Publicaciones seleccionadas

Bravo-Cordero JJ, Cordani M, Soriano SF, Diez B, Munoz-Agudo C, Casanova-Acebes M, Boullosa C, Guadamillas MC, Ezkurdia I, Gonzalez-Pisano D, Del Pozo MA, Montoya MC. A novel high content analysis tool reveals Rab8-driven actin and FA reorganization through Rho GTPases and calpain/MT1. J Cell Sci (2016) 129:1734-49
Sala-Vila A*, Navarro-Lerida I*, Sanchez-Alvarez M, Bosch M, Calvo C, Lopez JA, Calvo E, Ferguson C, Giacomello M, Serafini A, Scorrano L, Enriquez JA, Balsinde J, Parton RG, Vazquez J, Pol A, Del Pozo MA. (*ASV and INL contributed equally) Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice. Sci Rep (2016) 6:27351
Navarro-Lérida I, Pellinen T, Sánchez SA, Guadamillas MC, Wang Y, Mirtti T, Calvo, Del Pozo MA. Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion Dev Cell (2015) 32:318-334
Shi Y, Tan SH, Ng S, Zhou J, Yang ND, Khoo GB, McMahon KA, Parton RG, Hill MM, Del Pozo MA, Kim YS, Shen HM Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy. Autophagy (2015) 11:769-84
Kosmalska AJ, Casares L, Elosegui-Artola A, Thottacherry JJ, Moreno-Vicente R, Gonzalez-Tarrago V, Del Pozo MA, Mayor S, Arroyo M, Navajas D, Trepat X, Gauthier NC, Roca-Cusachs P. Physical principles of membrane remodelling during cell mechanoadaptation. Nat Commun (2015) 6:7292
Echarri A, Del Pozo MA. Caveolae - mechanosensitive membrane invaginations linked to actin filaments. J Cell Sci (2015) 128:2747-58
Strippoli R, Loureiro J, Moreno V, Benedicto I, Perez Lozano ML, Barreiro O, Pellinen T, Minguet S, Foronda M, Osteso MT, Calvo E, Vazquez J, Lopez Cabrera M, Del Pozo MA Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis EMBO Mol Med (2015) 7:102-23
Parton RG, Del Pozo MA. Caveolae as plasma membrane sensors, protectors and organizers. Nat Rev Mol Cell Biol (2013) 14:98-112
Navarro-Lérida I, Sánchez-Perales S, Calvo M, Rentero C, Zheng Y, Enrich C, Del Pozo MA. A palmitoylation switch mechanism regulates Rac1 function and membrane organization. EMBO J (2012) 31:534-51
Echarri A, Del Pozo MA. Caveolae Curr Biol (2012) 22:R114-6
Echarri A, Muriel O, Pavón DM, Azegrouz H, Escolar F, Terrón MC, Sanchez-Cabo F, Martínez F, Montoya MC, Llorca O, Del Pozo MA. Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1 J Cell Sci (2012) 125:3097-113
Goetz JG*, Minguet S*, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA (JGG and SM contributed equally) Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis Cell (2011) 146:148-63
Castro-Castro A, Ojeda V, Barreira M, Sauzeau V, Navarro-Lérida I, Muriel O, Couceiro JR, Pimentel-Muíños FX, Del Pozo MA, Bustelo XR. Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation. EMBO J (2011) 30:3913-27
Guadamillas MC*, Cerezo A*, Del Pozo MA (MCG and AC contributed equally) Overcoming anoikis - pathways to anchorage-independent growth in cancer. J Cell Sci (2011) 124:3189-97
Muriel O, Echarri A, Hellriegel C, Pavón DM, Beccari L, Del Pozo MA. Phosphorylated filamin A regulates actin-linked caveolae dynamics. J Cell Sci (2011) 124:2763-76
Gonzalo P, Guadamillas MC, Hernandez-Riquer MV, Pollan A, Grande-Garcia A, Bartolome RA, Vasanji A, Ambrogio C, Chiarle R, Teixido J, Risteli J, Apte SS, del Pozo MA, Garcia-Arroyo A. MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling Dev Cell (2010) 18:77-89
Strippoli R, Benedicto I, Foronda M, Perez-Lozano ML, Sánchez-Perales S, López-Cabrera M, Del Pozo MA. p38 maintains E-cadherin expression by modulating TAK1-NF-{kappa}B during epithelial-to-mesenchymal transition. J Cell Sci (2010) 123:4321-31
Cerezo A*, Guadamillas MC*, Goetz JG, Sanchez-Perales S, Klein E, Assoian RK, del Pozo MA (AC and MCG contributed equally) The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism. Mol Cell Biol (2009) 29:5046-59
Strippoli R, Benedicto I, Pérez Lozano ML, Cerezo A, López-Cabrera M, del Pozo MA. Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway. Dis Model Mech (2008) 1:264-74
Del Pozo MA, Schwartz MA. Rac, membrane heterogeneity, caveolin and regulation of growth by integrins. Trends Cell Biol (2007) 17:246-50
Grande-García A, Echarri A, de Rooij J, Alderson NB, Waterman-Storer CM, Valdivielso JM, del Pozo MA. Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. J Cell Biol (2007) 177:683-94
del Pozo MA, Balasubramanian N, Alderson NB, Kiosses WB, Grande-García A, Anderson RG, Schwartz MA. Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nat Cell Biol (2005) 7:901-8
del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA. Integrins regulate Rac targeting by internalization of membrane domains. Science (2004) 303:839-42
del Pozo MA, Schwartz MA, Hu J, Kiosses WB, Altman A, Villalba M. Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading. J Immunol (2003) 170:41-7
Del Pozo MA, Kiosses WB, Alderson NB, Meller N, Hahn KM, Schwartz MA. Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. Nat Cell Biol (2002) 4:232-9