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The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed.

TROPOSplice proposes an evolution-inspired strategy to improve cardiac relaxation in patients with hypertrophic cardiomyopathy and heart failure with preserved ejection fraction.

A new analysis of the DapaTAVI trial, published in the European Journal of Heart Failure, confirms that dapagliflozin improves outcomes after TAVI regardless of cardiac function.

Left ventricular hypertrabeculation, an anatomical feature of the heart traditionally linked to higher risk, does not worsen outcomes in patients with dilated cardiomyopathy

The study reveals that the early heart is shaped by distinct but closely coordinated patterns of tissue deformation 

Hypertrophic cardiomyopathy is the most common inherited heart disease and the leading cause of sudden cardiac death in young people and athletes

Two CNIC teams have developed a pioneering technique to analyze proteins in individual cardiomyocytes and uncover new clues about cardiac regeneration

CARDIOSWITCH aims to uncover how the mechanical activity of heart muscle cells shapes cardiac biology and to develop new regenerative strategies for congenital heart disease