Publicaciones seleccionadas

De Andres C, Garcia MI, Goicoechea H, Martinez-Gines ML, Garcia-Dominguez JM, Martin ML, Romero-Delgado F, Benguria A, Sanjurjo M, Lopez-Fernandez LA. Genes differentially expressed by methylprednisolone in vivo in CD4 T lymphocytes from multiple sclerosis patients: potential biomarkers. Pharmacogenomics J (2018) 18:98-105
Hill R, Madureira PA, Ferreira B, Baptista I, Machado S, Colaco L, Dos Santos M, Liu N, Dopazo A, Ugurel S, Adrienn A, Kiss-Toth E, Isbilen M, Gure AO, Link W. TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT. Nat Commun (2017) 8:14687
Talayero P, Alonso-Guirado L, Padilla G, Artaza H, Dopazo A, Sanchez-Cabo F, Rodriguez-Munoz S, Calvo-Pulido J, Mancebo E, de Lacoba MG, Paz-Artal E. 5-gene differential expression predicts stability of human intestinal allografts. Exp Mol Pathol (2017) 103:136-71
Municio C, Soler Palacios B, Estrada-Capetillo L, Benguria A, Dopazo A, Garcia-Lorenzo E, Fernandez-Arroyo S, Joven J, Miranda-Carus ME, Gonzalez-Alvaro I, Puig-Kroger A. Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis. Ann Rheum Dis (2016) 75:2157-65
Blanco FJ, Ojeda-Fernandez L, Aristorena M, Gallardo-Vara E, Benguria A, Dopazo A, Langa C, Botella LM, Bernabeu C Genome-wide transcriptional and functional analysis of endoglin isoforms in the human promonocytic cell line U937 J Cell Physiol (2015) 230:947-58
Hill R, Kalathur R, Callejas S, Colaco L, Brandao R, Serelde B, Cebria A, Blanco-Aparicio C, Pastor J, Futschik M, Dopazo A, Link W A novel Phosphatidylinositol 3-Kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes Breast Cancer Res (2014) 16:482
Aguilera-Montilla N, Chamorro S, Nieto C, Sánchez-Cabo F, Dopazo A, Fernández-Salguero PM, Rodríguez-Fernández JL, Pello OM, Andrés V, Cuenda A, Alonso B, Domínguez-Soto A, Sánchez-Ramón S, Corbi AL. Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells. Blood (2013) 121:e108-17
Trigueros-Motos L, González-Granado JM, Cheung C, Fernández P, Sánchez-Cabo F, Dopazo A, Sinha S, Andrés V. Embryological-Origin-Dependent Differences in Hox Expression in Adult Aorta: Role in Regional Phenotypic Variability and Regulation of NF-κB Activity. Arterioscler Thromb Vasc Biol (2013) 33:1248-56
López-Lera A, Sánchez Cabo F, Garrido S, Dopazo A, López-Trascasa M. Disease-modifying factors in hereditary angioedema: an RNA expression-based screening. Orphanet J Rare Dis (2013) 8:77
Estrada JC, Torres Y, Benguría A, Dopazo A, Roche E, Carrera-Quintanar L, Pérez RA, Enríquez JA, Torres R, Ramírez JC, Samper E*, Bernad A* (ES and AB contributed equally) Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy. Cell Death Dis (2013) 4:e691
Estrada JC, Albo C, Benguría A, Dopazo A, López-Romero P, Carrera-Quintanar L, Roche E, Clemente EP, Enríquez JA, Bernad A*, Samper E* (AB and ES contributed equally) Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis. Cell Death Differ (2012) 19:743-55
Lara-Pezzi E, Dopazo A, Manzanares M. Understanding cardiovascular disease: a journey through the genome (and what we found there). Dis Model Mech (2012) 5:434-43
Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A*, González MA* (AB and MAG contributed equally) miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ (2011) 18:985-95
Sánchez-Ramos C, Tierrez A, Fabregat-Andrés O, Wild B, Sánchez-Cabo F, Arduini A, Dopazo A, Monsalve M. PGC-1[alpha] regulates translocated in liposarcoma activity: role in oxidative stress gene expression. Antiox Redox Sign (2011) 12:325-37
Martín Y, Dopazo A, Hernández-Chico C. Progress and challenges in developing a molecular diagnostic test for neurofibromatosis type 1. Expert Rev Mol Diagn (2011) 11:671-3
Callejas S*, Alvarez R*, Dopazo A (SC and RA contributed equally) Automatic Genomics: a user-friendly program for the automatic designing and plate loading of medium-throughput qPCR experiments. Biotechniques (2011) 50:46-50
Sánchez-Cabo F, Rainer J, Dopazo A, Trajanoski Z, Hackl H. Insights into global mechanisms and disease by gene expression profiling. Methods Mol Biol (2011) 719:269-98
Vivas Y, Martinez-Garcia C, Izquierdo A, Garcia-Garcia F, Callejas S, Velasco I, Campbell M, Ros M, Dopazo A, Dopazo J, Vidal-Puig A, Medina-Gomez G. Early Peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass. BMC Med Genomics (2011) 4:86
Cubelos B, Sebastián-Serrano A, Beccari L, Calcagnotto ME, Cisneros E, Kim S, Dopazo A, Alvarez-Dolado M, Redondo JM, Bovolenta P, Walsh CA, Nieto M. Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron (2010) 66:523-35