Selected publications

Cruz FM, Sanz-Rosa D, Roche-Molina M, Garcia-Prieto J, Garcia-Ruiz JM, Pizarro G, Jimenez-Borreguero LJ, Torres M, Bernad A, Ruiz-Cabello J, Fuster V, Ibanez B and Bernal JA. Exercise Triggers ARVC Phenotype in Mice Expressing a Disease-Causing Mutated Version of Human Plakophilin-2 J Am Coll Cardiol (2015) 65:1438-50
Roche-Molina M, Sanz-Rosa D, Cruz FM, Garcia-Prieto J, Lopez S, Abia R, Muriana FJ, Fuster V, Ibanez B, Bernal JA Induction of Sustained Hypercholesterolemia by Single Adeno-Associated Virus-Mediated Gene Transfer of Mutant hPCSK9 Arterioscler Thromb Vasc Biol (2015) 35:50-9
Nagasawa S, Sedukhina AS, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, Tsugawa K, Ohta T, Roche-Molina M, Bernal JA, Narvaez AJ, Jeyasekharan AD, Sato K LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition PLoS One (2015) 10:e0118002
Link to the full text in Repisalud
Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narvaez AJ, Jeyasekharan AD, Bernal JA, Sato K NF-kB signaling mediates acquired resistance after PARP inhibition Oncotarget (2015) 6:3825-39
Link to the full text in Repisalud
Pimentel B, Nair R, Bermejo-Rodriguez C, Preston MA, Agu CA, Wang X, Bernal JA, Sherratt DJ and de la Cueva-Mendez G. Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells. Proc Natl Acad Sci U S A (2014) 111:2734-9
Garcia-Prieto J, Garcia-Ruiz JM, Sanz-Rosa D, Pun A, Garcia-Alvarez A, Davidson SM, Fernandez-Friera L, Nuno-Ayala M, Fernandez-Jimenez R, Bernal JA, Izquierdo-Garcia JL, Jimenez-Borreguero J, Pizarro G, Ruiz-Cabello J, Macaya C, Fuster V, Yellon DM, Ibanez B beta adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes Basic Res Cardiol (2014) 109:422
Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR. HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response Nature (2008) 453:682-6
Su X, Bernal JA, Venkitaraman AR. Cell-cycle coordination between DNA replication and recombination revealed by a vertebrate N-end rule degron-Rad51 Nat Struct Mol Biol (2008) 15:1049-58
Bernal JA, Roche M, Méndez-Vidal C, Espina A, Tortolero M, Pintor-Toro JA. Proliferative potential after DNA damage and non-homologous end joining are affected by loss of securin Cell Death Differ (2008) 15:202-12
Sangrithi MN, Bernal JA, Madine M, Philpott A, Lee J, Dunphy WG, Venkitaraman AR. Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome. Cell (2005) 121:887-98
Bernal JA, Luna R, Espina A, Lázaro I, Ramos-Morales F, Romero F, Arias C, Silva A, Tortolero M, Pintor-Toro JA. Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis Nat Genet (2002) 32:306-11