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Researchers at the CNIC, in collaboration with the University of Pavia and IRCCS Istituti Clinici Scientifici Maugeri, have found that activation of the enzyme calpain contributes to the development of a severe inherited arrhythmia.

A new study, published in the Journal of the American Heart Association, shows that individuals with elevated levels of both proteins have twice the risk of cardiovascular events.

The findings could help more precisely identify candidates for a preventive implantable defibrillator

The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed.

TROPOSplice proposes an evolution-inspired strategy to improve cardiac relaxation in patients with hypertrophic cardiomyopathy and heart failure with preserved ejection fraction.

The protein, OMA1, delays immune-system overactivation, liver fibrosis, and liver cancer during aging

The findings suggest that a risk-based personalized approach may be more efficient than applying intensive surveillance protocols uniformly to all patients. 

The study reveals that the early heart is shaped by distinct but closely coordinated patterns of tissue deformation