Publicaciones seleccionadas

Cogliati S*, Calvo E*, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vazquez J*, Enriquez JA* (SC and EC contributed equally; JV and JAE are co-corresponding authors) Mechanism of super-assembly of respiratory complexes III and IV. Nature (2016) 539:579-82
del Olmo I, Lopez JA, Vazquez J, Raynaud C, Pineiro M, Jarillo JA Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing Nucleic Acids Res (2016) 44:5597-614
Blas-Rus N, Bustos-Moran E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, Jorge I, Vazquez J, Alarcon B, Malumbres M, Martin-Cofreces NB, Sanchez-Madrid F. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun (2016) 7:11389
Gonzalez-Teran B, Lopez JA, Rodriguez E, Leiva L, Martinez-Martinez S, Bernal JA, Jimenez-Borreguero LJ, Redondo JM, Vazquez J, Sabio G. p38gamma and delta promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. Nat Commun (2016) 7:10477
García-Marqués F, Trevisan-Herraz M, Martínez-Martínez S, Camafeita E, Jorge I, Lopéz JA, Méndez-Barbero N, Méndez-Ferrer S, Del Pozo MÁ, Ibáñez B, Andrés V, Sánchez-Madrid F, Redondo JM, Bonzon-Kulichenko E, Vázquez J. A novel systems-biology algorithm for the analysis of coordinated protein responses using quantitative proteomics Mol Cell Proteomics (2016) 15:1740-60
Nunez-Andrade N, Iborra S, Trullo A, Moreno-Gonzalo O, Calvo E, Catalan E, Menasche G, Sancho D, Vazquez J, Yao TP, Martin-Cofreces NB*, Sanchez-Madrid F*. (NBMC and FSM contributed equally) HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes. J Cell Sci (2016) 129:1305-11
Guaras A, Perales-Clemente E, Calvo E, Acin-Perez R, Loureiro-Lopez M, Pujol C, Martinez-Carrascoso I, Nunez E, Garcia-Marques F, Rodriguez-Hernandez MA, Cortes A, Diaz F, Perez-Martos A, Moraes CT, Fernandez-Silva P, Trifunovic A, Navas P, Vazquez J, Enriquez JA. The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency. Cell Rep (2016) 15:197-209
Navarro-Lérida I, Pellinen T, Sánchez SA, Guadamillas MC, Wang Y, Mirtti T, Calvo, Del Pozo MA. Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion Dev Cell (2015) 32:318-334
Strippoli R, Loureiro J, Moreno V, Benedicto I, Perez Lozano ML, Barreiro O, Pellinen T, Minguet S, Foronda M, Osteso MT, Calvo E, Vazquez J, Lopez Cabrera M, Del Pozo MA Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis EMBO Mol Med (2015) 7:102-23
Quiros PM, Espanol Y, Acin-Perez R, Rodriguez F, Barcena C, Watanabe K, Calvo E, Loureiro M, Fernandez-Garcia MS, Fueyo A, Vazquez J, Enriquez JA, Lopez-Otin C ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity Cell Rep (2014) 8:542-56
Lapuente-Brun E, Moreno-Loshuertos R, Acín-Pérez R, Latorre-Pellicer A, Colás C, Balsa E, Perales-Clemente E, Quirós PM, Calvo E, Rodríguez-Hernández MA, Navas P, Cruz R, Carracedo A, López-Otín C, Pérez-Martos A, Fernández-Silva P, Fernández-Vizarra E and Enríquez JA Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain Science (2013) 340:1567-70
Alvarez-Llamas G, Martin-Rojas T, de la Cuesta F, Calvo E, Gil-Dones F, Darde VM, Lopez-Almodovar LF, Padial LR, Lopez JA, Vivanco F, Barderas MG. Modification of the secretion pattern of proteases, inflammatory mediators and extracellular matrix proteins by human aortic valve is key in severe aortic stenosis. Mol Cell Proteomics (2013) 12:2426-39
Isern J, Martín-Antonio B, Ghazanfari R, Martín AM, López JA, Del Toro R, Sánchez-Aguilera A, Arranz L, Martín-Pérez D, Suárez-Lledó M, Marín P, Van Pel M, Fibbe WE, Vázquez J, Scheding S, Urbano-Ispizúa A, Méndez-Ferrer S. Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion. Cell Rep (2013) 3:1714-24
Balsa E, Marco R, Perales-Clemente E, Szklarczyk R, Calvo E, Landázuri MO, Enríquez JA. NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain Cell Metab (2012) 16:378-86
Goetz JG*, Minguet S*, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA (JGG and SM contributed equally) Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis Cell (2011) 146:148-63
Martinez-Pinna R, Ramos-Mozo P, Madrigal-Matute J, Blanco-Colio LM, Lopez JA, Calvo E, Camafeita E, Lindholt JS, Meilhac O, Delbosc S, Michel JB, Vega de Ceniga M, Egido J, Martin-Ventura JL. Identification of Peroxiredoxin-1 as a Novel Biomarker of Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol (2011) 4:935-43
Ramos-Mozo P, Madrigal-Matute J, Martinez-Pinna R, Blanco-Colio LM, Lopez JA, Camafeita E, Meilhac O, Michel JB, Aparicio C, de Ceniga MV, Egido J, Martín-Ventura JL. Proteomic Analysis of Polymorphonuclear Neutrophils Identifies Catalase as a Novel Biomarker of Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol (2011) 31:3011-9
Tuñon J, Martín-Ventura JL, Blanco-Colio LM, Lorenzo O, Lopez JA, Egido J. Proteomic strategies in the search of new biomarkers in atherothrombosis J Am Coll Cardiol (2010) 55:5009-16
Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nat Chem Biol (2007) 3:117-25
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet (2005) 37:391-400