Selected publications

    Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, Andrés E, An J, Segalés J, Ortet L, Lukesova V, Volpe G, Benguria A, Dopazo A, Benitah SA, Urano Y, Del Sol A, Esteban MA, Ohkawa Y, Serrano AL, Perdiguero E, Muñoz-Cánoves P. Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. Erratum for: Nature. 2023 Jan;613(7942):169-178. PMID: 36747036 Nature (2023) 613:169-178
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    Sánchez-Cabo F, Fuster V, Silla-Castro JC, González G, Lorenzo-Vivas E, Alvarez R, Callejas S, Benguría A, Gil E, Núñez E, Oliva B, Mendiguren JM, Cortes-Canteli M, Bueno H, Andrés V, Ordovás JM, Fernández-Friera L, Quesada AJ, Garcia JM, Rossello X, Vázquez J, Dopazo A, Fernández-Ortiz A, Ibáñez B, Fuster JJ, Lara-Pezzi E. Subclinical atherosclerosis and accelerated epigenetic age mediated by inflammation: a multi-omics study. Eur Heart J (2023) 4:2698-2709
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    Siguero-Álvarez M, Salguero-Jiménez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sánchez-Sáez F, Piñeiro-Sabarís R, Felipe-Medina N, Torroja C, José Gómez M, Sabater-Molina M, Escribá R, Richaud-Patin I, Iglesias-García O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibañez B, Monserrat L, María Pérez-Pomares J, Sánchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL. A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation (2023) 147:47-65
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    Aix E, Gallinat A, Yago-Díez C, Lucas J, Gómez MJ, Benguría A, Freitag P, Cortez-Toledo E, Fernández de Manuel L, García-Cuasimodo L, Sánchez-Iranzo H, Montoya MC, Dopazo A, Sánchez-Cabo F, Mercader N, López JE, Fleischmann BK, Hesse M, Flores I. Telomeres Fuse During Cardiomyocyte Maturation. Circulation (2023) 147:1634-1636
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    Villatoro A, Cuminetti V, Bernal A, Torroja C, Cossío I, Benguría A, Ferré M, Konieczny J, Vázquez E, Rubio A, Utnes P, You X, Fenton CG, Paulssen RH, Zhang J, Sánchez-Cabo F, Dopazo A, Vik A, Anderssen E, Hidalgo A, Arranz L. Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation. Author Correction: Nat Commun. 2023 Jan 3;14(1):12. PMID: 37391415 Nat Commun (2023) 14:12
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    Sánchez-Cerrillo I, Calzada-Fraile D, Triguero-Martínez A, Calvet-Mirabent M, Popova O, Delgado-Arévalo C, Valdivia-Mazeyra M, Ramírez-Huesca M, de Luis EV, Benguría A, Aceña-Gonzalo T, Moreno-Vellisca R, de Llano MA, de la Fuente H, Tsukalov I, Delgado-Wicke P, Fernández-Ruiz E, Roy-Vallejo E, Tejedor-Lázaro R, Ramiro A, Iborra S, Sánchez-Madrid F, Dopazo A, Álvaro IG, Castañeda S, Martin-Gayo E. MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to autoimmunity. EMBO J (2023) 42:e113714
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    Fernández-Chacón M, Mühleder S, Regano A, Garcia-Ortega L, Rocha SF, Torroja C, Sanchez-Muñoz MS, Lytvyn M, Casquero-Garcia V, De Andrés-Laguillo M, Muhl L, Orlich MM, Gaengel K, Camafeita E, Vázquez J, Benguría A, Iruela-Arispe ML, Dopazo A, Sánchez-Cabo F, Carter H, Benedito R. Incongruence between transcriptional and vascular pathophysiological cell states. Nature Cardiovascular Research (2023) 2:530-549
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    Gómez-Escolar C, Serrano-Navarro A, Benguria A, Dopazo A, Sánchez-Cabo F, Ramiro AR. Single cell clonal analysis identifies an AID-dependent pathway of plasma cell differentiation. EMBO Rep (2022) 23
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    Brandi P, Conejero L, Cueto FJ, Martínez-Cano S, Dunphy G, Gómez MJ, Relaño C, Saz-Leal P, Enamorado M, Quintas A, Dopazo A, Amores-Iniesta J, Del Fresno C, Nistal-Villán E, Ardavín C, Nieto A, Casanovas M, Subiza JL, Sancho D Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections Cell Rep (2022) 38
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    Delgado-Arévalo C, Calvet-Mirabent M, Triguero-Martinez A, Vázquez de Luis E, Benguría-Filippini A, Largo R, Calzada-Fraile D, Popova O, Sánchez-Cerrillo I, Tsukalov I, Moreno-Vellisca R, de la Fuente H, Herrero-Beaumont G, Ramiro AR, Sánchez-Madrid F, Castañeda S, Dopazo A, González-Álvaro I, Martin-Gayo E. NLRC4 -mediated activation of CD1c+ dendritic cells contributes to perpetuation of synovitis in rheumatoid arthritis. JCI Insight (2022) 7:e152886
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    López MG, Chiner-Oms Á, García de Viedma D, Ruiz-Rodriguez P, Bracho MA, Cancino-Muñoz I, D'Auria G, de Marco G, García-González N, Goig GA, Gómez-Navarro I, Jiménez-Serrano S, Martinez-Priego L, Ruiz-Hueso P, Ruiz-Roldán L, Torres-Puente M, Alberola J, Albert E, Aranzamendi Zaldumbide M, Bea-Escudero MP, Boga JA, Bordoy AE, Canut-Blasco A, Carvajal A, Cilla Eguiluz G, Cordón Rodríguez ML, Costa-Alcalde JJ, de Toro M, de Toro Peinado I, Del Pozo JL, Duchêne S, Fernández-Pinero J, Fuster Escrivá B, Gimeno Cardona C, González Galán V, Gonzalo Jiménez N, Hernáez Crespo S, Herranz M, Lepe JA, López-Causapé C, López-Hontangas JL, Martín V, Martró E, Milagro Beamonte A, Montes Ros M, Moreno-Muñoz R, Navarro D, Navarro-Marí JM, Not A, Oliver A, Palop-Borrás B, Parra Grande M, Pedrosa-Corral I, Pérez González MC, Pérez-Lago L, Pérez-Ruiz M, Piñeiro Vázquez L, Rabella N, Rezusta A, Robles Fonseca L, Rodríguez-Villodres Á, Sanbonmatsu-Gámez S, Sicilia J, Soriano A, Tirado Balaguer MD, Torres I, Tristancho A, Marimón JM; SeqCOVID-Spain consortium, Coscolla M, González-Candelas F, Comas I. The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant. Nat Genet (2021) 53:1405-1432
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    Pascual-Figal DA, Bayes-Genis A, Díez-Díez M, Hernández-Vicente Á, Vázquez-Andrés D, de la Barrera J, Vazquez E, Quintas A, Zuriaga MA, Asensio-López MC, Dopazo A, Sánchez-Cabo F, Fuster JJ Clonal Hematopoiesis and Risk of Progression of Heart Failure With Reduced Left Ventricular Ejection Fraction J Am Coll Cardiol (2021) 77:1747-1759
    Alcaraz-Serna A, Bustos-Morán E, Fernández-Delgado I, Calzada-Fraile D, Torralba D, Marina-Zárate E, Lorenzo-Vivas E, Vázquez E, de Alburquerque JB, Ruef N, Gómez MJ, Sánchez-Cabo F, Dopazo A, Stein JV, Ramiro A, Sánchez-Madrid F Immune synapse instructs epigenomic and transcriptomic functional reprogramming in dendritic cells Sci Adv (2021) 7:eabb9965
    Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernandez-Calvo G, Khoyratty TE, van Grinsven E, Gonzalez-Hernandez S, Nicolas-Avila JA, Vicanolo T, Maccataio A, Benguria A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martin-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sanchez-Cabo F, Nistal-Villan E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A Co-option of Neutrophil Fates by Tissue Environments Cell (2020) 183:1282-1297
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    Dimitrov-Markov S, Perales-Paton J, Bockorny B, Dopazo A, Munoz M, Banos N, Bonilla V, Menendez C, Duran Y, Huang L, Perea S, Muthuswamy SK, Al-Shahrour F, Lopez-Casas PP, Hidalgo M Discovery of new targets to control metastasis in pancreatic cancer by single cell transcriptomics analysis of circulating tumor cells Mol Cancer Ther (2020) 19:1751-1760
    MacGrogan D, Martínez-Poveda B, Desvignes JP, Fernandez-Friera L, Gomez MJ, Gil Vilariño E, Callejas Alejano S, García-Pavía P, Solis J, Lucena J, Salgado D, Collod-Béroud G, Faure E, Théron A, Torrents J, Avierinos JF, Montes L, Dopazo A, Fuster V, Ibáñez B, Sánchez-Cabo F, Zaffran S, de la Pompa JL Identification of a peripheral blood gene signature predicting aortic valve calcification Physiol Genomics (2020) 52:563-574
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    Tsilingiri K, de la Fuente H, Relano M, Sanchez-Diaz R, Rodriguez C, Crespo J, Sanchez-Cabo F, Dopazo A, Alonso-Lebrero JL, Vara A, Vazquez J, Casasnovas JM, Alfonso F, Ibanez B, Fuster V, Martinez-Gonzalez J, Martin P*, Sanchez-Madrid F*. (PM and FSM are co-corresponding authors) oxLDL Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease. Circulation (2019) 139:243-55
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    Cortes-Canteli M, Kruyer A, Fernandez-Nueda I, Marcos-Diaz A, Ceron C, Richards AT, Jno-Charles OC, Rodriguez I, Callejas S, Norris EH, Sanchez-Gonzalez J, Ruiz-Cabello J, Ibanez B, Strickland S, Fuster V Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model J Am Coll Cardiol (2019) 74:1910-23
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    Callejas S*, Alvarez R*, Benguria A, Dopazo A (SC and RA contributed equally) AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms. Biotechniques (2014) 56:28-35
    Lara-Pezzi E, Dopazo A, Manzanares M. Understanding cardiovascular disease: a journey through the genome (and what we found there). Dis Model Mech (2012) 5:434-43
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