Publicaciones seleccionadas

Paredes A, Justo-Méndez R, Jiménez-Blasco D, Núñez V, Calero I, Villalba-Orero M, Alegre-Martí A, Fischer T, Gradillas A, Sant'Anna VAR, Were F, Huang Z, Hernansanz-Agustín P, Contreras C, Martínez F, Camafeita E, Vázquez J, Ruiz-Cabello J, Area-Gómez E, Sánchez-Cabo F, Treuter E, Bolaños JP, Estébanez-Perpiñá E, Rupérez FJ, Barbas C, Enríquez JA, Ricote M. gamma-Linolenic acid in maternal milk drives cardiac metabolic maturation. Nature (2023) 618:365-373
Link to the full text in Repisalud
Menéndez-Gutiérrez MP, Porcuna J, Nayak RC, Paredes A, Niu H, Núñez V, Paranjpe A, Gómez MJ, Bhattacharjee A, Schnell DJ, Sánchez-Cabo F, Welch JS, Salomonis N, Cancelas JA, Ricote M. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood (2023) 141:592-608
Link to the full text in Repisalud
Di Martino O, Ferris MA, Hadwiger G, Sarkar S, Vu A, Menéndez-Gutiérrez MP, Ricote M, Welch JS. RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells. Haematologica. Haematologica (2022) 107:417-426
Link to the full text in Repisalud
Blanco-Domínguez R, Sánchez-Díaz R, de la Fuente H, Jiménez-Borreguero LJ, Matesanz-Marín A, Relaño M, Jiménez-Alejandre R, Linillos-Pradillo B, Tsilingiri K, Martín-Mariscal ML, Alonso-Herranz L, Moreno G, Martín-Asenjo R, García-Guimaraes MM, Bruno KA, Dauden E, González-Álvaro I, Villar-Guimerans LM, Martínez-León A, Salvador-Garicano AM, Michelhaugh SA, Ibrahim NE, Januzzi JL, Kottwitz J, Iliceto S, Plebani M, Basso C, Baritussio A, Seguso M, Marcolongo R, Ricote M, Fairweather D, Bueno H, Fernández-Friera L, Alfonso F, Caforio ALP, Pascual-Figal DA, Heidecker B, Lüscher TF, Das S, Fuster V, Ibáñez B, Sánchez-Madrid F, Martín P A Novel Circulating MicroRNA for the Detection of Acute Myocarditis N Engl J Med (2021) 384:2014-27
Link to the full text in Repisalud
Casanova-Acebes M, Menendez-Gutierrez MP, Porcuna J, Alvarez-Errico D, Lavin Y, Garcia A, Kobayashi S, Le Berichel J, Nunez V, Were F, Jimenez-Carretero D, Sanchez-Cabo F, Merad M, Ricote M RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression Nat Commun (2020) 11:1655
Link to the full text in Repisalud
Alonso-Herranz L, Sahun-Espanol A, Paredes A, Gonzalo P, Gkontra P, Nunez V, Clemente C, Cedenilla M, Villalba-Orero M, Inserte J, Garcia-Dorado D, Arroyo AG, Ricote M Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFbeta1 after myocardial infarction eLife (2020) 9:e57920
Link to the full text in Repisalud
Porcuna J, Menendez-Gutierrez MP, Ricote M Molecular control of tissue-resident macrophage identity by nuclear receptors Curr Opin Pharmacol (2020) 53:27-34
Link to the full text in Repisalud
Clemente C, Rius C, Alonso-Herranz L, Martin-Alonso M, Pollan A, Camafeita E, Martinez F, Mota RA, Nunez V, Rodriguez C, Seiki M, Martinez-Gonzalez J, Andres V, Ricote M, Arroyo AG. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis. Nat Commun (2018) 9:910
Link to the full text in Repisalud
Walter W, Alonso-Herranz L, Trappetti V, Crespo I, Ibberson M, Cedenilla M, Karaszewska A, Núñez V, Xenarios I, Arroyo AG, Sánchez-Cabo F*, Ricote M*. (FSC and MR are co-corresponding author) Deciphering the Dynamic Transcriptional and Post-transcriptional Networks of Macrophages in the Healthy Heart and after Myocardial Injury. Cell Rep (2018) 23:622-36
Link to the full text in Repisalud
A-Gonzalez N, Quintana JA, Garcia-Silva S, Mazariegos M, Gonzalez de la Aleja A, Nicolas-Avila JA, Walter W, Adrover JM, Crainiciuc G, Kuchroo VK, Rothlin CV, Peinado H, Castrillo A, Ricote M, Hidalgo A. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med (2017) 214:1281-96
Link to the full text in Repisalud
Menendez-Gutierrez MP, Roszer T, Fuentes L, Nunez V, Escolano A, Redondo JM, De Clerck N, Metzger D, Valledor AF, Ricote M Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling J Clin Invest (2015) 125:809-23
Link to the full text in Repisalud
Natrajan MS, de la Fuente AG, Crawford AH, Linehan E, Nunez V, Johnson KR, Wu T, Fitzgerald DC, Ricote M, Bielekova B, Franklin RJ. Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain (2015) 138:3581-97
Link to the full text in Repisalud
Walter W, Sanchez-Cabo F*, Ricote M* (*equal contribution) GOplot: an R package for visually combining expression data with functional analysis. Bioinformatics (2015) 31:2912-4
Link to the full text in Repisalud
Ma F, Liu SY, Razani B, Arora N, Li B, Kagechika H, Tontonoz P, Nunez V, Ricote M, Cheng G Retinoid X receptor alpha attenuates host antiviral response by suppressing type I interferon Nat Commun (2014) 5:5494
Link to the full text in Repisalud
Prieur X, Mok CY, Velagapudi VR, Núñez V, Fuentes L, Montaner D, Ishikawa K, Camacho A, Barbarroja N, O'Rahilly S, Sethi J, Dopazo J, Oresic M, Ricote M, Vidal-Puig A. (MR and AVP are co-corresponding authors) Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice. Diabetes (2011) 60:797-809
Link to the full text in Repisalud
Roszer T*, Menendez-Gutierrez MP*, Lefterova MI, Alameda D, Nunez V, Lazar MA, Fischer T, Ricote M (TR and MPMG contributed equally) Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor {gamma} or Retinoid X Receptor {alpha} Deficiency. J Immunol (2011) 186:621-31
Link to the full text in Repisalud
Núñez V*, Alameda D*, Rico D, Mota R, Gonzalo P, Cedenilla M, Fischer T, Boscá L, Glass CK, Arroyo AG, Ricote M (VN and DA contributed equally) Retinoid X receptor {alpha} controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A (2010) 107:10626-31
Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest (2007) 117:1658-69