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Pricolo MR, López-Unzu MA, Vicente N, Morales-López C, Huerta-López C, Pérez-Franco W, Dumitru AC, Peña-Peña J, Espinosa FM, Sanchez MI, Garcia R, Silva-Rojas R, Torres M, Herrero-Galán E, Alegre-Cebollada J. Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation. J Biol Chem (2026) 302:113167
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Martinez-Martin, Inés; Silva-Rojas, Roberto; Alegre-Cebollada, Jorge Mending the Achilles heels of titin in cardiac and musculoskeletal disease. Biophys Rev (2026) 18:169-190
Link to the full text in Repisalud
Link to the full text in Repisalud
Sen-Martín L, Fernández-Trasancos Á, López-Unzu MÁ, Bak A, Zafra-Castellano M, Srikantharajah R, Pathak D, Klotz A, Kuehn MN, Ferrarini A, Labrador-Cantarero V, Sánchez-Ortiz D, Pricolo MR, Vicente N, Velázquez-Carreras D, Sánchez-García L, Sicilia J, Nicolás-Ávila JÁ, Sánchez-Díaz M, Schlossarek S, Cussó L, Desco M, Villalba-Orero M, Guzmán-Martínez G, Calvo E, Barriales-Villa R, Vázquez J, Sánchez-Cabo F, Hidalgo A, de Tombe PP, Carrier L, Spudich JA, Ruppel KM, Weinberger F, Cazorla O, Hessel AL, Alegre-Cebollada J. Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy. Nature Cardiovascular Research (2026) Jul 7 [Epub ahead of print]
bioRxiv [Preprint]
bioRxiv [Preprint]
Vicanolo T, Özcan A, Li JL, Huerta-López C, Ballesteros I, Rubio-Ponce A, Dumitru AC, Nicolás-Ávila JÁ, Molina-Moreno M, Reyes-Gutierrez P, Johnston AD, Martone C, Greto E, Quílez-Alvarez A, Calvo E, Bonzon-Kulichenko E, Álvarez-Velez R, Chooi MY, Kwok I, González-Bermúdez B, Malleret B, Espinosa FM, Zhang M, Wang YL, Sun D, Zhen Chong S, El-Armouche A, Kim KK, Udalova IA, Greco V, Garcia R, Vázquez J, Dopazo A, Plaza GR, Alegre-Cebollada J, Uderhardt S, Ng LG, Hidalgo A. Matrix-producing neutrophils populate and shield the skin. Nature (2025) 641:740-748
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Link to the full text in Repisalud
Pozo-Vilumbrales B, Martín-Chaves L, López-Unzu MA, Soto-Navarrete MT, Pavón-Morón FJ, Rodríguez-Capitán J, Fernández B. Unraveling the molecular complexity of bicuspid aortopathy: Lessons from comparative proteomics. BBA-MOL BASIS DIS (2025) 1871:167679
Soto-Navarrete MT, Pozo-Vilumbrales B, López-Unzu MÁ, Martín-Chaves L, Durán AC, Fernández B. Endocardial-to-mesenchymal transition underlies cardiac outflow tract septation and bicuspid aortic valve formation in the Syrian hamster model. Sci Rep (2025) 15:8583-8597
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Silva-Rojas R, Vicente N, Gavilán-Herrera M, Labrador-Cantarero V, Sicilia J, Giménez-Sáez O, Dumitru AC, Sánchez MI, Gato-Vilaseca M, Velázquez-Carreras D, López JA, Vázquez J, Herrero-Galán E, López-Unzu MA, Pricolo MR, Alegre-Cebollada J. Mechanically knocking out titin reveals protein tension loss as a trigger of muscle disease. Nat Biomed Eng (2025) 9:1758-1774
Link to the full text in Repisalud
Link to the full text in Repisalud
David SO, Lucía DB, Lucía HM, Marta FR, Juvenal RL, Diana SM, Carlos LL, Juan Carlos LG, Federico GL. Case Report: Two-month-old infant with PHACE syndrome: facial hemangioma and severe complex coarctation of the aorta. Front Cardiovasc Med (2025) 12:1539168
Link to the full text in Repisalud
Link to the full text in Repisalud
Douvdevany G, Erlich I, Haimovich-Caspi L, Mashiah T, Prondzynski M, Pricolo MR, Alegre-Cebollada J, Linke WA, Carrier L, Kehat I. Imaging of Existing and Newly Translated Proteins Elucidates Mechanisms of Sarcomere Turnover. Circ Res (2024) 135:474-487
López-Unzu MA, Teresa Soto-Navarrete M, Sans-Coma V, Fernández B, Carmen Durán A. The myoarchitecture of the vertebrate cardiac ventricles: evolution and classification. J EXP BIOL (2024) 227:jeb247441
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