánchez-Madrid F (CGV and CVB contributed equally) Transfer of extracellular vesicles during immune cell-cell interactions. Immunol Rev (2013) 251:125-42
Villarroya-Beltri C, Gutiérrez-Vázquez C, Sánchez-Cabo F, Pérez-Hernández D, Vázquez J, Martin-Cofreces N, Martinez-Herrera DJ, Pascual-Montano A, Mittelbrunn M*, Sánchez-Madrid F* (MM and FSM contributed equally) Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat Commun (2013) 4:2980
Link to the full text in Repisalud
Rocha-Perugini V, Zamai M, González-Granado J, Barreiro O, Tejera E, Yañez-Mó M, Caiolfa V, Sanchez-Madrid F. CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 33:3644-58
Mittelbrunn M, Sánchez-Madrid F. Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol (2012) 13:328-35
Martín-Cófreces NB, Baixauli F, López MJ, Gil D, Monjas A, Alarcón B, Sánchez-Madrid F. End-binding protein 1 controls signal propagation from the T cell receptor. EMBO J (2012) 31:4140-52
de la Fuente H, Perez-Gala S, Bonay P, Cruz-Adalia A, Cibrian D, Sanchez-Cuellar S, Dauden E, Fresno M, García-Diez A, Sanchez-Madrid F. Psoriasis in humans is associated with downregulation of galectins in dendritic cells. J Pathol (2012) 228:193-203
Baixauli F, Martín-Cófreces NB, Morlino G, Carrasco YR, Calabia-Linares C, Veiga E, Serrador JM, Sánchez-Madrid F. The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse. EMBO J (2011) 30:1238-50
Mittelbrunn M*, Gutiérrez-Vázquez C*, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F (MM and CGV contributed equally) Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells Nat Commun (2011) 2:282