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    E.g., 31/08/2025
    E.g., 31/08/2025
    CNIC-led REBOOT clinical trial challenges 40-year-old standard of care for heart attack patients
    Research
    30 Aug 2025
    NEJM & The Lancet: CNIC-led REBOOT clinical trial challenges 40-year-old standard of care for heart attack patients

    REBOOT trial, coordinated by the CNIC, shows that treatment with beta-blockers provides no benefit to patients who experience an uncomplicated heart attack that leaves the contractile function of the heart intact.
    ESC Congress 2025
    About the CNIC
    30 Aug 2025
    EHJ: New study finds that, after a heart attack, women have worse prognosis when treated with beta-blockers

    The REBOOT study was presented during the European Society of Cardiology Congress (ESC Congress 2025) in Madrid
    ESC Congress 2025 CNIC
    About the CNIC
    26 Aug 2025
    The CNIC at the European Cardiology Congress 2025

    The European Society of Cardiology is holding its annual congress in Madrid from August 29 to September 1
    La investigadora Claudia Monaco
    Research
    1 Aug 2025
    Claudia Monaco: “We think we know a lot about cardiovascular disease, but in reality, we don't”

    Dr. Claudia Monaco, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK
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    Research
    16 Jul 2025
    Nature: A gut microbiota metabolite linked to atherosclerosis could revolutionise diagnosis and treatment

    A new study led by the CNIC has identified imidazole propionate (ImP), a metabolite produced by gut bacteria, as a driver of atherosclerosis— as a driver of atherosclerosis, the disease behind most heart attacks and strokes
    Marina Rosa Moreno, Fátima Sánchez Cabo, José Luis Cabrera, José Antonio Enríquez, María Concepción Jiménez, Pablo Hernansanz Agustín Lucía Sánchez-García.
    Research
    2 Jul 2025
    Cell Genomics: CNIC scientists reveal how the cellular energy system evolved—and how this knowledge could improve the diagnosis of rare genetic diseases

    CNIC researchers have uncovered the evolutionary logic of the OxPhos system—the cell’s “engine”—and developed a tool to detect mutations that cause mitochondrial disease
    Dr. Eduardo Marbán
    Research
    18 Jun 2025
    Eduardo Marbán: "We have designed a cellular product called Deramiocel, and until now, we have had positive results in at least two clinical trials"
    José Antonio Enríquez, Almudena Ramiro y Silvia Priori.
    About the CNIC
    17 Jun 2025
    Three CNIC projects receive more than €5 million in ERC Advanced Grant funding

    The projects—led by Drs Almudena Ramiro, José Antonio Enríquez, and Silvia Priori—will receive a total of €5.25 million for CNIC research over the next 5 years
    De izquierda a derecha y de arriba hacia abajo: Maria Rosaria Pricolo, Natalia Vicente, Verónica Labrador, Olga Giménez, Manuel Gavilán, Jon Sicilia, Jesús Vázquez, Elías Herrero, Roberto Silva, Jorge Alegre y Diana Velázquez.
    Research
    5 Jun 2025
    Nature Biomedical Engineering: A new method for studying mechanical proteins and their involvement in muscular disorders

    This new tool will advance the development of treatments for congenital muscle diseases and cardiomyopathies. 
    Sarai Martínez Cano, Marcos Femenía Muiña, Elena Hernández, Vanessa Núñez, Manuel Rodrigo Tapias, Miguel Galán Burgos, Iñaki Robles, Alberto Benguria, David Sancho y Almudena Ramiro
    Research
    2 Jun 2025
    Circulation Research: CNIC scientists uncover how the immune response drives atherosclerosis—the root cause of heart attacks and strokes

    A team from the CNIC has discovered the key role of conventional type 1 dendritic cells (cDC1) in atherosclerosis and has developed an experimental therapy with immunosuppressive nanoparticles that slows the progression of the disease in animal models.