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E.g., 01/10/2022
Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
Research
7 Jun 2021

A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart

Sara Martínez Martínez, María José Méndez Olivares, Álvaro Alfayate, , Andrea de la Fuente-Alonso,  Miguel R. Campanero, Juan Miguel Redondo y Jesús Vázquez.
Research
11 May 2021

Scientists at the CNIC and CSIC have shown that elevated activity of proteins regulated by nitric oxide (NO) causes the aortic disease seen in Marfan Syndrome patients

Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
About the CNIC
13 Apr 2021

The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy

Mª Ángeles Zuriaga, Mirian Díez, Fátima Sánchez-Cabo, Ana Dopazo, José Javier Fuster, Ana Quintas y Jorge de la Barrera.
Research
5 Apr 2021

The study, carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia, establishes clonal hematopoiesis as a new cardiovascular risk factor and an important link between aging and cardiovascular disease


Marta Amorós Pérez, Virginia Zorita, Nuria Matesanz, Marian Zuriaga y José Javier Fuster.
About the CNIC
23 Dec 2020

The project will investigate the role of clonal hematopoiesis—the formation of mutated hematopoietic stem-cell clones promoted by anti-cancer therapies—in the development of atherosclerosis and associated cardiovascular disease

Irene Fernández-Nueda, Carlos Cerón y Marta Cortés-Canteli
About the CNIC
15 Dec 2020

The BioClotAD project, coordinated by CNIC scientist Dr Marta Cortés Canteli, has been selected by the EU Joint Programme – Neurodegenerative Disease Research (JPND)


Jesús Vázquez, Almudena Ramiro, José Luis Martín Ventura, Inmaculada Martos Folgado, Cristina Lorenzo y Sonia Mur.
Research
2 Dec 2020

Un estudio que se publica en Nature muestra a la proteína mitocondrial ALDH4A1 como un nuevo autoantígeno implicado en los procesos de la aterosclerosis

Research
16 Oct 2020

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) review the roles of a groups of proteins called stress kinases in metabolism in an article published in Nature Reviews Endocrinology


Research
17 Sep 2020

The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes

Imágenes de las coroides de ratones control (izquierda) y tras la eliminación de IHH de las células endoteliales (derecha), lo que resulta en una disminución del número de mastocitos (puntos blancos).
Research
20 Mar 2020

Scientists at the CNIC and Weill Cornell Medicine have identified an inflammatory regulatory circuit controlled by a subtype of endothelial cells in the eye