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E.g., 27/06/2024
E.g., 27/06/2024
About the CNIC
15 May 2024

Globally, cardiovascular diseases due to atherosclerosis – the build-up of plaque in arteries – are the leading cause of death. A new Danish-Spanish research collaboration aims to develop methods to detect atherosclerosis at earlier ages and encourage prevention. Denmark’s Novo Nordisk Foundation has granted up to EUR 23 million to cover the first 2.5 years of the REACT initiative. The initiative is expected to run for 8 years in total


El Dr. Valentín Fuster con la Dra. Guiomar Mendieta
About the CNIC
10 Apr 2024

Guiomar Mendieta has been awarded the 2023 William W. Parmley Young Author Achievement Award for a paper published in JACC that is considered to an outstanding contribution in the field of atherosclerosis

Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
Research
23 Jan 2024

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis

Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
Research
20 Nov 2023

Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough

De izda. a dcha.: Gema González, Estefanía Núñez, Sergio Callejas, Juan Carlos Silla, Enrique Lara-Pezzi, Valentín Fuster, Fátima Sánchez Cabo, José Javier Fuster, Ana Dopazo, Borja Ibáñez, Marta Cortés, Alberto Benguría y Antonio Quesada.
Research
21 Jun 2023

A new CNIC study shows that low-grade systemic inflammation triggered by subcinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals

Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
Research
26 Jul 2022

Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals

Marta Cortés Canteli teams
About the CNIC
18 May 2022

The project will examine long-term changes in plasma biomarkers of neuronal injury, neuroinflammation, and Alzheimer's disease in participants in the PESA-CNIC-SANTANDER study who have undergone imaging studies to map brain metabolism. The goal of the project is to determine how cardiovascular risk factors during midlife impact brain function


. 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch.
Research
16 Mar 2022

Scientists at the CNIC have led the development of a new three dimensional ultrasound method that improves the assessment of cardiovascular risk in healthy individuals


Association between the level of glycosylated hemoglobin and the extent of subclinical atherosclerosis
Research
31 May 2021

In an article published in JACC, CNIC scientists report a method for improved ranking of cardiovascular risk in individuals without diabetes

3D images obtained in anatomical, functional, and tissue characterization studies performed with the ultrafast cardiac magnetic resonance protocol
Research
22 Apr 2021

Ultrafast cardiac magnetic resonance allows precise assessment of heart anatomy and function while reducing healthcare costs and increasing patient comfort