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E.g., 23/02/2026
E.g., 23/02/2026
Ana Simón Chica y David Filgueiras Rama
Research
10 Feb 2026

The study, published in Circulation Research, identifies cardiac fibroblasts and resident macrophages as essential contributors to the characteristic electrical activity that maintains this arrhythmia

Equipo de investigadores del CNIC liderados por la Dr. Mª Ángeles Moro. De izquierda a derecha, primera fila: Ignacio Lizasoain, Gaohong Di, Maria Angeles Moro, Alicia García-Culebras, Maria Isabel Cuartero, Francisco J. de Castro-Millan, Abndrea Rubio-Ponce, Carlos Parra-Pérez, Christina Reyburn-Valés, Carlona Peña-Martinez, Marta Marty. Segunda fila: Francisco Cantero-Molina, Eneko Merino-Casamayor, Virginia García-Sánchez, Laiura Martínez-. Cortés, Hana Matuskova, Emily McMahon
Research
20 Jan 2026

The study, published in Circulation Research, reveals that neutrophils—key immune cells—change their behavior in line with circadian rhythms, affecting cerebral perfusion and collateral circulation

Sarai Martínez Cano, Marcos Femenía Muiña, Elena Hernández, Vanessa Núñez, Manuel Rodrigo Tapias, Miguel Galán Burgos, Iñaki Robles,  Alberto Benguria, David Sancho y Almudena Ramiro
Research
2 Jun 2025

A team from the CNIC has discovered the key role of conventional type 1 dendritic cells (cDC1) in atherosclerosis and has developed an experimental therapy with immunosuppressive nanoparticles that slows the progression of the disease in animal models.

Juan Pablo Ochoa, Pablo García-Pavía, Laura Lalaguna, Marina López-Olañeta, María Arévalo-Núñez de Arenas y Enrique Lara-Pezzi.
Research
9 Apr 2025

A CNIC team has developed an innovative gene therapy strategy for arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly inherited condition that particularly affects young men

Enrique Lara-Pezzi, Laura Lalaguna, Benedetta Coppe, Nadia Mercader y María  Galardi-Castilla.
Research
2 Apr 2025

Scientists at the CNIC and the University of Bern have found that heart surgery in male mice early in life creates a "memory" passed down to the next generation. Published in Circulation, the study suggests that a parental history of heart surgery should be considered when evaluating cardiovascular health in descendants.

Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
Research
19 Sep 2024

A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk

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Research
9 Sep 2024

The new study, published in the journal Circulation, opens a new avenue of research into treatments for the atherosclerosis associated with progeria

María Jesús Andrés, Carla Espinós (detrás), Rosa M Nevado (delante, al lado de MJA), Miguel de la Fuente, Rosa Carmona, Ana Barettino, Vicente Andrés, Pilar Gonzalo e Ignacio Benedicto.
Research
19 Apr 2024

The elimination of progerin from vascular smooth muscle cells, but not from endothelial cells, prevents the atherosclerosis associated with Hutchinson-Gilford progeria syndrome (HGPS)

María Linarejos Vera, Gema Mondéjar, Amaia Talavera, Patricia Sánchez, Álvaro Macías, Juan Manuel Ruiz, Francisco M. Cruz, Fernando Martínez de Benito, Juan Antonio Bernal y José Jalife
Research
11 Apr 2024

CNIC researchers, led by Dr. José Jalife, have made a key discovery about cardiac arrhythmias in Andersen-Tawil syndrome (ATS)

Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
Research
23 Jan 2024

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis