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    E.g., 15/10/2025
    E.g., 15/10/2025
    Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research
    7 Jun 2021
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart
    From left to right: Marta Román, Fernando Domínguez, Laura Padrón-Barthe, Pablo Garcia-Pavia, Giovanna Giovinazzo, Enrique Lara-Pezzi, Demetrio J. Santiago, Javier Larrasa-Alonso
    Research
    5 Sep 2019
    Circulation: Possible treatment breakthrough for the rare disease arrhythmogenic right ventricular cardiomyopathy type 5

    Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Puerta de Hierro hospital in Majadahonda have found a possible treatment for this disease
    Research
    3 Dec 2015
    CNIC researchers discover link between a mitochondrial defect and heart disease

    A defect in mitochondria in the heart causes dilated cardiomyopathy, leading to heart disease and early death