Publicaciones seleccionadas

Nieto-Marín P, Tinaquero D, Utrilla RG, Cebrián J, González-Guerra A, Crespo-García T, Cámara-Checa A, Rubio-Alarcón M, Dago M, Alfayate S, Filgueiras D, Peinado R, López-Sendón JL, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpón E Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome Cardiovasc Res (2021) :cvab045
Gonzalez-Guerra A, Roche-Molina M, García-Quintáns N, Sánchez-Ramos C, Martín-Pérez D, Lytvyn M, de Nicolás-Hernández J, Rivera-Torres J, Arroyo DF, Sanz-Rosa D, Bernal JA Sustained Elevated Blood Pressure Accelerates Atherosclerosis Development in a Preclinical Model of Disease Int J Mol Sci (2021) 22:8448
Nicolas-Avila JA, Lechuga-Vieco AV, Esteban-Martinez L, Sanchez-Diaz M, Diaz-Garcia E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martinez-de-Mena R, Castejon-Vega B, Pun-Garcia A, Traves PG, Bonzon-Kulichenko E, Garcia-Marques F, Cusso L, N AG, Gonzalez-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzman G, Larrazabal J, Herrero-Galan E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Munoz-Canoves P, Ibanez B, Torres M, Ng LG, Priori SG, Bueno H, Vazquez J, Cordero MD, Bernal JA, Enriquez JA, Hidalgo A A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart Cell (2020) 183:94-109
Link to the full text in Repisalud
Roche-Molina M, Hardwick B, Sanchez-Ramos C, Sanz-Rosa D, Gewert D, Cruz FM, Gonzalez-Guerra A, Andres V, Palma JA, Ibanez B, McKenzie G, Bernal JA The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Kruppel-like factor 2 activation to reduce atherogenesis Sci Rep (2020) 10:11636
Link to the full text in Repisalud
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. p38gamma is essential for cell cycle progression and liver tumorigenesis Nature (2019) 568:557-60
Link to the full text in Repisalud
Cruz FM, Sanz-Rosa D, Roche-Molina M, Garcia-Prieto J, Garcia-Ruiz JM, Pizarro G, Jimenez-Borreguero LJ, Torres M, Bernad A, Ruiz-Cabello J, Fuster V, Ibanez B and Bernal JA. Exercise Triggers ARVC Phenotype in Mice Expressing a Disease-Causing Mutated Version of Human Plakophilin-2 J Am Coll Cardiol (2015) 65:1438-50
Roche-Molina M, Sanz-Rosa D, Cruz FM, Garcia-Prieto J, Lopez S, Abia R, Muriana FJ, Fuster V, Ibanez B, Bernal JA Induction of Sustained Hypercholesterolemia by Single Adeno-Associated Virus-Mediated Gene Transfer of Mutant hPCSK9 Arterioscler Thromb Vasc Biol (2015) 35:50-9
Lonardo E, Hermann PC, Muller MT, Huber S, Balic A, Miranda-Lorenzo I, Zagorac S, Alcala S, Rodriguez-Arabaolaza I, Ramirez JC, Torres-Ruiz R, Garcia E, Hidalgo M, Cebrian DA, Heuchel R, Lohr M, Berger F, Bartenstein P, Aicher A, Heeschen C. Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy Cell Stem Cell (2011) 9:433-46
Torres R, García A, Payá M, Ramirez JC. Non-Integrative Lentivirus Drives High-Frequency cre-Mediated Cassette Exchange in Human Cells. PLoS One (2011) 6:e19794.
Alonso-Ferrero ME, Valeri A, Yañez R, Navarro S, Garin MI, Ramirez JC, Bueren JA, Segovia JC. Immunoresponse against the transgene limits hematopoietic engraftment of mice transplanted in utero with virally transduced fetal liver. Gene Ther (2011) 18:469-78
Palao G, Santiago B, Galindo MA, Rullas JN, Alcamí J, Ramirez JC, Pablos JL. Fas activation of a proinflammatory program in rheumatoid synoviocytes and its regulation by FLIP and caspase 8 signaling. Arthritis Rheum (2006) 54:1473-81
Santiago B, Baleux F, Palao G, Gutiérrez-Cañas I, Ramírez JC, Arenzana-Seisdedos F, Pablos JL. CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans. ARTHRITIS RES THER (2006) 8:R43
Paya M, Segovia JC, Santiago B, Galindo M, del Rio P, Pablos JL, Ramírez JC. Optimising stable retroviral transduction of primary human synovial fibroblasts. J VIROL METHODS (2006) 137:95-102
Galindo M, Santiago B, Palao G, Gutierrez-Cañas I, Ramirez JC, Pablos JL. Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II. PEPTIDES (2005) 26:1647-53
Palao G, Santiago B, Galindo M, Payá M, Ramirez JC, Pablos JL. Down-regulation of FLIP sensitizes rheumatoid synovial fibroblasts to Fas-mediated apoptosis. Arthritis Rheum (2004) 50:2803-10
Didierlaurent A, Ramirez JC, Gherardi M, Zimmerli SC, Graf M, Orbea HA, Pantaleo G, Wagner R, Esteban M, Kraehenbuhl JP, Sirard JC. Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses. Vaccine (2004) 22:3395-403