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E.g., 04/11/2026
E.g., 04/11/2026
Enrique_Lara_Cardiovascular_Research
About the CNIC
1 Oct 2026

The finding, published in Cardiovascular Research, lays the groundwork for specific treatments for heart failure with preserved ejection fraction

The R33Q mutation in calsequestrin 2 (CASQ2) disrupts calcium control in heart cells and activates protein-degradation mechanisms.
Research
23 Sep 2026

Researchers at the CNIC, in collaboration with the University of Pavia and IRCCS Istituti Clinici Scientifici Maugeri, have found that activation of the enzyme calpain contributes to the development of a severe inherited arrhythmia.

Research
11 Sep 2026

A new study, published in the Journal of the American Heart Association, shows that individuals with elevated levels of both proteins have twice the risk of cardiovascular events.

Images show macrophages (green) in close association with fibroblasts (magenta).
Research
4 Sep 2026

The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed.

William Joyce
About the CNIC
3 Sep 2026

TROPOSplice proposes an evolution-inspired strategy to improve cardiac relaxation in patients with hypertrophic cardiomyopathy and heart failure with preserved ejection fraction.

Research
2 Sep 2026

A new analysis of the DapaTAVI trial, published in the European Journal of Heart Failure, confirms that dapagliflozin improves outcomes after TAVI regardless of cardiac function.

Yolanda Martí-Mateos, José Antonio Enríquez y Rebeca Acín-Pérez.
Research
6 Aug 2026

The protein, OMA1, delays immune-system overactivation, liver fibrosis, and liver cancer during aging

Pablo García Pavía y Nerea Mora.
Research
4 Aug 2026

Left ventricular hypertrabeculation, an anatomical feature of the heart traditionally linked to higher risk, does not worsen outcomes in patients with dilated cardiomyopathy

eLife
About the CNIC
21 Jul 2026

The study reveals that the early heart is shaped by distinct but closely coordinated patterns of tissue deformation 

Diana Velázquez, Natalia Vicente, Jon Sicilia, María Rosaria Pricolo, Laura Sen, Jorge Alegre y Agata Bak.
Research
7 Jul 2026

Hypertrophic cardiomyopathy is the most common inherited heart disease and the leading cause of sudden cardiac death in young people and athletes