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Los complejos I, III, y IV de la cadena de transporte electrónico mitocondrial se asocian formando grandes estructuras llamadas supercomplejos.  SCAF1 determina la asociación entre complejos de la cadena de transporte mitocondrial.
Research
18 Oct 2022

A study, published in Nature Metabolism, is the first to demonstrate the key role played by mitochondria in adapting metabolism to different energy demands in humans

About the CNIC
23 Aug 2022

The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people

Research
17 Mar 2022

The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulation

Research
30 Jul 2020

CNIC study shows that selection between mitochondrial genomes depends on how each type of mitochondria affects cell metabolism

Research
30 Jul 2020

The study, published in Nature, shows that sodium controls hypoxic signaling in the mitochondrial respiratory chain

Research
25 Jun 2020

The regulatory protein SCAF1 enables mitochondria to adapt to the available nutrient source of sugars, fats, or proteins


Rocío Sierra, José María Fernández-Toro, Cristina Clavería, Raquel Justo-Méndez, José Antonio Enríquez, Ana Victoria Lechuga-Vieco y Luis Miguel Criado.
Research
4 Oct 2019

CNIC researchers have defined the dynamics of  the transfer of mitochondrial DNA from mothers to their offspring

Daniel Torralba, Prof. Francisco Sánchez Madrid, Dra. Carolina Villaroya-Beltri, Irene Fernandez-Delgado, Dra. Noa Martín-Cófreces.
Research
10 Jul 2018

CNIC researchers demonstrate that exosomes transferred from T lymphocytes to dendritic cells contain mitochondrial DNA

Jesús Mª Vázquez Cobos, Enrique Calvo, Rebeca Acín Pérez, José Antonio Enríquez, Ana Victoria Lechuga-Vieco, Ignacio Flores, Carlos Torroja, Fátima Sánchez Cabo, Jesús Ruiz-Cabello y Andrés González Guerra.
Research
7 Jul 2016

The study, published in Nature, provides information with important implications for mitochondrial donation therapies, which produce children with three genetic parents

CNIC Scientists  David Sancho, Rebeca Acín-Pérez, Michel Enamorado Escalona, José A. Enríquez y Sarai Martínez-Cano
Research
28 Jun 2016

CNIC scientists reveal how changes in the metabolism of mitochondria allow the cells of the immune system to adapt to living or dead bacteria