Publicaciones seleccionadas

Cibrian D, Saiz ML, de la Fuente H, Sanchez-Diaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vazquez J, Punzon C, Fresno M, Vicente-Manzanares M, Dauden E, Fernandez-Salguero PM, Martin P, Sanchez-Madrid F. CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis. Nat Immunol (2016) 17:985-96
Blas-Rus N, Bustos-Moran E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, Jorge I, Vazquez J, Alarcon B, Malumbres M, Martin-Cofreces NB, Sanchez-Madrid F. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun (2016) 7:11389
Link to the full text in Repisalud
Villarroya-Beltri C, Baixauli F, Mittelbrunn M, Fernández-Delgado I, Torralba D, Moreno-Gonzalo O, Baldanta S, Enrich C, Guerra S, Sánchez-Madrid F. ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins Nat Commun (2016) 7:13588
Link to the full text in Repisalud
Barreiro O, Cibrian D, Clemente C, Alvarez D, Moreno V, Valiente I, Bernad A, Vestweber D, Arroyo AG, Martin P, Andrian UV, Sanchez Madrid F. Pivotal role for skin trans-endothelial radio-resistant anti-inflammatory macrophages in tissue repair. eLife (2016) 5:e15251
Link to the full text in Repisalud
Nunez-Andrade N, Iborra S, Trullo A, Moreno-Gonzalo O, Calvo E, Catalan E, Menasche G, Sancho D, Vazquez J, Yao TP, Martin-Cofreces NB*, Sanchez-Madrid F*. (NBMC and FSM contributed equally) HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes. J Cell Sci (2016) 129:1305-11
Martinez Del Hoyo G, Ramirez-Huesca M, Levy S, Boucheix C, Rubinstein E, Minguito de la Escalera M, Gonzalez-Cintado L, Ardavin C, Veiga E, Yanez-Mo M, Sanchez-Madrid F CD81 Controls Immunity to Listeria Infection through Rac-Dependent Inhibition of Proinflammatory Mediator Release and Activation of Cytotoxic T Cells. J Immunol (2015) 194:6090-101
Mittelbrunn M, Vicente-Manzanares M, Sanchez-Madrid F Organizing polarized delivery of exosomes at synapses Traffic (2015) 16:327-37
Martín-Cófreces NB, Baixauli F, Sánchez-Madrid F. Immune synapse: conductor of orchestrated organelle movement. Trends Cell Biol (2014) 24:61-72
Rocha-Perugini V, Gordon-Alonso M and Sanchez-Madrid F. PIP: choreographer of actin-adaptor proteins in the HIV-1 dance. Trends Microbiol (2014) 22:379-88
Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado JM, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano CO, Veiga E, Martin-Cofreces NB and Sanchez-Madrid F. Miro-1 links mitochondria and microtubule dynein motors to control lymphocyte migration and polarity. Mol Cell Biol (2014) 34:1412-26
de la Fuente H, Cruz-Adalia A, Martinez Del Hoyo G, Cibrian-Vera D, Bonay P, Perez-Hernandez D, Vazquez J, Navarro P, Gutierrez-Gallego R, Ramirez-Huesca M, Martin P and Sanchez-Madrid F The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with Galectin-1. Mol Cell Biol (2014) 34:2479-87
Rocha-Perugini V, Gonzalez-Granado JM, Tejera E, Lopez-Martin S, Yanez-Mo M and Sanchez-Madrid F. Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling. Eur J Immunol (2014) 44:1967-75
Gutiérrez-Vázquez C*, Villarroya-Beltri C*, Mittelbrunn M, Sánchez-Madrid F (CGV and CVB contributed equally) Transfer of extracellular vesicles during immune cell-cell interactions. Immunol Rev (2013) 251:125-42
Villarroya-Beltri C, Gutiérrez-Vázquez C, Sánchez-Cabo F, Pérez-Hernández D, Vázquez J, Martin-Cofreces N, Martinez-Herrera DJ, Pascual-Montano A, Mittelbrunn M*, Sánchez-Madrid F* (MM and FSM contributed equally) Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat Commun (2013) 4:2980
Link to the full text in Repisalud
Rocha-Perugini V, Zamai M, González-Granado J, Barreiro O, Tejera E, Yañez-Mó M, Caiolfa V, Sanchez-Madrid F. CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 33:3644-58
Mittelbrunn M, Sánchez-Madrid F. Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol (2012) 13:328-35
Martín-Cófreces NB, Baixauli F, López MJ, Gil D, Monjas A, Alarcón B, Sánchez-Madrid F. End-binding protein 1 controls signal propagation from the T cell receptor. EMBO J (2012) 31:4140-52
de la Fuente H, Perez-Gala S, Bonay P, Cruz-Adalia A, Cibrian D, Sanchez-Cuellar S, Dauden E, Fresno M, García-Diez A, Sanchez-Madrid F. Psoriasis in humans is associated with downregulation of galectins in dendritic cells. J Pathol (2012) 228:193-203
Baixauli F, Martín-Cófreces NB, Morlino G, Carrasco YR, Calabia-Linares C, Veiga E, Serrador JM, Sánchez-Madrid F. The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse. EMBO J (2011) 30:1238-50
Mittelbrunn M*, Gutiérrez-Vázquez C*, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F (MM and CGV contributed equally) Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells Nat Commun (2011) 2:282