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A team led by scientists at the CNIC and CSIC has found that accumulation of versican in the aortas of Marfan syndrome patients triggers the activation of the nitric oxide pathway through the activation of the the protein AKT

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances

Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

The Honorific Award for Excellence in Scientific Research is awarded in recognition of the career of scientists who have contributed to the generation of knowledge and advances in their field of specialization

Scientists at the CNIC and Hospital de la Princesa-UAM have identified profound changes taking place in dendritic cells during antigen presentation to a lymphocyte via intimate contact called an immune synapse

This disease, which can trigger sudden death in elite athletes, is caused by genetic mutations that affect proteins responsible for connecting and coordinating the muscle cells (myocytes) in the myocardium the heart’s muscular wall