AWHS, Aragon Workers Health Study
The Aragon Workers Health Study (AWHS) is being conducted in collaboration with the Instituto Aragonés de Ciencias de la Salud (IACS) and the General Motors factory in Zaragoza. The study examines the development of cardiovascular disease and its risk factors by monitoring factory workers at their annual medical checkups. AWHS is an open cohort study including more than 5000 workers. During 2010, study participants underwent a standardized clinical exam, laboratory assays, and collection of biological samples including serum, plasma, whole blood, urine and DNA.
A medical imaging facility has been established to allow further exploration of the presence of subclinical atherosclerosis in these participants. Over the next three years, participants will be examined for TC calcium score, 3D ultrasound of carotid arteries and abdominal aorta, and ankle-brachial index. All laboratory procedures have been reviewed and improved to meet the ISO 9001:2008 standard, verified by an external audit.
The study is financed by the Departamento de Salud y Consumo of the Aragon regional government and the CNIC. In addition, external funding has been raised for the following sub-studies on the cohort, which are being conducted by CNIC-based researchers: