Proteómica cardiovascular

Dr. Jesús Vázquez graduated in Physical Chemistry at the Universidad Complutense (Madrid, 1982) and carried out his PhD in Biochemistry at the Universidad Autónoma (Madrid, 1986), both with Special Distinction. During his postdoctoral training in USA and at the Centro de Biología Molecular Severo Ochoa (Madrid), he specialized in protein chemistry and in the study of biomembranes in the context of neurochemical diseases. Since then, he has played a pioneering role in the development of protein chemistry, mass spectrometry and proteomics in Spain. His laboratory has made relevant contributions to the field addressing subjects such as peptide fragmentation mechanisms, de novo peptide sequencing, advanced algorithms for high-throughput identification and quantification of proteins and post-translational modifications and systems biology analysis. The group has worked in mitochondrial proteomics, the mechanism of complex and supercomplex assembly and the molecular events taking place in the heart after infarction, including the impact on postranslational modifications The group has also developed a translational proteomics and metabolomics platform tfor the study of molecular mechanism and for the search for protein, metabolic and lipid factors associated to subclinical atherosclerosis and other diseases related to vascular remodelling. J. Vázquez is Profesor de Investigación of the CSIC and author of more than 210 international publicatons (H-index 48). He joined the CNIC as a Full Professor in 2011, where he leads the Cardiovascular Proteomics laboratory and the Proteomics Unit.