Selected publications

    Aroca-Crevillén A, Martín-Salamanca S, Torres LS, Crainiciuc G, Sicilia J, Peñaloza-Martínez E, Rosillo N, Molina-Moreno M, Adrover JM, Rubio-Ponce A, Vicanolo T, Liu X, Wichapong K, Núñez V, Balabanian K, Bachelerie F, Sancho D, Casanova-Acebes M, Ortiz-Pérez JT, Moro MÁ, Bueno H, Nicolaes GAF, Hidalgo A. A circadian checkpoint relocates neutrophils to minimize injury. J Exp Med (2026) 223:e20250240
    Cerezo-Wallis D, Rubio-Ponce A, Richter M, Pitino E, Kwok I, Marteletto G, Guanolema-Coba AC, Shih C, Huang RK, Moraga A, Bravo NB, Doré S, Callejas S, Aragonés DG, Jiménez-Carretero D, Martin D, Ovadia S, Vicanolo T, Crainiciuc G, Sicilia J, Deng T, Martin A, Zhang J, Cuartero MI, Giraldo DM, Garcia-Culebras A, Aroca-Crevillen A, Martín-Salamanca S, Torroja C, Ruiz M, Ruano I, Ng MSF, Hou J, Wang Y, Zhang M, Pu J, Herruzo A, van Oordt DC, Chang S, Downie AE, Chen F, Graham AL, Gause WC, Fiset PO, Spicer JD, Heyn H, Zuriaga MA, Bernal JA, Udalova IA, Moro MA, de Bock K, Dopazo A, Fuster JJ, Sánchez-Cabo F, Nieto JC, Calvo GF, Skokowa J, Soehnlein O, Quail DF, Walsh LA, Ng LG, Hidalgo A, Ballesteros I. Architecture of the neutrophil compartment Nature (2025) Dec 3 [Epub ahead of print]
    Vázquez-Reyes S, García-Culebras A, Di G, De Castro-Millán FJ, Díaz-Benito B, Nieto-Vaquero C, Ruiz-Sanchez A, Merino-Casamayor E, Parra-Pérez C, Moraga A, Core-Barrera C, Calleja P, Dopazo A, Callejas S, Rubio-Ponce A, Aroca-Crevillén A, Sánchez-Cabo F, Pascual El Bobakry S, Torroja C, Esposito E, Lo EH, Ballesteros I, Hidalgo A, Cuartero MI, Lizasoain I, Moro MÁ. Circadian Control of Neutrophils Drives Collateral Perfusion and Stroke Outcome. Circ Res (2025) Nov 26 [Epub ahead of print]
    Semerano A, Arenillas JF, McCullough LD, Moro MÁ. Targeting Innate Immune Memory for Stroke Prevention and Prognosis. Stroke (2025) 56:3095-3098
    Zeng Q, Oliva VM, Moro MÁ, Scheiermann C. Circadian Effects on Vascular Immunopathologies. Circ Res (2024) 134:791-809.
    Link to the full text in Repisalud
    Di G, Vazquez S, Díaz B, Peña-Martinez C, García-Culebras A, Cuartero MI, Moraga A, Pradillo JM, Esposito E, Lo EH, Moro MA*, Lizasoain I* Daytime DNase-I administration protects mice from ischemic stroke without inducing bleeding or tPA-induced hemorrhagic transformation, even with aspirin pretreatment. Stroke (2024) 56:527-532
    Link to the full text in Repisalud
    Torres-López C, Cuartero MI, García-Culebras A, de la Parra J, Fernández-Valle ME, Benito M, Vázquez-Reyes S, Jareño-Flores T, de Castro-Millán FJ, Hurtado O, Buckwalter MS, García-Segura JM, Lizasoain I, Moro MA. Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in Mice. Stroke (2023) 54:2652-2665
    Link to the full text in Repisalud
    Fraga E, Medina V, Cuartero MI, García-Culebras A, Bravo-Ferrer I, Hernández-Jiménez M, Garcia-Segura JM, Hurtado O, Pradillo JM, Lizasoain I, Moro MÁ. Defective hippocampal neurogenesis underlies cognitive impairment by carotid stenosis-induced cerebral hypoperfusion in mice. Front Cell Neurosci (2023) 17:1219847
    Link to the full text in Repisalud
    Hernández-Jiménez M, Abad-Santos F, Cotgreave I, Gallego J, Jilma B, Flores A, Jovin TG, Vivancos J, Hernández-Pérez M, Molina CA, Montaner J, Casariego J, Dalsgaard M, Liebeskind DS, Cobo E, Castellanos M, Portela PC, Masjuán J, Moniche F, Tembl JI, Terceño Izaga M, Arenillas JF, Callejas P, Olivot JM, Calviere L, Henon H, Mazighi M, Piñeiro D, Pugliese M, González VM, Moro MA, Garcia-Tornel A, Lizasoain I, Ribo M. Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial. JAMA Neurol (2023) 80:779-788
    Endres M, Moro MA, Nolte CH, Dames C, Buckwalter MS, Meisel A. Immune Pathways in Etiology, Acute Phase, and Chronic Sequelae of Ischemic Stroke Circ Res (2022) 130:1167-1186
    Li W, Mandeville ET, Durán-Laforet V, Fukuda N, Yu Z, Zheng Y, Held A, Park JH, Nakano T, Tanaka M, Shi J, Esposito E, Niu W, Xing C, Hayakawa K, Lizasoain I, van Leyen K, Ji X, Wainger BJ, Moro MA, Lo EH. Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke Nat Commun (2022) 13:7812
    Link to the full text in Repisalud
    Tiedt S, Buchan AM, Dichgans M, Lizasoain I, Moro MA, Lo EH. The neurovascular unit and systemic biology in stroke - implications for translation and treatment. Nat Rev Neurol (2022) 18:597-612
    Adrover JM, del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity (2019) 50:390-402
    Link to the full text in Repisalud
    Cuartero MI, de la Parra J, Pérez-Ruiz A, Bravo-Ferrer I, Durán-Laforet V, García-Culebras A, García-Segura JM, Dhaliwal J, Frankland PW, Lizasoain I, Moro MA Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice J Clin Invest (2019) 129:1536-50
    Peña-Martínez C, Durán-Laforet V, García-Culebras A, Ostos F, Hernández-Jiménez M, Bravo-Ferrer I, Pérez-Ruiz A, Ballenilla F, Díaz-Guzmán J, Pradillo JM, Lizasoain I, Moro MA Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance. Stroke (2019) 50:3228-3237
    Bravo-Ferrer I, Cuartero MI, Zarruk JG, Pradillo JM, Hurtado O, Romera VG, Díaz-Alonso J, García-Segura JM, Guzmán M, Lizasoain I, Galve-Roperh I, Moro MA Cannabinoid type-2 receptor drives neurogenesis and improves functional outcome after stroke Stroke (2017) 48:204-12
    Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi M-D, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A Neutrophils scan for activated platelets to initiate inflammation Science (2014) 346:1234-8
    Cuartero MI, Ballesteros I, Parra J, Harkin AL, Abautret-Daly A, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke Circulation (2014) 130:2040-51
    Cuartero MI, Ballesteros I, Moraga A, Nombela F, Vivancos J, Hamilton JA, Corbí ÁL, Lizasoain I, Moro MA N2 neutrophils, novel players in brain inflammation after stroke: modulation by the PPARγ agonist rosiglitazone Stroke (2013) 44:3498-508
    Morales JR, Ballesteros I, Deniz JM, Hurtado O, Vivancos J, Nombela F, Lizasoain I, Castrillo A, Moro MA Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke Circulation (2008) 118:1450-9

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