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    E.g., 22/09/2026
    E.g., 22/09/2026
    Research
    11 Sep 2026
    JAHA: Two novel blood biomarkers predict subclinical atherosclerosis and cardiovascular events

    A new study, published in the Journal of the American Heart Association, shows that individuals with elevated levels of both proteins have twice the risk of cardiovascular events.
    Images show macrophages (green) in close association with fibroblasts (magenta).
    Research
    4 Sep 2026
    Science Immunology: Busy Tissues Need Bigger Cleanup Crews to Work at Their Best

    The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed.
    Robert E. Gerszten
    About the CNIC
    19 Jun 2026
    Robert E. Gerszten: "Blood is like a highway of information"
    Research
    14 Jan 2026
    European Heart Journal: Study reveals how high blood pressure increases susceptibility to heart damage caused by a key cancer treatment

    A CNIC research team has identified for the first time the biological mechanism underlying this susceptibility: high blood pressure creates a hidden metabolic vulnerability in the heart that becomes destabilized when anthracyclines are administered.
    Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
    Research
    19 Sep 2024
    JACC: Cardiovascular Imaging: Cardiometabolic risk factors in apparently healthy individuals are linked to altered coronary microcirculation

    A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk
    Dra. Hélène Girouard
    Research
    4 Aug 2024
    Dra. Hélène Girouard: “In alzheimer’s disease, high blood pressure is the main risk factor after age”

    Laboratory of Pharmacology and Physiology of the University of Montreal (Canadá)

    Rebecca F. Gottesman
    Research
    4 Jun 2024
    Rebecca F. Gottesman: “Telling someone their risk of dementia would drop if they treated their high blood pressure would impact them more than the possibility of a heart attack or stroke"

    Stroke Branch Chief at the National Institute of Neurological Disorders and Stroke (NINDS)
    Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
    Research
    20 Nov 2023
    JACC: Younger people are more vulnerable to the effects of cardiovascular risk associated with high blood cholesterol and hypertension

    Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough
    Research
    2 Oct 2023
    Diabetes Care: Obesity, high blood pressure, and lipid imbalance trigger a progressive loss of energy generation capacity in the heart

    Scientists at the CNIC have discovered that metabolic cardiovascular risk factors diminish the capacity of the heart to use glucose as an energy source
    Análisis de muestras humanas y experimentos en animales demuestran que la presencia de mutaciones en el gen p53 en sangre aumenta el riesgo de desarrollar aterosclerosis, la principal causa de enfermedad cardiovascular.
    Research
    16 Jan 2023
    Nature Cardiovascular Research: The 'guardian of the genome' protects against cardiovascular disease

    A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor