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iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function

Scientists at the CNIC, CIBER, and University of Berne identify the fundamental role of a family of proteins in an essential process for cellular energy production

The elimination of progerin from vascular smooth muscle cells, but not from endothelial cells, prevents the atherosclerosis associated with Hutchinson-Gilford progeria syndrome (HGPS)

The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity