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    E.g., 08/07/2025
    E.g., 08/07/2025
    Research
    6 Oct 2020
    JACC: Vigorous exercise, spongy heart

    CNIC scientists have shown that vigorous physical exercise is linked to "noncompaction" of the heart, causing it to acquire a spongy appearance.
    Research
    29 Sep 2020
    JACC: CNIC scientists design an algorithm for personalized cardiovascular risk estimation in healthy people

    The study, published in JACC, forms part of the PESA-CNIC-SANTANDER project, led by Dr Valentín Fuster
    Research
    17 Sep 2020
    Nature Metabolism: CNIC researchers discover a mechanism allowing immune cells to regulate obesity

    The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes
    Research
    16 Sep 2020
    Cell: CNIC researchers discover a cell-cleaning system that keeps hearts healthy

    The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart
    Research
    30 Jul 2020
    Nature: Scientists at the CNIC and IIS Princesa decipher a key mechanism in hypoxia

    The study, published in Nature, shows that sodium controls hypoxic signaling in the mitochondrial respiratory chain
    Research
    29 May 2020
    Alejandro Sánchez Alvarado: "The real magic is to imagine the experiment and execute it"

    The researcher Alejandro Sánchez Alvarado is one of the greatest experts in the study of the mechanisms involved, cellular and biological, in regeneration in the planaria model
    Research
    7 May 2020
    JACC: Blood Thinners may Improve Survival among Hospitalized Covid-19 Patients

    Research could change standard of care protocols to prevent clotting associated with coronavirus
    Research
    28 Apr 2020
    Nature Communications: CNIC scientists design an experimental mouse model for investigating the mechanical function of proteins in vivo

    CNIC scientists, working with international partners, have developed a new experimental mouse model that allows them to study how cells sense, interpret, and generate mechanical forces
    En la imagen se muestra con un asterisco la presencia de una placa de aterosclerosis avanzada en la carótida común detectada por la técnica de ecografía 3D que no llega a ocasionar una obstrucción significativa de la luz del vaso (es <50%). Se puede comprobar con precisión su extensión en las 3 dimensiones del espacio lo que nos permite detectar cambios en su volumen para determinar si existe un avance de la enfermedad.
    Research
    7 Apr 2020
    JACC: Atherosclerosis progresses rapidly in healthy people from the age of 40

    A CNIC study published in JACC demonstrates that atheroma plaques extend rapidly in the arteries of asymptomatic individuals aged between 40 and 50 years participating in the PESA-CNIC-Santander study.
    Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
    Research
    3 Apr 2020
    Nature Communications: CNIC scientists discover a new molecular mechanism that regulates the sentinel cells of the immune system

    Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR