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    E.g., 06/07/2025
    E.g., 06/07/2025
    Cells use two mechanisms to detect force: one gradual and progressive mediated by newly identified large membrane depressions called dolines (left); the other abrupt, activated above a certain threshold, and mediated by minute membrane invaginations called caveolae (right).
    Research
    23 Dec 2022
    Nature Cell Biology: A CNIC study shows that cells possess 2 mechanisms to allow them to respond to different force ranges

    A study published in Nature Cell Biology confirms that caveolae are essential for the mechanical responses of tissues subject to large mechanical forces (such as muscle, heart, blood vessels, and fat), whereas larger membrane depressions (termed 'dolines') are important for the response to weak or medium-strength forces
    Cellular and Molecular Sciences: Describen un nuevo mecanismo que relaciona la inflamación y el remodelado cardiovascular patológico
    Research
    29 Sep 2022
    Cellular and Molecular Sciences: Describing a new mechanism that links inflammation and pathological cardiovascular remodelling
    Los adolescentes que duermen menos de 8 horas tienen más probabilidades de tener sobrepeso u obesidad
    Research
    29 Aug 2022
    Insufficient sleep in teenagers is associated with overweight and obesity

    Excess weight and metabolic syndrome are associated with cardiovascular disease, suggesting that health promotion programs in schools should teach good sleep habits
    Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
    Research
    29 Jun 2022
    eLife: Study reveals how Duchenne muscular dystrophy causes heart rhythm problems

    Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”
    Juan Domingo Gisbert
    About the CNIC
    24 Jun 2022
    Juan Domingo Gisbert: "Combining CNIC and BBRC data will allow us to answer questions of great relevance for the prevention of Alzheimer's in healthy subjects"

    Juan Domingo Gispert López, head of the Barcelonaβeta Brain Research Center and CNIC (Spanish National Centre for Cardiovascular Research) researcher
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    Dr. Cristóbal Belda se convirtió en el nuevo Director del Instituto de Salud Carlos III.
    Research
    11 May 2022
    Cristóbal Belda, Director del ISCIII: “PERTE represents an opportunity to help our country”
    About the CNIC
    26 Jan 2022
    Dr. Valentín Fuster, awarded for his social commitment as a disseminator and promoter of healty habits among the population
    Miguel Palomino Segura, Georgiana Crainiciuc, Jon Sicilia y Andrés Hidalgo
    Research
    5 Jan 2022
    Nature: CNIC scientists discover a cell behavior pattern that predicts cardiovascular disease

    Scientists at the CNIC have developed a simple model for studying the behavior of immune cells in live animals and have identified a harmful cell behavior pattern associated with cardiovascular disease
    Álvaro Macías, Jesús Vázquez, Pilar Gonzalo, Carla Espinós, Beatriz Dorado, Emilio Camafeita, Vicente Andrés, María J Andrés, Cristina González, Amanda Sánchez, Víctor Fanjul.
    Research
    26 Oct 2021
    CIRCULATION: It's never too late to treat progeria

    Scientists from the CNIC and the CIBERCV have generated the first experimental animal model that develops Hutchinson-Gilford Progeria Syndrome and allows its controlled reversal