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    E.g., 04/08/2025
    E.g., 04/08/2025
    Research
    29 Jun 2021
    JACC: Spanish scientists provide the first demonstration that triglycerides are a primary risk factor in atherosclerosis

    A study published in JACC shows that excess circulating triglyceride concentrations are associated with subclinical atherosclerosis and vascular inflammation in individuals with low-to-moderate cardiovascular risk according to standard scores
    Dra. Sabio
    About the CNIC
    17 Jun 2021
    Dr Guadalupe Sabio awarded the Banco Sabadell Foundation Prize for Biomedical Research

    The jury acknowledged this CNIC researcher's contribution to understanding why obesity causes cardiometabolic diseases.
    Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research
    7 Jun 2021
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart
    Association between the level of glycosylated hemoglobin and the extent of subclinical atherosclerosis
    Research
    31 May 2021
    JACC: A blood sugar biomarker identifies patients with atherosclerosis and a risk of cardiovascular events

    In an article published in JACC, CNIC scientists report a method for improved ranking of cardiovascular risk in individuals without diabetes
    David Sancho, Carlos del Fresno, Elena Hernández-García, Manuel José Gómez, Francisco Javier Cueto, Salvador Iborra y Paola Brandi.
    Research
    14 May 2021
    JITC: CNIC scientists discover a new strategy to improve cancer immunotherapy

    Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have designed a new strategy to potentiate immunotherapy, the treatment that has revolutionized cancer management
    Sara Martínez Martínez, María José Méndez Olivares, Álvaro Alfayate, , Andrea de la Fuente-Alonso, Miguel R. Campanero, Juan Miguel Redondo y Jesús Vázquez.
    Research
    11 May 2021
    Nature Communications: Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

    Scientists at the CNIC and CSIC have shown that elevated activity of proteins regulated by nitric oxide (NO) causes the aortic disease seen in Marfan Syndrome patients
    Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
    About the CNIC
    13 Apr 2021
    JACC: CNIC researchers explain how high blood pressure, the most important cause of disease worldwide, accelerates atherosclerosis

    The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy
    Mª Ángeles Zuriaga, Mirian Díez, Fátima Sánchez-Cabo, Ana Dopazo, José Javier Fuster, Ana Quintas y Jorge de la Barrera.
    Research
    5 Apr 2021
    JACC: CNIC scientists identify mutations acquired by blood cells that accelerate heart failure progression

    The study, carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia, establishes clonal hematopoiesis as a new cardiovascular risk factor and an important link between aging and cardiovascular disease
    Valentín Fuster
    About the CNIC
    25 Feb 2021
    The Association of Cardiovascular Imaging of the Spanish Society of Cardiology (SEC) awards its Gold Medal to Dr Valentín Fuster

    Dr Valentín Fuster, Director of the Spanish National Centre for Cardiovascular Research (CNIC) is to receive the Gold Medal of the Association of Cardiovascular Imaging of the Spanish Society of Cardiology (SEC) for his original and innovative scientific activity in cardiovascular imaging to reach new frontiers in cardiovascular health of the heart and brain.
    3D reconstructions of superior (left) and inferior (right) brain regions, showing regions with lower metabolism associated with the presence of atherosclerotic plaques in the carotid arteries. The color code indicates the magnitude of the observation (yellow, strong association; red, lower association). Gray indicates areas showing no association with carotid plaque presence
    Research
    15 Feb 2021
    JACC: Spanish scientists uncover early links between cardiovascular risk and brain metabolism

    Among the modifiable cardiovascular risk factors showing a close association with reduced brain metabolism, the research team found that the most important is hypertension