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    E.g., 25/08/2026
    E.g., 25/08/2026
    Fernando de Frutos y el Dr. Pablo García Pavía.
    Research
    29 Aug 2022
    JACC: CNIC scientists describe key features of one of the most frequent forms of hereditary dilated cardiomyopathy

    The findings, published in the Journal of the American College of Cardiology (JACC), represent a first step towards the personalized treatment of patients with this disease
    Imagen de histología que muestra la comparación del tamaño del corazón de un ratón normal (izquierda) y un ratón deficiente para la proteína MKK6 (derecha).
    Research
    9 Aug 2022
    eLife: CNIC scientists uncover opposing roles of p38 proteins in cardiac hypertrophy

    A new study published in eLife shows that inhibition of p38γ/δ is a potential therapeutic strategy for the treatment of hypertrophic cardiomyopathy, but that this strategy has yet to be explored because of the lack of specific inhibitors for these p38 family members
    Dr. Pablo García-Pavía y Dr. Jesús Gonzalez Mirelis, codirectores del trabajo.
    Research
    22 Jul 2022
    EJHF: Spanish scientists combine genetic and imaging data to improve the treatment of dilated cardiomyopathy

    Genetic screening combined with the detection of fibrosis identifies patients at risk of malignant arrhythmias or developing heart failure with severe complications
    Grupo de la Dra. Priori
    Research
    21 Jul 2021
    A CNIC project receives funding from the ”la Caixa” Foundation to investigate a type of fatal tachycardia

    The research team led by project leader Dr Silvia Priori is confident that the discovery of new therapies will reduce the mortality linked to this disease and could also reduce arrhythmias in heart failure patients

    Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research
    7 Jun 2021
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart
    From left to right: Marta Román, Fernando Domínguez, Laura Padrón-Barthe, Pablo Garcia-Pavia, Giovanna Giovinazzo, Enrique Lara-Pezzi, Demetrio J. Santiago, Javier Larrasa-Alonso
    Research
    5 Sep 2019
    Circulation: Possible treatment breakthrough for the rare disease arrhythmogenic right ventricular cardiomyopathy type 5

    Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Puerta de Hierro hospital in Majadahonda have found a possible treatment for this disease
    Research
    3 Dec 2015
    CNIC researchers discover link between a mitochondrial defect and heart disease

    A defect in mitochondria in the heart causes dilated cardiomyopathy, leading to heart disease and early death