Publicaciones seleccionadas

    Hernansanz-Agustín P, Enríquez JA Functional segmentation of CoQ and cyt c pools by respiratory complex superassembly Free Radic Biol Med (2021) 167:232-242
    Cogliati S, Cabrera-Alarcón JL, Enriquez JA Regulation and functional role of the electron transport chain supercomplexes. Biochem Soc Trans (2021) 49:2655-2668
    Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, Tello D, Acín-Pérez R, Rodríguez-Aguilera JC, Navas P, Cogolludo Á, López-Montero I, Martínez-Del-Pozo Á, Egea J, López MG, Elrod JW, Ruíz-Cabello J, Bogdanova A, Enríquez JA, Martínez-Ruiz A Na(+) controls hypoxic signalling by the mitochondrial respiratory chain Nature (2020) 586:287-291
    Nicolas-Avila JA, Lechuga-Vieco AV, Esteban-Martinez L, Sanchez-Diaz M, Diaz-Garcia E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martinez-de-Mena R, Castejon-Vega B, Pun-Garcia A, Traves PG, Bonzon-Kulichenko E, Garcia-Marques F, Cusso L, N AG, Gonzalez-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzman G, Larrazabal J, Herrero-Galan E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Munoz-Canoves P, Ibanez B, Torres M, Ng LG, Priori SG, Bueno H, Vazquez J, Cordero MD, Bernal JA, Enriquez JA, Hidalgo A A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart Cell (2020) 183:94-109
    Link to the full text in Repisalud
    Garcia-Poyatos C, Cogliati S, Calvo E, Hernansanz-Agustin P, Lagarrigue S, Magni R, Botos M, Langa X, Amati F, Vazquez J, Mercader N, Enriquez JA Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish EMBO Rep (2020) 21:e50287
    Link to the full text in Repisalud
    Acin-Perez R, Hernansanz-Agustin P, Enriquez JA Analyzing electron transport chain supercomplexes Methods Cell Biol (2020) 155:181-197
    Lechuga-Vieco AV, Latorre-Pellicer A, Johnston IG, Prota G, Gileadi U, Justo-Méndez R, Acín-Pérez R, Martínez-de-Mena R, Fernández-Toro JM, Jimenez-Blasco D, Mora A, Nicolás-Ávila JA, Santiago DJ, Priori SG, Bolaños JP, Sabio G, Criado LM, Ruíz-Cabello J, Cerundolo V, Jones NS, Enríquez JA Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics Sci Adv (2020) 6:eaba5345
    Link to the full text in Repisalud
    Acin-Perez R, Iborra S, Marti-Mateos Y, Cook ECL, Conde-Garrosa R, Petcherski A, Munoz MDM, Martinez de Mena R, Krishnan KC, Jimenez C, Bolanos JP, Laakso M, Lusis AJ, Shirihai OS, Sancho D, Enriquez JA Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity Nat Metab (2020) 2:974-988
    Calvo E, Cogliati S, Hernansanz-Agustín P, Loureiro-López M, Guarás A, Casuso RA, García-Marqués F, Acín-Pérez R, Martí-Mateos Y, Silla-Castro J, Carro-Alvarellos M, Huertas JR, Vázquez J*, Enríquez JA* (JV and JAE are co-corresponding authors) Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Qpool Sci Adv (2020) 6:eaba7509
    Link to the full text in Repisalud
    Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hamalainen RH, Pellico J, Justo-Mendez R, Fernandez-Toro JM, Claveria C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruiz-Cabello J, Enriquez JA Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy Cell Metab (2019) 30:1120-30
    Link to the full text in Repisalud
    Enriquez JA Mind your mouse strain Nat Metab (2019) 1:5-7
    Acin-Perez R, Lechuga-Vieco AV, Del Mar Munoz M, Nieto-Arellano R, Torroja C, Sanchez-Cabo F, Jimenez C, Gonzalez-Guerra A, Carrascoso I, Beninca C, Quiros PM, Lopez-Otin C, Castellano JM, Ruiz-Cabello J, Jimenez-Borreguero LJ, Enriquez JA. Ablation of the stress protease OMA1 protects against heart failure in mice. Sci Transl Med (2018) 10:4935
    Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature (2016) 525:561-65
    Cogliati S*, Calvo E*, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vazquez J*, Enriquez JA* (SC and EC contributed equally; JV and JAE are co-corresponding authors) Mechanism of super-assembly of respiratory complexes III and IV. Nature (2016) 539:579-82
    Garaude J*, Acín-Pérez R, Martínez-Cano S, Enamorado M, Ugolini M, Nistal-Villán E, Hervás-Stubbs S, Pelegrín P, Sander LE, Enríquez JA*, Sancho D* (JG, JAE and DS are co-corresponding authors) Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defence Nat Immunol (2016) 17:1037-45
    Enriquez JA. Supramolecular Organization of Respiratory Complexes. Annu Rev Physiol (2016) 78:533-61
    Guaras A, Perales-Clemente E, Calvo E, Acin-Perez R, Loureiro-Lopez M, Pujol C, Martinez-Carrascoso I, Nunez E, Garcia-Marques F, Rodriguez-Hernandez MA, Cortes A, Diaz F, Perez-Martos A, Moraes CT, Fernandez-Silva P, Trifunovic A, Navas P, Vazquez J, Enriquez JA. The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency. Cell Rep (2016) 15:197-209
    Link to the full text in Repisalud
    Acín-Pérez R, Carrascoso I, Baixauli F, Roche-Molina M, Latorre-Pellicer A, Fernández-Silva P, Mittelbrunn M, Sánchez-Madrid F, Pérez-Martos A, Lowell CA, Manfredi G and Enríquez JA ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use. Cell Metab (2014) 19:1020-33
    Cogliati S, Frezza C, Soriano ME, Varanita T, Quintana-Cabrera R, Corrado M, Cipolat S, Costa V, Casarin A, Gomes LC, Perales-Clemente E, Salviati L, Fernandez-Silva P, Enriquez JA*, Scorrano L* (JAE and LS co-corresponding authors) Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency Cell (2013) 155:160-71
    Link to the full text in Repisalud
    Lapuente-Brun E, Moreno-Loshuertos R, Acin-Perez R, Latorre-Pellicer A, Colas C, Balsa E, Perales-Clemente E, Quiros PM, Calvo E, Rodriguez-Hernandez MA, Navas P, Cruz R, Carracedo A, Lopez-Otin C, Perez-Martos A, Fernandez-Silva P, Fernandez-Vizarra E, Enriquez JA Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain Science (2013) 340:1567-70

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