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iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function

Scientists at the CNIC, CIBER, and University of Berne identify the fundamental role of a family of proteins in an essential process for cellular energy production

The results, published in JACC, suggest that these factors could be used to predict the risk of developing dilated cardiomyopathy and adapt strategies for patient care and disease detection in genetic carriers of the disease

The CNIC project will use innovative approaches to investigate cardiac regeneration

British Heart Foundation

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis