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Lam NT, Nguyen NUN, Elhelaly WM, Hsu CC, Menendez-Montes I, Xiao F, Ali SR, Vo N, Briard N, El-Feky L, Omari QM, Cardoso AC, Liu Y, Ahmed MS, Li S, Thet S, Xing C, Zangi L, Sadek HA. Induced Cytokinesis Generates Highly Proliferative Mononuclear Cardiomyocytes at the Expense of Contractility. Circulation (2025) 151:1009-1023
Mahmoud AI, Sadek HA. Leveraging Transcriptional Readouts as a Platform for Drug Repurposing in Cardiomyopathy. Circulation (2025) 151:1449-1450
Wang P, Ahmed MS, Nguyen NUN, Menendez-Montes I, Hsu CC, Farag AB, Thet S, Lam NT, Wansapura JP, Crossley E, Ma N, Zhao SR, Zhang T, Morimoto S, Singh R, Elhelaly W, Tassin TC, Cardoso AC, Williams NS, Pointer HL, Elliott DA, McNamara JW, Watt KI, Porrello ER, Sadayappan S, Sadek HA. An FDA-approved drug structurally and phenotypically corrects the K210del mutation in genetic cardiomyopathy models. J Clin Invest (2025) 135:e174081
Link to the full text in Repisalud
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Ali SR, Nguyen NUN, Elhelaly W, Hsu CC, Li S, Menendez-Montes I, Wang Z, Cui M, Elnwasany A, Xiao F, Sun J, Thet S, Lam NT, Cardoso A, Pereira AH, Wang J, Olson EN, Kinter MT, Szweda LI, Shelton J, Kimura W, Sadek HA. Paracrine IGFBP3 spatially coordinates IGF signaling to induce myocardial regeneration in mice. J Mol Cell Cardiol (2025) 207:93-106
Fuentes-Baile M, García-Morales P, Pérez-Valenciano E, Mata-Balaguer T, Menéndez-Gutiérrez MP, de Juan Romero C, Rodríguez-Lescure Á, Martín-Orozco E, Mallavia R, Barberá VM, Saceda M. Insights into histone deacetylase inhibitors-induced cell death in cancer cell lines. Biomed Pharmacother (2025) 191:118541
Link to the full text in Repisalud
Link to the full text in Repisalud
Xiao F, Nguyen NUN, Wang P, Li S, Hsu CC, Thet S, Kimura W, Luo X, Lam NT, Menendez-Montes I, Elhelaly W, Cardoso AC, Pereira AHM, Singh R, Sadayappan S, Kanchwala M, Xing C, Ladha FA, Hinson JT, Hajjar RJ, Hill JA, Sadek HA. Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis. Circulation (2024) 150:791-805
Link to the full text in Repisalud
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Ali SR, Sadek HA. Cardiomyocyte DNA Damage Predicts Functional Recovery in Heart Failure Patients. JACC Heart Fail (2024) 12:662-664
Ali SR, Nguyen NUN, Menendez-Montes I, Hsu CC, Elhelaly W, Lam NT, Li S, Elnwasany A, Nakada Y, Thet S, Foo RSY, Sadek HA. Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage. J Cardiovasc Aging (2024) 4:11
Link to the full text in Repisalud
Link to the full text in Repisalud
Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. Transient regenerative potential of the neonatal mouse heart. Science (2011) 331:1078-80






