Publicaciones seleccionadas

Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernandez-Calvo G, Khoyratty TE, van Grinsven E, Gonzalez-Hernandez S, Nicolas-Avila JA, Vicanolo T, Maccataio A, Benguria A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martin-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sanchez-Cabo F, Nistal-Villan E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A Co-option of Neutrophil Fates by Tissue Environments Cell (2020) Oct 23 [Epub ahead of print]
Dimitrov-Markov S, Perales-Paton J, Bockorny B, Dopazo A, Munoz M, Banos N, Bonilla V, Menendez C, Duran Y, Huang L, Perea S, Muthuswamy SK, Al-Shahrour F, Lopez-Casas PP, Hidalgo M Discovery of new targets to control metastasis in pancreatic cancer by single cell transcriptomics analysis of circulating tumor cells Mol Cancer Ther (2020) 19:1751-1760
MacGrogan D, Martínez-Poveda B, Desvignes JP, Fernandez-Friera L, Gomez MJ, Gil Vilariño E, Callejas Alejano S, García-Pavía P, Solis J, Lucena J, Salgado D, Collod-Béroud G, Faure E, Théron A, Torrents J, Avierinos JF, Montes L, Dopazo A, Fuster V, Ibáñez B, Sánchez-Cabo F, Zaffran S, de la Pompa JL Identification of a peripheral blood gene signature predicting aortic valve calcification Physiol Genomics (2020) Oct 12 [Epub ahead of print]
Tsilingiri K, de la Fuente H, Relano M, Sanchez-Diaz R, Rodriguez C, Crespo J, Sanchez-Cabo F, Dopazo A, Alonso-Lebrero JL, Vara A, Vazquez J, Casasnovas JM, Alfonso F, Ibanez B, Fuster V, Martinez-Gonzalez J, Martin P*, Sanchez-Madrid F*. (PM and FSM are co-corresponding authors) oxLDL Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease. Circulation (2019) 139:243-55
Link to the full text in Repisalud
Cortes-Canteli M, Kruyer A, Fernandez-Nueda I, Marcos-Diaz A, Ceron C, Richards AT, Jno-Charles OC, Rodriguez I, Callejas S, Norris EH, Sanchez-Gonzalez J, Ruiz-Cabello J, Ibanez B, Strickland S, Fuster V Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model J Am Coll Cardiol (2019) 74:1910-23
Link to the full text in Repisalud
Zagorac I, Fernandez-Gaitero S, Penning R, Post H, Bueno MJ, Mouron S, Manso L, Morente MM, Alonso S, Serra V, Munoz J, Gomez-Lopez G, Lopez-Acosta JF, Jimenez-Renard V, Gris-Oliver A, Al-Shahrour F, Pineiro-Yanez E, Montoya-Suarez JL, Apala JV, Moreno-Torres A, Colomer R, Dopazo A, Heck AJR, Altelaar M, Quintela-Fandino M. In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer. Nat Commun (2018) 9:3501
Link to the full text in Repisalud
Alvarez-Prado AF, Perez-Duran P, Perez-Garcia A, Benguria A, Torroja C, de Yebenes VG, Ramiro AR. A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets. J Exp Med (2018) 215:761-771
Link to the full text in Repisalud
De Andres C, Garcia MI, Goicoechea H, Martinez-Gines ML, Garcia-Dominguez JM, Martin ML, Romero-Delgado F, Benguria A, Sanjurjo M, Lopez-Fernandez LA. Genes differentially expressed by methylprednisolone in vivo in CD4 T lymphocytes from multiple sclerosis patients: potential biomarkers. Pharmacogenomics J (2018) 18:98-105
Talayero P, Alonso-Guirado L, Padilla G, Artaza H, Dopazo A, Sanchez-Cabo F, Rodriguez-Munoz S, Calvo-Pulido J, Mancebo E, de Lacoba MG, Paz-Artal E. 5-gene differential expression predicts stability of human intestinal allografts. Exp Mol Pathol (2017) 103:136-71
Municio C, Soler Palacios B, Estrada-Capetillo L, Benguria A, Dopazo A, Garcia-Lorenzo E, Fernandez-Arroyo S, Joven J, Miranda-Carus ME, Gonzalez-Alvaro I, Puig-Kroger A. Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis. Ann Rheum Dis (2016) 75:2157-65
Aguilera-Montilla N, Chamorro S, Nieto C, Sánchez-Cabo F, Dopazo A, Fernández-Salguero PM, Rodríguez-Fernández JL, Pello OM, Andrés V, Cuenda A, Alonso B, Domínguez-Soto A, Sánchez-Ramón S, Corbi AL. Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells. Blood (2013) 121:e108-17
Trigueros-Motos L, González-Granado JM, Cheung C, Fernández P, Sánchez-Cabo F, Dopazo A, Sinha S, Andrés V. Embryological-Origin-Dependent Differences in Hox Expression in Adult Aorta: Role in Regional Phenotypic Variability and Regulation of NF-κB Activity. Arterioscler Thromb Vasc Biol (2013) 33:1248-56
Link to the full text in Repisalud
Estrada JC, Torres Y, Benguría A, Dopazo A, Roche E, Carrera-Quintanar L, Pérez RA, Enríquez JA, Torres R, Ramírez JC, Samper E*, Bernad A* (ES and AB contributed equally) Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy. Cell Death Dis (2013) 4:e691
Link to the full text in Repisalud
Estrada JC, Albo C, Benguría A, Dopazo A, López-Romero P, Carrera-Quintanar L, Roche E, Clemente EP, Enríquez JA, Bernad A*, Samper E* (AB and ES contributed equally) Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis. Cell Death Differ (2012) 19:743-55
Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A*, González MA* (AB and MAG contributed equally) miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ (2011) 18:985-95
Sánchez-Ramos C, Tierrez A, Fabregat-Andrés O, Wild B, Sánchez-Cabo F, Arduini A, Dopazo A, Monsalve M. PGC-1[alpha] regulates translocated in liposarcoma activity: role in oxidative stress gene expression. Antiox Redox Sign (2011) 12:325-37
Martín Y, Dopazo A, Hernández-Chico C. Progress and challenges in developing a molecular diagnostic test for neurofibromatosis type 1. Expert Rev Mol Diagn (2011) 11:671-3
Callejas S*, Alvarez R*, Dopazo A (SC and RA contributed equally) Automatic Genomics: a user-friendly program for the automatic designing and plate loading of medium-throughput qPCR experiments. Biotechniques (2011) 50:46-50