Ext. 2021
Jorge Alegre-Cebollada

Somos un equipo científico multidisciplinar que emplea la bioquímica, la biofísica y las técnicas de molécula individual para comprender la mecánica del tejido cardiaco y su regulación en salud y enfermedad.

Ext. 1502
Vicente Andrés García

La Organización Mundial de la Salud ha estimado que las enfermedades cardiovasculares serán en el año 2020 el principal problema sanitario y socio-económico en todo el mundo, en parte debido al envejecimiento progresivo que la población mundial está experimentando.

Ext. 3115
Rui Benedito

Blood and lymphatic vessels are not simply conduits for the body’s fluids; they also control essential biological responses and are an important therapeutic target in cancer and cardiovascular diseases.

Ext. 2012
Jacob Fog Bentzon

Los infartos y muchos casos de ictus isquémicos son provocados por la aterosclerosis, una enfermedad extremadamente extendida que ataca las arterias de personas de todo el mundo.

Ext. 3307
Juan A Bernal Rodríguez

Our research into cardiovascular disease is based on a simple principle: create to understand, create to treat.

Ext. 4110
Héctor José Bueno Zamora

The group has a strong connection with clinical research in different fields including atherosclerosis, acute coronary syndromes, acute and chronic heart failure, pulmonary hypertension, cardiovascular ageing and frailty, valve heart disease, advanced cardiovascular imaging, genetic and familial CV diseases.

Ext. 3110
José Luis de la Pompa Mínguez

We are interested in the molecular mechanisms that regulate cardiovascular development, homeostasis and disease. Most of our effort centers on the study of the Notch pathway.

Ext. 1158
Miguel Ángel del Pozo Barriuso

Signals are the language of life, mediating the communication essential for cells’ proper behavior.

Ext. 2309
José Antonio Enríquez Domínguez

Our laboratory researches the mammalian mitochondrial electron transport chain (MtETC) and H+-ATP synthase, which together constitute the oxidative phosphorylation (OXPHOS) system.

Ext. 1510
David Filgueiras Rama

El laboratorio se centra en el abordaje multidisciplinar de los mecanismos que subyacen las arritmias cardíacas derivadas de enfermedades cardiovasculares con alta prevalencia en la población general, así como en poblaciones concretas con alto riesgo de muerte súbita.

Ext. 4260
Valentín Fuster Carulla

Investigators Valentín Fuster, Javier Sanz (CNIC, Icahn School of Medicine at Mount Sinai), José María Castellano (CNIC, Hospital Universitario HM Monte Príncipe), Antonio Fernández-Ortíz (CNIC, Hospital Clínico San Carlos), Leticia Fernández Friera (CNIC, Hospital Universitario HM Monte Príncipe), Beatriz López-Melgar (CNIC, Hospital Universitario HM Puerta del Sur), Inés Garc

Ext. 1159
Alicia García Arroyo

Angiogenesis, the formation of new capillaries, is closely linked to inflammation.

Ext. 1504
Andrés Hidalgo Alonso

Our laboratory is interested in innate immune cells. Macrophages, a major cellular component of innate immunity, are conspicuously present in most organs in which they are endowed with specialized phenotypes and functions that support normal tissue integrity. How they acquire these properties in certain organs, like the heart, is unknown.

Ext. 4302
Borja Ibáñez Cabeza

Our laboratory focuses on the study of myocardial diseases, ranging from ischemia/reperfusion to heart failure. Our studies span the molecular origins of disease and their manifestations at the macro-anatomical and physiological levels, and our group includes experts in molecular biology, clinical cardiology and cardiovascular imaging.

Ext. 1512
José Jalife

El laboratorio de arritmias cardíacas, con José Jalife al frente, se ha incorporado al CNIC en septiembre de 2014.

Ext. 3309
Enrique Lara Pezzi

Our lab studies the molecular mechanisms that regulate cardiac development and heart disease. One of our main interests is the role of alternative splicing (AS) in these processes.

Ext. 3109
Miguel Manzanares Fourcade

How the genome is co-ordinately regulated during development is one of the major unanswered questions in modern biology.

Ext. 2009
Pilar Martin

Understanding peripheral mechanisms operating in autoinmmune and chronic inflammatory diseases is critical for the design and development of novel therapies against these immunological disorders.

Ext. 3117
Nadia Mercader Huber

El epicardio es una capa epitelial unicelular que recubre el miocardio. Se desarrolla a partir del proepicardio (PE), un grupo de células que se forman en el tracto de entrada del tubo cardiaco.

Ext. 4310
Pura Muñoz Cánoves

Our group aims to understand the cellular and molecular mechanisms regulating striated muscle regeneration and growth in physiology and pathology, as well as in aging.

Ext. 4120
Silvia Priori

La muerte súbita cardíaca (MSC) es una de las principales causas de mortalidad en los países occidentales. Por edades, en las personas mayores la enfermedad coronaria arterial es la mayor causante de la MSC, mientras que en individuos jóvenes la causa principal de la MSC son las enfermedades arritmogénicas hereditarias.

Ext. 2020
Almudena Ramiro

B lymphocytes are key players of the immune response, mostly through the generation of a hugely diverse repertoire of protective antibodies.

Ext. 1150
Juan Miguel Redondo Moya

Many important biological processes, including the regulation and development of the immune and cardiovascular systems, are regulated by the calcineurin (CN)/NFAT pathway. Much of our previous work relates to molecular interactions of CN with substrates. We are now studying the regulation and function of this pathway in inflammation, cardiovascular and inflammatory diseases.

Ext. 3306
Mercedes Ricote Pacheco

Nuclear hormone receptors constitute a superfamily of ligandactivated transcription factors with diverse roles in development and homeostasis.

Ext. 2004
Guadalupe Sabio Buzo

Metabolic syndrome is a medical disorder defined by the co-occurrence of obesity, impaired glucose tolerance, dyslipidemia and hypertension.

Ext. 2000
Francisco Sánchez Madrid

Intercellular communication is fundamental to the innate and adaptive immune responses.

Ext. 2010
David Sancho Madrid

Las células dendríticas (DCs) son centinelas de nuestro sistema inmunológico que inician y modulan la inmunidad o la tolerancia. La manipulación de las DCs es una herramienta prometedora para el tratamiento de muchas enfermedades que tienen un componente inmunológico, incluyendo las enfermedades infecciosas, enfermedades cardiovasculares, enfermedades autoinmunes o cáncer.

Ext. 3311
Miguel Torres

We are interested in understanding the cellular basis of developmental processes and how this is controlled by transcription factor networks (TFN). We have developed genetic methods in the mouse that allow us to trace cell lineages using clonal analysis or functional mosaics.

Ext. 3324
Jesús María Vázquez Cobos

Our group works on the development of high-throughput quantitative approaches for the dynamic analysis of the deep proteome, which are being applied to basic and translational projects in the cardiovascular field.