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E.g., 09/07/2025
E.g., 09/07/2025
Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
Research
1 Feb 2024

A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs


Ayelén M. Santamans y Guadalupe Sabio
Research
19 Jan 2024

A team led by scientists from the CNIC and CNIO has identified a potential therapeutic target that protects the heart in patients with pulmonary hypertension

Edward Pearce
Research
21 Dec 2023

Johns Hopkins UniversityBloomberg School of Public HealthBaltimore

Marcos Siguero Álvarez, Luis Luna Zurita, José Luis de la Pompa y Brenda Giselle Flores Garza
Research
11 Dec 2023

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances


Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
Research
10 Nov 2023

Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

Dr. Fuster
De izquierda a derecha: Cristina Sanchez-Ramos, Nieves Garcia-Quintans, David Morera, Mariya Lytvyn, Juan A Bernal, Mª Ángeles Sanguino, Daniel Martín Perez, Fernando de Benito, David Sanz y Emilio Camafeita
Research
23 Oct 2023

This disease, which can trigger sudden death in elite athletes, is caused by genetic mutations that affect proteins responsible for connecting and coordinating the muscle cells (myocytes) in the myocardium the heart’s muscular wall

Research
2 Oct 2023

Scientists at the CNIC have discovered that metabolic cardiovascular risk factors diminish the capacity of the heart to use glucose as an energy source

Rebeca Piñeiro-Sabarís, Marcos Siguero-Álvarez, Donald McGrogan y José Luis de la Pompa.
Research
5 Jul 2023

A multicenter study published in JAMA Cardiology and co-led by scientists at Hadassah Medical Center, Sheba Medical Center, and the CNIC could help in the design of future pharmacological treatments for bicuspid aortic valve