Publicaciones seleccionadas

Serrano AL, Munoz-Canoves P. Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications. Semin Cell Dev Biol (2017) 64:181-90
Garcia-Prat L, Munoz-Canoves P. Aging, metabolism and stem cells: Spotlight on muscle stem cells. Mol Cell Endocrinol (2017) 445:109-17
García-Prat L, Martínez-Vicente M, Perdiguero E, Ortet L, Rodríguez-Ubreva J, Rebollo E, Ruiz-Bonilla V, Gutarra S, Ballestar E, Serrano AL, Sandri M, Muñoz-Cánoves P Autophagy maintains stemness by preventing senescence Nature (2016) 529:37-42
Gómez-Del Arco P, Perdiguero E, Yunes-Leites PS, Acín-Pérez R, Zeini M, Garcia-Gomez A, Sreenivasan K, Jiménez-Alcázar M, Segalés J, López-Maderuelo D, Ornés B, Jiménez-Borreguero LJ, D'Amato G, Enshell-Seijffers D, Morgan B, Georgopoulos K, Islam AB, Braun T, de la Pompa JL, Kim J, Enriquez JA, Ballestar E, Muñoz-Cánoves P, Redondo JM The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis Cell Metab (2016) 23:881-92
Segalés J, Islam AB, Kumar R, Liu QC, Sousa-Victor P, Dilworth FJ, Ballestar E, Perdiguero E, Muñoz-Cánoves P Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation Skelet Muscle (2016) 6:9
Brack AS, Muñoz-Cánoves P The ins and outs of muscle stem cell aging Skelet Muscle (2016) 6:1
Sousa-Victor P, García-Prat L, Serrano AL, Perdiguero E, Muñoz-Cánoves P. Muscle stem cell aging: regulation and rejuvenation Trends Endocrinol Metab (2015) 26:287-96
Sousa-Victor P, Gutarra S, García-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardí M, Ballestar E, González S, Serrano AL, Perdiguero E, Muñoz-Cánoves P Geriatric muscle stem cells switch reversible quiescence into senescence Nature (2014) 506:316-21
Kharraz Y, Guerra J, Mann CJ, Serrano AL, Muñoz-Cánoves P. Macrophage plasticity and the role of inflammation in skeletal muscle repair Mediators Inflamm (2013) 2013:491497
Ardite E, Perdiguero E, Vidal B, Gutarra S, Serrano AL, Muñoz-Cánoves P PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy J Cell Biol (2012) 196:136-75
Vidal B, Ardite E, Suelves M, Ruiz-Bonilla V, Janué A, Flick MJ, Degen JL, Serrano AL, Muñoz-Cánoves P Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor Hum Mol Genet (2012) 21:1989-2004
Perdiguero E, Sousa-Victor P, Ruiz-Bonilla V, Jardí M, Caelles C, Serrano AL, Muñoz-Cánoves P p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair J Cell Biol (2011) 195:307-22
Serrano AL, Baeza-Raja B, Perdiguero E, Jardí M, Muñoz-Cánoves P Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy Cell Metab (2008) 7:33-44
Vidal B, Serrano AL, Tjwa M, Suelves M, Ardite E, De Mori R, Baeza-Raja B, Martínez de Lagrán M, Lafuste P, Ruiz-Bonilla V, Jardí M, Gherardi R, Christov C, Dierssen M, Carmeliet P, Degen JL, Dewerchin M, Muñoz-Cánoves P Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway Genes Dev (2008) 22:1747-52
Suelves M, Vidal B, Serrano AL, Tjwa M, Roma J, López-Alemany R, Luttun A, de Lagrán MM, Díaz-Ramos A, Jardí M, Roig M, Dierssen M, Dewerchin M, Carmeliet P, Muñoz-Cánoves P uPA deficiency exacerbates muscular dystrophy in MDX mice J Cell Biol (2007) 178:1039-51
Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation EMBO J (2007) 26:1245-56
Lluís F, Perdiguero E, Nebreda AR, Muñoz-Cánoves P Regulation of skeletal muscle gene expression by p38 MAP kinases Trends Cell Biol (2006) 16:36-44
Lluís F, Ballestar E, Suelves M, Esteller M, Muñoz-Cánoves P E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription EMBO J (2005) 24:974-84
Suelves M, Lluís F, Ruiz V, Nebreda AR, Muñoz-Cánoves P Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes EMBO J (2004) 23:365-75