Publicaciones seleccionadas

Tiedt S, Buchan AM, Dichgans M, Lizasoain I, Moro MA, Lo EH. The neurovascular unit and systemic biology in stroke - implications for translation and treatment. NAT REV NEUROSCI (2022) 18:597-612
Endres M, Moro MA, Nolte CH, Dames C, Buckwalter MS, Meisel A. Immune Pathways in Etiology, Acute Phase, and Chronic Sequelae of Ischemic Stroke Circ Res (2022) 130:1167-1186
Li W, Mandeville ET, Durán-Laforet V, Fukuda N, Yu Z, Zheng Y, Held A, Park JH, Nakano T, Tanaka M, Shi J, Esposito E, Niu W, Xing C, Hayakawa K, Lizasoain I, van Leyen K, Ji X, Wainger BJ, Moro MA, Lo EH. Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke Nat Commun (2022) 13
Esposito E, Zhang F, Park JH, Mandeville ET, Li W, Cuartero MI, Lizasoaín I, Moro MA, Lo EH. Diurnal Differences in Immune Response in Brain, Blood and Spleen After Focal Cerebral Ischemia in Mice Stroke (2022) 53
Mandeville ET, Li W, Quinto-Alemany D, Zhang F, Esposito E, Nakano T, Mandeville JB, Lee J, Park JH, Arai K, Waeber C, Lizasoain I, Moro MÁ, Lo EH. Fingolimod Does Not Reduce Infarction After Focal Cerebral Ischemia in Mice During Active or Inactive Circadian Phases. Stroke (2022) 53
Hernández-Jiménez M, Martín-Vílchez S, Ochoa D, Mejía-Abril G, Román M, Camargo-Mamani P, Luquero-Bueno S, Jilma B, Moro MA, Fernández G, Piñeiro D, Ribó M, González VM, Lizasoain I, Abad-Santos F. First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers. Mol Ther Nucleic Acids (2022) 9:124-135
Peña-Martínez C, Durán-Laforet V, García-Culebras A, Cuartero MI, Moro MÁ, Lizasoain I. Neutrophil Extracellular Trap Targeting Protects Against Ischemic Damage After Fibrin-Rich Thrombotic Stroke Despite Non-Reperfusion. Front Immunol (2022) Feb 16 [Epub ahead of print]
Durán-Laforet V, Peña-Martínez C, García-Culebras A, Cuartero MI, Lo EH, Moro MÁ*, Lizasoain I*. Role of TLR4 in Neutrophil Dynamics and Functions: Contribution to Stroke Pathophysiology Front Immunol (2021) 12:757872
Adrover JM, del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity (2019) 50:390-402
Link to the full text in Repisalud
Cuartero MI, de la Parra J, Pérez-Ruiz A, Bravo-Ferrer I, Durán-Laforet V, García-Culebras A, García-Segura JM, Dhaliwal J, Frankland PW, Lizasoain I, Moro MA Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice J Clin Invest (2019) 129:1536-50
Garcia-Culebras A, Duran-Laforet V, Pena-Martinez C, Moraga A, Ballesteros I, Cuartero MI, de la Parra J, Palma-Tortosa S, Hidalgo A, Corbi AL, Moro MA, Lizasoain I Role of TLR4 (Toll-Like Receptor 4) in N1/N2 Neutrophil Programming After Stroke Stroke (2019) 50:2922-32
Peña-Martínez C, Durán-Laforet V, García-Culebras A, Ostos F, Hernández-Jiménez M, Bravo-Ferrer I, Pérez-Ruiz A, Ballenilla F, Díaz-Guzmán J, Pradillo JM, Lizasoain I, Moro MA Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance. Stroke (2019) 50:3228-3237
Bravo-Ferrer I, Cuartero MI, Medina V, Ahedo-Quero D, Peña-Martínez C, Pérez-Ruíz A, Fernández-Valle ME, Hernández-Sánchez C, Fernández-Salguero PM, Lizasoain I, Moro MA. Lack of the aryl hydrocarbon receptor accelerates aging in mice FASEB J (2019) 33:12644-54
Bravo-Ferrer I, Cuartero MI, Zarruk JG, Pradillo JM, Hurtado O, Romera VG, Díaz-Alonso J, García-Segura JM, Guzmán M, Lizasoain I, Galve-Roperh I, Moro MA Cannabinoid type-2 receptor drives neurogenesis and improves functional outcome after stroke Stroke (2017) 48:204-12
Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi M-D, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A Neutrophils scan for activated platelets to initiate inflammation Science (2014) 346:1234-8
Cuartero MI, Ballesteros I, Parra J, Harkin AL, Abautret-Daly A, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA Deleterious role of the aryl hydrocarbon receptor and its agonist l-kynurenin in acute ischemic brain damage Circulation (2014) 130:2040-51
García-Yébenes I, Sobrado M, Zarruk JG, Castellanos M, Pérez de la Ossa N, Dávalos A, Serena J, Lizasoain I, Moro MA A Mouse Model of Hemorrhagic Transformation by Delayed Tissue Plasminogen Activator Administration After in Situ Thromboembolic Stroke Stroke (2011) 42:196-203
Morales JR, Ballesteros I, Deniz JM, Hurtado O, Vivancos J, Nombela F, Lizasoain I, Castrillo A, Moro MA Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke Circulation (2008) 118:1450-9
Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke Circulation (2007) 115:1599-608