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This new tool will advance the development of treatments for congenital muscle diseases and cardiomyopathies. 

A team from the CNIC has discovered the key role of conventional type 1 dendritic cells (cDC1) in atherosclerosis and has developed an experimental therapy with immunosuppressive nanoparticles that slows the progression of the disease in animal models.

CNIC researchers have discovered that the heart is formed from two independent cell types that act in synchrony from the onset of gastrulation. This finding could help to better understand the origin of certain congenital heart defects and open up new opportunities in regenerative medicine and tissue bioengineering.

Dr. Mariell Jessup is Chief Science and Medical Officer of the American Heart Association

A CNIC team has developed an innovative gene therapy strategy for arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly inherited condition that particularly affects young men

Scientists at the CNIC and the University of Bern have found that heart surgery in male mice early in life creates a "memory" passed down to the next generation. Published in Circulation, the study suggests that a parental history of heart surgery should be considered when evaluating cardiovascular health in descendants.

The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure

Scientists at the CNIC have discovered how gut bacteria that cross a weakened intestinal barrier induce changes in bone marrow that strengthen the immune response