Selected publications

Vicanolo T, Özcan A, Li JL, Huerta-López C, Ballesteros I, Rubio-Ponce A, Dumitru AC, Nicolás-Ávila JÁ, Molina-Moreno M, Reyes-Gutierrez P, Johnston AD, Martone C, Greto E, Quílez-Alvarez A, Calvo E, Bonzon-Kulichenko E, Álvarez-Velez R, Chooi MY, Kwok I, González-Bermúdez B, Malleret B, Espinosa FM, Zhang M, Wang YL, Sun D, Zhen Chong S, El-Armouche A, Kim KK, Udalova IA, Greco V, Garcia R, Vázquez J, Dopazo A, Plaza GR, Alegre-Cebollada J, Uderhardt S, Ng LG, Hidalgo A. Matrix-producing neutrophils populate and shield the skin. Nature (2025) 641:740-748

Schoofs H, Daubel N, Schnabellehner S, Grönloh MLB, Palacios Martínez S, Halme A, Marks AM, Jeansson M, Barcos S, Brakebusch C, Benedito R, Engelhardt B, Vestweber D, Gaengel K, Linsenmeier F, Schürmann S, Saharinen P, van Buul JD, Friedrich O, Smith RS, Majda M, Mäkinen T. Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium Nature (2025) Mar 27 [Epub ahead of print]
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de la Pompa JL. Tunneling through cardiac jelly. Science (2025) 387:1151-1152

Gómez de Cedrón M, Moreno-Rubio J, de la O Pascual V, Alvarez B, Villarino M, Sereno M, Gómez-Raposo C, Roa S, López Gómez M, Merino-Salvador M, Jiménez Gordo A, Falagán S, Aguayo C, Zambrana F, Tabarés B, Garrido B, Cruz-Gil S, Fernández Díaz CM, Fernández LP, Molina S, Crespo MC, Ouahid Y, Montoya JJ, Ramos Ruíz R, Reglero G, Ramírez de Molina A, Casado E. Randomized clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits Front Immunol (2025) 16
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Trerotola M, Relli V, Tripaldi R, Simeone P, Guerra E, Sacchetti A, Ceci M, Pantalone L, Ciufici P, Moschella A, Caiolfa VR, Zamai M, Alberti S. Large, recursive membrane platforms are associated to Trop-1, Trop-2, and protein kinase signaling for cell growth. Mol Biol Cell (2025) 36:ar38

Soto-Heredero G, Gabandé-Rodríguez E, Carrasco E, Escrig-Larena JI, Gómez de Las Heras MM, Delgado-Pulido S, Francos-Quijorna I, Blanco EM, Fernández-Almeida Á, Abia D, Rodríguez MJ, Fernández-Díaz CM, Álvarez-Flores MB, Ramírez de Molina A, Jung S, Del Sol A, Zorita V, Sánchez-Cabo F, Torroja C, Mittelbrunn M. KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging. Nat Aging (2025) 5:799-815

Silva-Rojas R, Vicente N, Gavilán-Herrera M, Labrador-Cantarero V, Sicilia J, Giménez-Sáez O, Dumitru AC, Sánchez MI, Gato-Vilaseca M, Velázquez-Carreras D, López JA, Vázquez J, Herrero-Galán E, López-Unzu MA, Pricolo MR, Alegre-Cebollada J. Mechanically knocking out titin reveals protein tension loss as a trigger of muscle disease. Nat Biomed Eng (2025) :1-34

Hernansanz-Agustín P, Morales-Vidal C, Calvo E, Natale P, Martí-Mateos Y, Jaroszewicz SN, Cabrera-Alarcón JL, Acín-Pérez R, López-Montero I, Vázquez J, Enríquez JA. A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria. Cell (2024) 187:6599-6613
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Díez-Díez M, Ramos-Neble BL, de la Barrera J, Silla-Castro JC, Quintas A, Vázquez E, Rey-Martín MA, Izzi B, Sánchez-García L, García-Lunar I, Mendieta G, Mass V, Gómez-López N, Espadas C, González G, Quesada AJ, García-Álvarez A, Fernández-Ortiz A, Lara-Pezzi E, Dopazo A, Sánchez-Cabo F, Ibáñez B, Andrés V, Fuster V, Fuster JJ. Unidirectional association of clonal hematopoiesis with atherosclerosis development. Nat Med (2024) 30:2857-2866
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Garcia-Gonzalez I, Gambera S, Rocha SF, Regano A, Garcia-Ortega L, Lytvyn M, Diago-Domingo L, Sanchez-Muñoz MS, Garcia-Cabero A, Zagorac I, Luo W, De Andrés-Laguillo M, Fernández-Chacón M, Casquero-Garcia V, Lunella FF, Torroja C, Sánchez-Cabo F, Benedito R. iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells. Nat Methods (2024) 22:323-334
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Zuriaga MA, Yu Z, Matesanz N, Truong B, Ramos-Neble BL, Asensio-López MC, Uddin MM, Nakao T, Niroula A, Zorita V, Amorós-Pérez M, Moro R, Ebert BL, Honigberg MC, Pascual-Figal D, Natarajan P, Fuster JJ. Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis. 10.1093/eurheartj/ehae546. Eur Heart J (2024) 45:4601-4615
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Hamczyk MR*, Nevado RM, Gonzalo P, Andrés-Manzano MJ, Nogales P, Quesada V, Rosado A, Torroja C, Sánchez-Cabo F, Dopazo A, Bentzon JF, López-Otín C, Andrés V*. *co-corresponding authors. Endothelial-to-Mesenchymal Transition Contributes to Accelerated Atherosclerosis in Hutchinson-Gilford Progeria Syndrome. doi: 10.1161/CIRCULATIONAHA.123.065768 Circulation (2024) 150:1612-1630.

Santos-Beneit G, Bodega P, de Cos-Gandoy A, de Miguel M, Rodríguez C, Orrit X, Carral V, Haro D, Carvajal I, Peyra C, Martínez-Gómez J, Fernández-Alvira JM, Fernández-Jiménez R, Fuster V. Effect of Time-Varying Exposure to School-Based Health Promotion on Adiposity in Childhood. J Am Coll Cardiol (2024) 84:499-508.

Fuster V, García-Álvarez A, Devesa A, Mass V, Owen R, Quesada A, Fuster JJ, García-Lunar I, Pocock S, Sánchez-González J, Sartori S, Peyra C, Andres V, Muntendam P, Ibanez B. Influence of Subclinical Atherosclerosis Burden and Progression on Mortality. J Am Coll Cardiol (2024) 84:1391-1403
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Toribio-Fernández R, Tristão-Pereira C, Carlos Silla-Castro J, Callejas S, Oliva B, Fernandez-Nueda I, Garcia-Lunar I, Perez-Herreras C, María Ordovás J, Martin P, Blanco-Kelly F, Ayuso C, Lara-Pezzi E, Fernandez-Ortiz A, Garcia-Alvarez A, Dopazo A, Sanchez-Cabo F, Ibanez B, Cortes-Canteli M, Fuster V. Apolipoprotein E-ε2 and Resistance to Atherosclerosis in Midlife: The PESA Observational Study Circ Res (2024) 134:411-424.
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Cruz FM, Macías Á, Moreno-Manuel AI, Gutiérrez LK, Vera-Pedrosa ML, Martínez-Carrascoso I, Sánchez Pérez P, Ruiz Robles JM, Bermúdez-Jiménez FJ, Díaz-Agustín A, Martínez de Benito F, Arias-Santiago S, Braza-Boils A, Martín-Martínez M, Gutierrez-Rodríguez M, Bernal JA, Zorio E, Jiménez-Jaimez J, Jalife J. Extracellular Kir2.1C122Y Mutant Upsets Kir2.1-PIP2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome Circ Res (2024) 134:e52-e71.

Zeng Q, Oliva VM, Moro MÁ, Scheiermann C. Circadian Effects on Vascular Immunopathologies. Circ Res (2024) 134:791-809.
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Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I*, Andrés V*. *co-corresponding authors. Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome. J Clin Invest (2024) 134:e173448
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Gómez-Del Arco P, Isern J, Jimenez-Carretero D, López-Maderuelo D, Piñeiro-Sabarís R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terrén M, Benguria A, Simón-Chica A, Queiro-Palou A, Dopazo A, Sánchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Muñoz-Cánoves P, Redondo JM. he G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun (2024) 15:8602
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Li-Bao L, Díaz-Díaz C, Raiola M, Sierra R, Temiño S, Moya FJ, Rodriguez-Perales S, Santos E, Giovinazzo G, Bleckwehl T, Rada-Iglesias Á, Spitz F, Torres M. Regulation of Myc transcription by an enhancer cluster dedicated to pluripotency and early embryonic expression. Nat Commun (2024) 15:3931.
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Aboy-Pardal MCM, Guadamillas MC, Guerrero CR, Català-Montoro M, Toledano-Donado M, Terrés-Domínguez S, Pavón DM, Jiménez-Jiménez V, Jimenez-Carretero D, Zamai M, Folgueira C, Cerezo A, Lolo FN, Nogueiras R, Sabio G, Sánchez-Álvarez M, Echarri A, Garcia R, Del Pozo MA. Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability. Nat Commun (2024) 15:10102
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Thambyrajah R, Maqueda M, Neo WH, Imbach K, Guillén Y, Grases D, Fadlullah Z, Gambera S, Matteini F, Wang X, Calero-Nieto FJ, Esteller M, Florian MC, Porta E, Benedito R, Göttgens B, Lacaud G, Espinosa L, Bigas A. Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate. Nat Commun (2024) 15:1604
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Rodriguez JM, Abascal F, Cerdán-Vélez D, Gómez LM, Vázquez J, Tress ML. Evidence for widespread translation of 5' untranslated regions Nucleic Acids Res (2024) 52:8112–8126
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Garcia-Gonzalez I, Rocha SF, Hamidi A, Garcia-Ortega L, Regano A, Sanchez-Muñoz MS, Lytvyn M, Garcia-Cabero A, Roig-Soucase S, Schoofs H, Castro M, Sabata H, Potente M, Graupera M, Makinen T, Benedito R. iSuRe-HadCre is an essential tool for effective conditional genetics. Nucleic Acids Res (2024) 52:gkae472
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Devesa A, Fuster V, García-Lunar I, Oliva B, García-Alvarez A, Moreno-Arciniegas A, Vazirani R, Pérez-Herreras C, Marina P, Bueno H, Fernández-Friera L, Fernández-Ortiz A, Sanchez-Gonzalez J, Ibanez B. Coronary Microvascular Function in Asymptomatic Middle-Aged Individuals With Cardiometabolic Risk Factors. JACC Cardiovasc Imaging (2024) 18:48-58
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Trivieri MG, Robson PM, Vergani V, LaRocca G, Romero-Daza AM, Abgral R, Devesa A, Azoulay LD, Karakatsanis NA, Parikh A, Panagiota C, Palmisano A, DePalo L, Chang HL, Rothstein JH, Fayad RA, Miller MA, Fuster V, Narula J, Dweck MR, Morgenthau A, Jacobi A, Padilla M, Kovacic JC, Fayad ZA. Hybrid Magnetic Resonance Positron Emission Tomography Is Associated With Cardiac-Related Outcomes in Cardiac Sarcoidosis. JACC Cardiovasc Imaging (2024) 17:411-424

Wculek SK, Forisch S, Miguel V, Sancho D. Metabolic homeostasis of tissue macrophages across the lifespan. Trends Endocrinol Metab (2024) S1043-2760:00111-5

Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells. doi:10.1073/pnas.2400752121. Proc Natl Acad Sci U S A (2024) 121:e2400752121
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García-Poyatos C, Arora P, Calvo E, Marques IJ, Kirschke N, Galardi-Castilla M, Lembke C, Meer M, Fernández-Montes P, Ernst A, Haberthür D, Hlushchuk R, Vázquez J, Vermathen P, Enríquez JA, Mercader N. Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization. Dev Cell (2024) S1534-5807:00237-5
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Valverde-Lopez JA, Li-Bao L, Sierra R, Santos E, Giovinazzo G, Díaz-Díaz C, Torres M. P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in pluripotent cell competition. PLoS Genet (2024) 20:e1011193
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Devesa A, Rashed E, Moss N, Robson PM, Pyzik R, Roldan J, Taimur S, Rana MM, Ashley K, Young A, Patel G, Mahmood K, Mitter SS, Lala A, Barghash M, Fox A, Correa A, Pirlamarla P, Contreras J, Parikh A, Mancini D, Jacobi A, Ghesani N, Gavane SC, Ghesani M, Itagaki S, Anyanwu A, Fayad ZA, Trivieri MG. 18F-FDG PET/CT in left ventricular assist device infections: In-depth characterization and clinical implications J Heart Lung Transplant (2024) 43:529-538

Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO Rep (2024) 25:2635-2661.

Rodrigo-Muñoz JM, Naharro-González S, Callejas S, Relaño-Ruperez C, Torroja C, Benguria A, Lorente-Sorolla C, Gil-Martínez M, García de Castro Z, Cañas JA, Valverde-Monge M, Bernaola J, Pinillos-Robles EJ, Betancor D, Fernández-Nieto M, Dopazo A, Sánchez-Cabo F, Sánchez-Pernaute O, Rodríguez-Nieto MJ, Sastre J, Del Pozo V. Single-cell RNA sequencing of human blood eosinophils reveals plasticity and absence of canonical cell subsets. ALLERGY (2024) 80:570-574

Semerano A, Fernández-Ruiz J, Cortes-Canteli M, Moro MA. From Alzheimer's disease to vascular dementia: Different roads leading to cognitive decline. Br J Pharmacol (2024) 181:755-759
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Villalba-Orero M, López-Olañeta M, Campos-Olmo B, Jimenez-Carretero D, Sánchez L, Sánchez-Cabo F, Ausiello A, Cañas-Álvaro R, Camafeita E, Vázquez J, García-Pavía P, Pascual-Figal D, Lara-Pezzi E. Unraveling Comorbidities Contribution to Cardiac Diastolic Dysfunction and Heart Failure. Circ Heart Fail (2024) :e011724

Di G, Vazquez S, Díaz B, Peña-Martinez C, García-Culebras A, Cuartero MI, Moraga A, Pradillo JM, Esposito E, Lo EH, Moro MA*, Lizasoain I* Daytime DNase-I administration protects mice from ischemic stroke without inducing bleeding or tPA-induced hemorrhagic transformation, even with aspirin pretreatment. Stroke (2024) 56:527-532

Devesa A, Robson PM, Cangut B, Vazirani R, Vergani V, LaRocca G, Romero-Daza AM, Liao S, Azoulay LD, Pyzik R, Fayad RA, Jacobi A, Abgral R, Morgenthau AS, Miller MA, Fayad ZA, Trivieri MG. Specific locations of myocardial inflammation and fibrosis are associated with higher risk of events in cardiac sarcoidosis. Heart Rhythm (2024) S1547-5271:03301-0

Pérez-García CN, García-Lunar I. Everything flows, nothing stays.. or does it? Rev Esp Cardiol (2024) S1885-5857:00244-5

Álvarez Flores MB, Sopeña Corvinos M, Guillén Santos R, Cava Valenciano F. Fluorescent Aerolysin (FLAER) Binding Is Abnormally Low in the Clonal Precursors of Acute Leukemias, with Binding Particularly Low or Absent in Acute Promyelocytic Leukemia. Int J Mol Sci (2024) 25:11898.

Piñeiro-Sabarís R, MacGrogan D, de la Pompa JL. Deficient GATA6-CXCR7 signaling leads to bicuspid aortic valve. Dis Model Mech (2024) 17:dmm050934
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Henderson DJ, Alqahtani A, Chaudhry B, Cook A, Eley L, Houyel L, Hughes M, Keavney B, de la Pompa JL, Sled J, Spielmann N, Teboul L, Zaffran S, Mill P, Liu KJ. Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping. Dis Model Mech (2024) 17:050913
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Piñeiro-Sabarís R, MacGrogan D, de la Pompa JL. Deficient GATA6-CXCR7 signaling leads to bicuspid aortic valve. Dis Model Mech (2024) 17:dmm050934
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Martínez-Gómez J, de Cos-Gandoy A, Fernández-Alvira JM, Bodega P, de Miguel M, Tresserra-Rimbau A, Laveriano-Santos EP, Ramirez-Garza SL, Orrit X, Carvajal I, Estruch R, Lamuela-Raventós RM, Santos-Beneit G, Fuster V, Fernández-Jiménez R. Cardiovascular Health Trajectories in Adolescence and Their Association With Sociodemographic and Cardiometabolic Outcomes in Spain. J ADOLESCENT HEALTH (2024) 74:1039-1048

Álvarez Flores MB, Sopeña Corvinos M, Guillén Santos R, Cava Valenciano F. High-Sensitivity Flow Cytometry for the Reliable Detection of Measurable Residual Disease in Hematological Malignancies in Clinical Laboratories. Diseases (2024) 12:338
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Carramolino L, Albarrán-Juárez J, Markov A, Hernández-SanMiguel E, Sharysh D, Cumbicus V, Morales-Cano D, Labrador-Cantarero V, Loof Møller P, Nogales P, Benguria A, Dopazo A, Sanchez-Cabo F, Torroja C, Bentzon JF. Cholesterol lowering depletes atherosclerotic lesions of smooth muscle cell-derived fibromyocytes and chondromyocytes. Nature Cardiovascular Research (2024) 3:203-220.

Orsi A, van Anken E, Vitale M, Zamai M, Caiolfa VR, Sitia R, Bakunts A. Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity. Life Sci Alliance (2024) 7:e202302562
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Dou W, Shan G, Zhao Q, Malhi M, Jiang A, Zhang Z, González-Guerra A, Fu S, Law J, Hamilton RM, Bernal JA, Liu X, Sun Y, Maynes JT. Robotic manipulation of cardiomyocytes to identify gap junction modifiers for arrhythmogenic cardiomyopathy. Sci Robot (2024) 9:eadm8233

Huerta-López C, Clemente-Manteca A, Velázquez-Carreras D, Espinosa FM, Sanchez JG, Martínez-Del-Pozo Á, García-García M, Martín-Colomo S, Rodríguez-Blanco A, Esteban-González R, Martín-Zamora FM, Gutierrez-Rus LI, Garcia R, Roca-Cusachs P, Elosegui-Artola A, Del Pozo MA, Herrero-Galán E, Sáez P, Plaza GR, Alegre-Cebollada J. Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing, Sci Adv (2024) 10:eadf9758

Musigk N, Suwalski P, Golpour A, Fairweather D, Klingel K, Martin P, Frustaci A, Cooper LT, Lüscher TF, Landmesser U, Heidecker B. The inflammatory spectrum of cardiomyopathies. Front Cardiovasc Med (2024) 11:1251780.
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Martín P. BMP4 mediates myocardial inflammation and fibrosis. Nature Cardiovascular Research (2024) 3:251-253

Heras-Murillo I, Adán-Barrientos I, Galán M, Wculek SK, Sancho D. Dendritic cells as orchestrators of anticancer immunity and immunotherapy. Nat Rev Clin Oncol (2024) 21:257-277

Binek A, Castans C, Jorge I, Bagwan N, Rodríguez JM, Fernández-Jiménez R, Galán-Arriola C, Oliver E, Gómez M, Clemente-Moragón A, Ibanez B, Camafeita E, Vázquez J. Oxidative Post-translational Protein Modifications upon Ischemia/Reperfusion Injury Antioxidants (2024) 13:106
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Martín P. BMP4 mediates myocardial inflammation and fibrosis. Nature Cardiovascular Research (2024) 3:251-253

Heras-Murillo I, Adán-Barrientos I, Galán M, Wculek SK, Sancho D. Dendritic cells as orchestrators of anticancer immunity and immunotherapy. Nat Rev Clin Oncol (2024) 21:257-277

Toner YC, Prévot G, van Leent MMT, Munitz J, Oosterwijk R, Verschuur AVD, van Elsas Y, Peric V, Maas RJF, Ranzenigo A, Morla-Folch J, Wang W, Umali M, de Dreu A, Fernandes JC, Sullivan NAT, Maier A, Mason C, Reiner T, Fayad ZA, Mulder WJM, Teunissen AJP, Pérez-Medina C. Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer. Npj Imaging (2024) 2:12
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Fernández-Friera L, García-Alvarez A, Oliva B, García-Lunar I, García I, Moreno-Arciniegas A, Gómez-Talavera S, Pérez-Herreras C, Sánchez-González J, de Vega VM, Rossello X, Bueno H, Fernández-Ortiz A, Ibañez B, Sanz J, Fuster V. Association between subclinical atherosclerosis burden and unrecognized myocardial infarction detected by cardiac magnetic resonance in middle-aged adults. Eur Heart J Cardiovasc Imaging (2024) 25:968-975
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Paredes A, Justo-Méndez R, Jiménez-Blasco D, Núñez V, Calero I, Villalba-Orero M, Alegre-Martí A, Fischer T, Gradillas A, Sant'Anna VAR, Were F, Huang Z, Hernansanz-Agustín P, Contreras C, Martínez F, Camafeita E, Vázquez J, Ruiz-Cabello J, Area-Gómez E, Sánchez-Cabo F, Treuter E, Bolaños JP, Estébanez-Perpiñá E, Rupérez FJ, Barbas C, Enríquez JA, Ricote M. gamma-Linolenic acid in maternal milk drives cardiac metabolic maturation. Nature (2023) 618:365-373
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Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, Andrés E, An J, Segalés J, Ortet L, Lukesova V, Volpe G, Benguria A, Dopazo A, Benitah SA, Urano Y, Del Sol A, Esteban MA, Ohkawa Y, Serrano AL, Perdiguero E, Muñoz-Cánoves P. Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. Erratum for: Nature. 2023 Jan;613(7942):169-178. PMID: 36747036 Nature (2023) 613:169-178
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Sánchez-Cabo F, Fuster V, Silla-Castro JC, González G, Lorenzo-Vivas E, Alvarez R, Callejas S, Benguría A, Gil E, Núñez E, Oliva B, Mendiguren JM, Cortes-Canteli M, Bueno H, Andrés V, Ordovás JM, Fernández-Friera L, Quesada AJ, Garcia JM, Rossello X, Vázquez J, Dopazo A, Fernández-Ortiz A, Ibáñez B, Fuster JJ, Lara-Pezzi E. Subclinical atherosclerosis and accelerated epigenetic age mediated by inflammation: a multi-omics study. Eur Heart J (2023) 4:2698-2709
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Garcia-Lunar I, Ibanez B, Fuster V. Motivational interview and imaging of subclinical atherosclerosis for cardiovascular disease prevention: a winning combination? Eur Heart J (2023) 44:1575-1576
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Siguero-Álvarez M, Salguero-Jiménez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sánchez-Sáez F, Piñeiro-Sabarís R, Felipe-Medina N, Torroja C, José Gómez M, Sabater-Molina M, Escribá R, Richaud-Patin I, Iglesias-García O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibañez B, Monserrat L, María Pérez-Pomares J, Sánchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL. A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation (2023) 147:47-65
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Aix E, Gallinat A, Yago-Díez C, Lucas J, Gómez MJ, Benguría A, Freitag P, Cortez-Toledo E, Fernández de Manuel L, García-Cuasimodo L, Sánchez-Iranzo H, Montoya MC, Dopazo A, Sánchez-Cabo F, Mercader N, López JE, Fleischmann BK, Hesse M, Flores I. Telomeres Fuse During Cardiomyocyte Maturation. Circulation (2023) 147:1634-1636
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Domínguez F, Lalaguna L, Martínez-Martín I, Piqueras-Flores J, Rasmussen TB, Zorio E, Giovinazzo G, Prados B, Ochoa JP, Bornstein B, González-López E, Velázquez-Carreras D, Pricolo MR, Gutiérrez-Agüera F, Bernal JA, Herrero-Galán E, Alegre-Cebollada J, Lara-Pezzi E, García-Pavía P. Titin Missense Variants as a Cause of Familial Dilated Cardiomyopathy. Circulation (2023) 147:1711-1713
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Wculek SK, Heras-Murillo I, Mastrangelo A, Mañanes D, Galán M, Miguel V, Curtabbi A, Barbas C, Chandel NS, Enríquez JA, Lamas S, Sancho D. Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis. Immunity (2023) 56:516-530.e9
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Devesa A, Lobo-González M, Martínez-Milla J, Oliva B, García-Lunar I, Mastrangelo A, España S, Sanz J, Mendiguren JM, Bueno H, Fuster JJ, Andrés V, Fernández-Ortiz A, Sancho D, Fernández-Friera L, Sanchez-Gonzalez J, Rossello X, Ibanez B, Fuster V. Bone marrow activation in response to metabolic syndrome and early atherosclerosis. Eur Heart J (2022) 43:1809-1828
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Martin P, Blanco-Dominguez R, Sanchez-Diaz R Novel human immunomodulatory T cell receptors and their double-edged potential in autoimmunity, cardiovascular disease and cancer Cell Mol Immunol (2020) 18:919-35

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Garcia-Gonzalez I, Mühleder S, Fernández-Chacón M, Benedito R Genetic Tools to Study Cardiovascular Biology Front Physiol (2020) 11:1084
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Tsilingiri K, de la Fuente H, Relano M, Sanchez-Diaz R, Rodriguez C, Crespo J, Sanchez-Cabo F, Dopazo A, Alonso-Lebrero JL, Vara A, Vazquez J, Casasnovas JM, Alfonso F, Ibanez B, Fuster V, Martinez-Gonzalez J, Martin P*, Sanchez-Madrid F*. (PM and FSM are co-corresponding authors) oxLDL Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease. Circulation (2019) 139:243-55
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Padron-Barthe L, Villalba-Orero M, Gomez-Salinero JM, Dominguez F, Roman M, Larrasa-Alonso J, Ortiz-Sanchez P, Martinez F, Lopez-Olaneta M, Bonzon-Kulichenko E, Vazquez J, Marti-Gomez C, Santiago DJ, Prados B, Giovinazzo G, Gomez-Gaviro MV, Priori S, Garcia-Pavia P, Lara-Pezzi E Severe Cardiac Dysfunction and Death Caused by Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Are Improved by Inhibition of Glycogen Synthase Kinase-3beta Circulation (2019) 140:1188-1204
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Garcia-Pavia P, Kim Y, Alejandra Restrepo-Cordoba M, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nunez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, Baksi AJ, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE Genetic Variants Associated with Cancer Therapy-Induced Cardiomyopathy Circulation (2019) 140:31-41
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Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hamalainen RH, Pellico J, Justo-Mendez R, Fernandez-Toro JM, Claveria C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruiz-Cabello J, Enriquez JA Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy Cell Metab (2019) 30:1120-30
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Adrover JM, del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity (2019) 50:390-402
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Martínez-López M, Iborra S, Conde-Garrosa R, Mastrangelo A, Danne C, Mann ER, Reid DM, Gaboriau-Routhiau V, Chaparro M, Lorenzo MP, Minnerup L, Saz-Leal P, Slack E, Kemp B, Gisbert JP, Dzionek A, Robinson MJ, Rupérez FJ, Cerf-Bensussan N, Brown GD, Bernardo D, LeibundGut-Landmann S, Sancho D. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity (2019) 50:446-61
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Santos-Lozano A, Fiuza-Luces C, Fernandez-Moreno D, Llavero F, Arenas J, Lopez JA, Vazquez J, Escribano-Subias P, Zugaza JL, Lucia A Exercise Benefits in Pulmonary Hypertension J Am Coll Cardiol (2019) 73:2906-7
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Cortes-Canteli M, Kruyer A, Fernandez-Nueda I, Marcos-Diaz A, Ceron C, Richards AT, Jno-Charles OC, Rodriguez I, Callejas S, Norris EH, Sanchez-Gonzalez J, Ruiz-Cabello J, Ibanez B, Strickland S, Fuster V Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model J Am Coll Cardiol (2019) 74:1910-23
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Galán-Arriola C, Lobo M, Vílchez-Tschischke JP, López GJ, de Molina-Iracheta A, Pérez-Martínez C, Agüero J, Fernández-Jiménez R, Martín-García A, Oliver E, Villena-Gutierrez R, Pizarro G, Sánchez PL, Fuster V, Sánchez-González J, Ibanez B. Serial Magnetic Resonance Imaging to Identify Early Stages of Anthracycline-Induced Cardiotoxicity. J Am Coll Cardiol (2019) 73:779-91
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Ibanez B, Aletras AH, Arai AE, Arheden H, Bax J, Berry C, Bucciarelli-Ducci C, Croisille P, Dall'Armellina E, Dharmakumar R, Eitel I, Fernandez-Jimenez R, Friedrich MG, Garcia-Dorado D, Hausenloy DJ, Kim RJ, Kozerke S, Kramer CM, Salerno M, Sanchez-Gonzalez J, Sanz J, Fuster V. Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel. J Am Coll Cardiol (2019) 74:238-256
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Al-Mashhadi RH, Tolbod LP, Bloch LO, Bjorklund MM, Nasr ZP, Al-Mashhadi Z, Winterdahl M, Frokiaer J, Falk E, Bentzon JF (18)Fluorodeoxyglucose Accumulation in Arterial Tissues Determined by PET Signal Analysis J Am Coll Cardiol (2019) 74:1220-32
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Fernandez-Jimenez R, Jaslow R, Bansilal S, Santana M, Diaz-Munoz R, Latina J, Soto AV, Vedanthan R, Al-Kazaz M, Giannarelli C, Kovacic JC, Bagiella E, Kasarskis A, Fayad ZA, Hajjar RJ, Fuster V Child Health Promotion in Underserved Communities: The FAMILIA Trial J Am Coll Cardiol (2019) 73:2011-21
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Quintanilla JG, Alfonso-Almazan JM, Perez-Castellano N, Pandit SV, Jalife J, Perez-Villacastin J, Filgueiras-Rama D Instantaneous Amplitude and Frequency Modulations Detect The Footprint of Rotational Activity and Reveal Stable Driver Regions as Targets for Persistent Atrial Fibrillation Ablation Circ Res (2019) 125:609-27
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Ortiz-Sanchez P, Villalba-Orero M, Lopez-Olaneta MM, Larrasa-Alonso J, Sanchez-Cabo F, Marti-Gomez C, Camafeita E, Gomez-Salinero JM, Ramos-Hernandez L, Nielsen PJ, Vazquez J, Muller-McNicoll M, Garcia-Pavia P, Lara-Pezzi E Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction Related mRNAs and Severe Systolic Dysfunction Circ Res (2019) 125:170-183
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Cuartero MI, de la Parra J, Pérez-Ruiz A, Bravo-Ferrer I, Durán-Laforet V, García-Culebras A, García-Segura JM, Dhaliwal J, Frankland PW, Lizasoain I, Moro MA Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice J Clin Invest (2019) 129:1536-50

Echarri A, Pavon DM, Sanchez S, Garcia-Garcia M, Calvo E, Huerta-Lopez C, Velazquez-Carreras D, Viaris de Lesegno C, Ariotti N, Lazaro-Carrillo A, Strippoli R, De Sancho D, Alegre-Cebollada J, Lamaze C, Parton RG, Del Pozo MA An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation Nat Commun (2019) 10:5828
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Pontes-Quero S, Fernandez-Chacón M, Lou W, Lunella FF, Casquero-Garcia V, Garcia-Gonzalez I, Hermoso A, Ferreira Rocha S, Bansal M, Benedito R High mitogenic stimulation arrests angiogenesis Nat Commun (2019) 10:2016
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Fernandez-Chacon M, Casquero-Garcia V, Lou W, Lunella FF, Ferreira Rocha S, Del Olmo-Cabrera S, Benedito R iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications Nat Commun (2019) 10:2262
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Hamczyk MR, Villa-Bellosta R, Quesada V, Gonzalo P, Vidak S, Nevado RM, Andrés-Manzano MJ, Misteli T, López-Otín C, Andrés V. Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells. EMBO Mol Med (2019) 11:e9736
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Wculek SK, Amores-Iniesta J, Conde-Garrosa R, Khouili SC, Melero I, Sancho D Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen J Immunother Cancer (2019) 7:100
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Herrero-Galan E, Martinez-Martin I, Alegre-Cebollada J. Redox regulation of protein nanomechanics in health and disease: lessons from titin. Redox Biol (2019) 21:101074
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Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade eLife (2019) 8:e49977
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Del Campo L*, Sanchez-Lopez A*, Salaices M, von Kleeck RA, Exposito E, Gonzalez-Gomez C, Cusso L, Guzman-Martinez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andres V. (LDC and ASL contributed equally) Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite. Aging Cell (2019) 18:e12936
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Lee P, Quintanilla JG, Alfonso-Almazan JM, Galan-Arriola C, Yan P, Sanchez-Gonzalez J, Perez-Castellano N, Perez-Villacastin J, Ibanez B, Loew LM, Filgueiras-Rama D. In-Vivo Ratiometric Optical Mapping Enables High-Resolution Cardiac Electrophysiology in Pig Models. Cardiovasc Res (2019) 115:1659-71
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Martinez-Lopez D, Camafeita E, Cedo L, Roldan-Montero R, Jorge I, Garcia-Marques F, Gomez-Serrano M, Bonzon-Kulichenko E, Blanco-Vaca F, Blanco-Colio LM, Michel JB, Escola-Gil JC, Vazquez J*, Martin-Ventura JL* (JV and JLMV are co-corresponding authors) APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm EBioMedicine (2019) 43:43-53
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Garcia-Lunar I, Pereda D, Santiago E, Solanes N, Nuche J, Ascaso M, Bobi J, Sierra F, Dantas AP, Galan C, San Antonio R, Sanchez-Quintana D, Sanchez-Gonzalez J, Barbera JA, Rigol M, Fuster V, Ibanez B, Sabate M, Garcia-Alvarez A. Effect of pulmonary artery denervation in postcapillary pulmonary hypertension: results of a randomized controlled translational study. Basic Res Cardiol (2019) 114:5
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Torroja C, Sanchez-Cabo F Digitaldlsorter: Deep-Learning on scRNA-Seq to Deconvolute Gene Expression Data Front Genet (2019) 10:978
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Alfonso-Almazan JM, Quintanilla JG, Garcia-Torrent MJ, Laguna-Castro S, Rodriguez-Bobada C, Gonzalez P, Gonzalez-Ferrer JJ, Salinas P, Canadas-Godoy V, Moreno J, Borrego-Bernabe L, Perez-Castellano N, Jalife J, Perez-Villacastin J, Filgueiras-Rama D Lesion Index Titration Using Contact-Force Technology Enables Safe and Effective Radiofrequency Lesion Creation at the Root of the Aorta and Pulmonary Artery Circ Arrhythm Electrophysiol (2019) 12:e007080
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Pimenta-Lopes C, Suay-Corredera C, Velázquez-Carreras D, Sánchez-Ortiz D, Alegre-Cebollada J. Concurrent atomic force spectroscopy. Comms Phys (2019) 2:91
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Calvo D, Filgueiras-Rama D, Jalife J. Mechanisms and Drug Development in Atrial Fibrillation. Pharmacol Rev (2018) 70:505-25

Padron-Barthe L, Villalba-Orero M, Gomez-Salinero J, Acin-Perez R, Cogliati S, Lopez-Olaneta M, Ortiz-Sanchez P, Bonzon-Kulichenko E, Vazquez J, Garcia-Pavia P, Rosenthal N, Enriquez JA, Lara-Pezzi E. Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function. J Am Coll Cardiol (2018) 71:654-67
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Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K Tet2-mediated clonal hematopoiesis accelerates experimental heart failure through an IL-1β/NLRP3 inflammasome mechanism J Am Coll Cardiol (2018) 72:875-86

Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes with a Human Antibody Detects Clinically Relevant Atherothrombosis J Am Coll Cardiol (2018) 71:321-35

Fernandez-Jimenez R, Al-Kazaz M, Jaslow R, Carvajal I, Fuster V. Children Present a Window of Opportunity for Promoting Health: JACC Review Topic of the Week. J Am Coll Cardiol (2018) 72:3310-9
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Ware JS, Amor-Salamanca A, Tayal U, Govind R, Serrano I, Salazar-Mendiguchia J, Garcia-Pinilla JM, Pascual-Figal DA, Nunez J, Guzzo-Merello G, Gonzalez-Vioque E, Bardaji A, Manito N, Lopez-Garrido MA, Padron-Barthe L, Edwards E, Whiffin N, Walsh R, Buchan RJ, Midwinter W, Wilk A, Prasad S, Pantazis A, Baski J, O'Regan DP, Alonso-Pulpon L, Cook SA, Lara-Pezzi E, Barton PJ, Garcia-Pavia P. Genetic Etiology for Alcohol-Induced Cardiac Toxicity. J Am Coll Cardiol (2018) 71:2293-302
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Zegri-Reiriz I, de Alarcon A, Munoz P, Martinez Selles M, Gonzalez-Ramallo V, Miro JM, Falces C, Gonzalez Rico C, Kortajarena Urkola X, Lepe JA, Rodriguez Alvarez R, Reguera Iglesias JM, Navas E, Dominguez F, Garcia-Pavia P, Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis infecciosa en E. Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse. J Am Coll Cardiol (2018) 71:2731-40

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Ponce-Balbuena D, Guerrero-Serna G, Valdivia CR, Caballero R, Diez-Guerra FJ, Jimenez-Vazquez EN, Ramirez RJ, Monteiro da Rocha A, Herron TJ, Campbell KF, Willis BC, Alvarado FJ, Zarzoso M, Kaur K, Perez-Hernandez M, Matamoros M, Valdivia HH, Delpon E, Jalife J. Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability. Circ Res (2018) 122:1501-16

Fuster JJ* and Walsh K* (JJF and KW are co-correspondig authors) Somatic mutations and clonal hematopoiesis: unexpected potential new drivers of age-related cardiovascular disease Circ Res (2018) 122:523-32

Clemente C, Rius C, Alonso-Herranz L, Martin-Alonso M, Pollan A, Camafeita E, Martinez F, Mota RA, Nunez V, Rodriguez C, Seiki M, Martinez-Gonzalez J, Andres V, Ricote M, Arroyo AG. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis. Nat Commun (2018) 9:910
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Giganti D, Yan K, Badilla CL, Fernandez JM, Alegre-Cebollada J. Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity. Nat Commun (2018) 9:185
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Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis JACC Cardiovasc Imaging (2018) 12:2015-2016

Casanova-Acebes M, Nicolas-Avila JA, Li JL, Garcia-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, N AG, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A. Neutrophils instruct homeostatic and pathological states in naive tissues. J Exp Med (2018) 215:2778-95
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Alvarez-Prado AF, Perez-Duran P, Perez-Garcia A, Benguria A, Torroja C, de Yebenes VG, Ramiro AR. A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets. J Exp Med (2018) 215:761-771
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Benito JM, Ortiz MC, Leon A, Sarabia LA, Ligos JM, Montoya M, Garcia M, Ruiz-Mateos E, Palacios R, Cabello A, Restrepo C, Rodriguez C, Del Romero J, Leal M, Munoz-Fernandez MA, Alcami J, Garcia F, Gorgolas M, Rallon N. Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers. BMC Med (2018) 16:30
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Walter W, Alonso-Herranz L, Trappetti V, Crespo I, Ibberson M, Cedenilla M, Karaszewska A, Núñez V, Xenarios I, Arroyo AG, Sánchez-Cabo F*, Ricote M*. (FSC and MR are co-corresponding author) Deciphering the Dynamic Transcriptional and Post-transcriptional Networks of Macrophages in the Healthy Heart and after Myocardial Injury. Cell Rep (2018) 23:622-36
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Moreno-Vicente R, Pavon DM, Martin-Padura I, Catala-Montoro M, Diez-Sanchez A, Quilez-Alvarez A, Lopez JA, Sanchez-Alvarez M, Vazquez J, Strippoli R, Del Pozo MA. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep (2018) 25:1622-35
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Saz-Leal P, Del Fresno C, Brandi P, Martinez-Cano S, Dungan OM, Chisholm JD, Kerr WG, Sancho D. Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection. Cell Rep (2018) 25:1118-26
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Bagwan N, Bonzon-Kulichenko E, Calvo E, Lechuga-Vieco AV, Michalakopoulos S, Trevisan-Herraz M, Ezkurdia I, Rodriguez JM, Magni R, Latorre-Pellicer A, Enriquez JA, Vazquez J. Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy. Cell Rep (2018) 23:3685-97
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Bentzon JF, Majesky MW. Lineage tracking of origin and fate of smooth muscle cells in atherosclerosis. Cardiovasc Res (2018) 114:492-500
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Prados B, Gomez-Apinaniz P, Papoutsi T, Luxan G, Zaffran S, Perez-Pomares JM, de la Pompa JL. Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death Dis (2018) 9:399
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Papoutsi T, Luna-Zurita L, Prados B, Zaffran S, de la Pompa JL. Bmp2 and Notch cooperate to pattern the embryonic endocardium. Development (2018) 145:163378

Dominguez F, Gonzalez-Lopez E, Padron-Barthe L, Cavero MA, Garcia-Pavia P. Role of echocardiography in the diagnosis and management of hypertrophic cardiomyopathy. Heart (2018) 104:261-73

Jimenez-Carretero D, Ligos JM, Martinez-Lopez M, Sancho D, Montoya MC. Flow Cytometry Data Preparation Guidelines for Improved Automated Phenotypic Analysis. J Immunol (2018) 200:3319-31

Garcia M, Navarrete-Munoz MA, Ligos JM, Cabello A, Restrepo C, Lopez-Bernaldo JC, de la Hera FJ, Barros C, Montoya M, Fernandez-Guerrero M, Estrada V, Gorgolas M, Benito JM, Rallon N. CD32 Expression is not Associated to HIV-DNA content in CD4 cell subsets of individuals with Different Levels of HIV Control. Sci Rep (2018) 8:15541
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Nicolas-Avila JA, Hidalgo A, Ballesteros I. Specialized functions of resident macrophages in brain and heart. J Leukoc Biol (2018) 104:743-756
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Gomez-Moreno D, Adrover JM, Hidalgo A. Neutrophils as effectors of vascular inflammation. Eur J Clin Invest (2018) 48:e12940
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MacGrogan D, Munch J, de la Pompa JL. Notch and interacting signalling pathways in cardiac development, disease, and regeneration. Nat Rev Cardiol (2018) 15:685-704
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Acin-Perez R, Lechuga-Vieco AV, Del Mar Munoz M, Nieto-Arellano R, Torroja C, Sanchez-Cabo F, Jimenez C, Gonzalez-Guerra A, Carrascoso I, Beninca C, Quiros PM, Lopez-Otin C, Castellano JM, Ruiz-Cabello J, Jimenez-Borreguero LJ, Enriquez JA. Ablation of the stress protease OMA1 protects against heart failure in mice. Sci Transl Med (2018) 10:4935

Vedanthan R, Fuster V. Prevention: Saving lives: the importance of having Resolve. Nat Rev Cardiol (2018) 15:7-8

Dzau V, Fuster V, Frazer J, Snair M. Investing in Global Health for Our Future. N Engl J Med (2017) 377:1292-6

Greenland P, Fuster V. Cardiovascular Risk Factor Control for All. JAMA (2017) 318:130-1

Fuster JJ*, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu C-L, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AAB, Cooper MA, Andres V, Hirschi KK, Martin KA, Walsh K* (JJF and KW are co-corresponding authors). Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (2017) 355:842-7
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Pontes-Quero S, Heredia L, Casquero-Garcia V, Fernandez-Chacon M, Luo W, Hermoso A, Bansal M, Garcia-Gonzalez I, Sanchez-Munoz MS, Perea JR, Galiana-Simal A, Rodriguez-Arabaolaza I, Del Olmo-Cabrera S, Rocha SF, Criado-Rodriguez LM, Giovinazzo G, Benedito R. Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis. Cell (2017) 170:800-14
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Minguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Pozo MA. Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance Nat Immunol (2017) 18:1150-9

Gonzalez-Lopez E, Gagliardi C, Dominguez F, Quarta CC, de Haro-Del Moral FJ, Milandri A, Salas C, Cinelli M, Cobo-Marcos M, Lorenzini M, Lara-Pezzi E, Foffi S, Alonso-Pulpon L, Rapezzi C, Garcia-Pavia P. Clinical characteristics of wild-type transthyretin cardiac amyloidosis: disproving myths. Eur Heart J (2017) 38:1895-1904
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Fernandez-Jimenez R, Barreiro-Perez M, Martin-Garcia A, Sanchez-Gonzalez J, Aguero J, Galan-Arriola C, Garcia-Prieto J, Diaz-Pelaez E, Vara P, Martinez I, Zamarro I, Garde B, Sanz J, Fuster V, Sanchez PL, Ibanez B. Dynamic Edematous Response of the Human Heart to Myocardial Infarction: Implications for Assessing Myocardial Area at Risk and Salvage. Circulation (2017) 1326:1288-1300
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Nicolás-Ávila JA, Adrover JM, Hidalgo A. Neutrophils in Homeostasis, Immunity, and Cancer. Immunity (2017) 46:15-28
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López-Melgar B, Fernández-Friera L, Oliva B, García-Ruiz JM, Peñalvo JL, Gómez-Talavera S, Sánchez-González J, Mendiguren JM, Ibáñez B, Fernández-Ortiz A, Sanz J, Fuster V. Subclinical Atherosclerosis Burden by 3D Ultrasound in Mid-Life: The PESA Study. J Am Coll Cardiol (2017) 70:301-13
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Uzhova I, Fuster V, Fernandez-Ortiz A, Ordovas JM, Sanz J, Fernandez-Friera L, Lopez-Melgar B, Mendiguren J, Ibanez A, Bueno H, Penalvo JL. The Importance of Breakfast in Atherosclerosis Disease: Insights From the PESA Study. J Am Coll Cardiol (2017) 70:1833-42

Fernández-Alvira JM, Fuster V, Pocock S, Sanz J, Fernández-Friera L, Laclaustra M, Fernández-Jiménez R, Mendiguren J, Fernández-Ortiz A, Ibáñez B, Bueno H. Predicting Subclinical Atherosclerosis in Low-Risk Individuals: Ideal Cardiovascular Health Score and Fuster-BEWAT Score J Am Coll Cardiol (2017) 70:2463-73
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Fuster V, Frazer J, Snair M, Vedanthan R, Dzau V, Committee on Global Health and the Future of the United States: A Report of the National Academies of Sciences, Engineering and Medicine The Future Role of the United States in Global Health: Emphasis on Cardiovascular Disease. J Am Coll Cardiol (2017) 70:3140-56

Fernandez-Friera L, Fuster V, Lopez-Melgar B, Oliva B, Garcia-Ruiz JM, Mendiguren J, Bueno H, Pocock S, Ibanez B, Fernandez-Ortiz A, Sanz J. Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors. J Am Coll Cardiol (2017) 70:2979-91
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Villalba-Orero M, Sanchez-Elexpuru G, Lopez-Olaneta M, Campuzano O, Bello-Arroyo E, Garcia-Pavia P, Serratosa JM, Brugada R, Sanchez MP, Lara-Pezzi E. Lafora Disease Is an Inherited Metabolic Cardiomyopathy. J Am Coll Cardiol (2017) 69:3007-9
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Amor-Salamanca A, Castillo S, Gonzalez-Vioque E, Dominguez F, Quintana L, Lluis-Ganella C, Escudier JM, Ortega J, Lara-Pezzi E, Alonso-Pulpon L, Garcia-Pavia P. Genetically Confirmed Familial Hypercholesterolemia in Patients With Acute Coronary Syndrome. J Am Coll Cardiol (2017) 70:1732-40
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Bartolome-Izquierdo N, De Yebenes VG, Alvarez-Prado AF, Mur SM, Lopez JA, Roa S, Vazquez J, Ramiro AR. miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma. Blood (2017) 129:2408-19
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Fernandez-Jimenez R, Galan-Arriola C, Sanchez-Gonzalez J, Aguero J, Lopez-Martin G, Gomez-Talavera S, Garcia-Prieto J, Benn A, de Molina A, Barreiro-Perez M, Martin-Garcia A, Garcia-Lunar I, Pizarro G, Sanz J, Sanchez P, Fuster V, Ibanez B. Effect of Ischemia Duration and Protective Interventions on the Temporal Dynamics of Tissue Composition After Myocardial Infarction. Circ Res (2017) 121:439-50
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Bongianino R, Denegri M, Mazzanti A, Lodola F, Vollero A, Boncompagni S, Fasciano S, Rizzo G, Mangione D, Barbaro S, Di Fonso A, Napolitano C, Auricchio A, Protasi F, Priori SG. Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2). Circ Res (2017) 121:525-36

Manteca A, Schonfelder J, Alonso-Caballero A, Fertin MJ, Barruetabena N, Faria BF, Herrero-Galan E, Alegre-Cebollada J, De Sancho D, Perez-Jimenez R. Mechanochemical evolution of the giant muscle protein titin as inferred from resurrected proteins. Nat Struct Mol Biol (2017) 24:652-7
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Garcia-Prieto J, Villena-Gutierrez R, Gomez M, Bernardo E, Pun-Garcia A, Garcia-Lunar I, Crainiciuc G, Fernandez-Jimenez R, Sreeramkumar V, Bourio-Martinez R, Garcia-Ruiz JM, Del Valle AS, Sanz-Rosa D, Pizarro G, Fernandez-Ortiz A, Hidalgo A, Fuster V, Ibanez B. Neutrophil stunning by metoprolol reduces infarct size. Nat Commun (2017) 8:14780
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Pérez-García A, Marina-Zárate E, Álvarez-Prado ÁF, Ligos JM, Galjart N, Ramiro AR. CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation. Nat Commun (2017) 8:16067

Enamorado M, Iborra S, Priego E, Cueto FJ, Quintana JA, Martínez-Cano S, Mejías-Pérez E, Esteban M, Melero I, Hidalgo A, Sancho D. Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells. Nat Commun (2017) 8:16073
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A-Gonzalez N, Quintana JA, Garcia-Silva S, Mazariegos M, Gonzalez de la Aleja A, Nicolas-Avila JA, Walter W, Adrover JM, Crainiciuc G, Kuchroo VK, Rothlin CV, Peinado H, Castrillo A, Ricote M, Hidalgo A. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med (2017) 214:1281-96
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Diaz-Diaz C, Fernandez de Manuel L, Jimenez-Carretero D, Montoya MC, Claveria C, Torres M. Pluripotency Surveillance by Myc-Driven Competitive Elimination of Differentiating Cells. Dev Cell (2017) 42:585-99
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Ivanovitch K, Temiño Valbuena s, Torres M. Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis. eLife (2017) 6:30668
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Villalba-Orero M, Lopez-Olaneta MM, Gonzalez-Lopez E, Padron-Barthe L, Gomez-Salinero JM, Garcia-Prieto J, Wai T, Garcia-Pavia P, Ibanez B, Jimenez-Borreguero LJ, Lara-Pezzi E. Lung ultrasound as a translational approach for non-invasive assessment of heart failure with reduced or preserved ejection fraction in mice. Cardiovasc Res (2017) 113:1113-23
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Padron-Barthe L, Dominguez F, Garcia-Pavia P, Lara-Pezzi E. Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics. Basic Res Cardiol (2017) 112:50
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Munch J, Grivas D, Gonzalez-Rajal A, Torregrosa-Carrion R, de la Pompa JL. Notch signalling restricts inflammation and serpine1 in the dynamic endocardium of the regenerating zebrafish heart. Development (2017) 144:1425-40

Aguado T, Gutierrez FJ, Aix E, Schneider RP, Giovinnazo G, Blasco MA, Flores I. Telomere length defines the cardiomyocyte differentiation potency of mouse induced pluripotent stem cells. Stem Cells (2017) 35:362-73

Hagensen MK, Mortensen MB, Kjolby M, Stillits NL, Steffensen LB, Bentzon JF. Type 1 diabetes increases retention of low-density lipoprotein in the atherosclerosis-prone area of the murine aorta. Atherosclerosis (2017) 263:7-14
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Garcia M, Gorgolas M, Cabello A, Estrada V, Ligos JM, Fernandez-Guerrero M, Barros C, Lopez-Bernaldo JC, De La Hera FJ, Montoya M, Benito JM, Rallon N. Peripheral T follicular helper Cells Make a Difference in HIV Reservoir Size between Elite Controllers and Patients on Successful cART. Sci Rep (2017) 7:16799
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Nehrhoff I, Ripoll J, Samaniego R, Desco M, Gómez-Gaviro MV. Looking inside the heart: a see-through view of the vascular tree. Biomed Opt Express (2017) 8:3110-8

Sánchez-Díaz R, Blanco-Dominguez R, Lasarte S, Tsilingiri K, Martín-Gayo E, Linillos-Pradillo B, de la Fuente H, Sánchez-Madrid F, Nakagawa R, Toribio ML, Martín P. Thymus-derived Treg cell development is regulated by C-type-lectin–mediated BIC/miRNA155 expression. Mol Cell Biol (2017) 37:e00341-16
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Morado M, Freire Sandes A, Colado E, Subirá D, Isusi P, Soledad Noya M, Belén Vidriales M, Sempere A, Ángel Díaz J, Minguela A, Álvarez B, Serrano C, Caballero T, Rey M, Pérez Corral A, Cristina Fernández Jiménez M, Magro E, Lemes A, Benavente C, Bañas H, Merino J, Castejon C, Gutierrez O, Rabasa P, Vescosi Gonçalves M, Perez-Andres M, Orfao A; PNH working group of the Iberian Society of Cytometry (SIC). Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications. CYTOM PART B-CLIN CY (2017) 92:361-370
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Zaldo C, Serrano MD, Han X, Cascales C, Cantero M, Montoliu L, Arza E, Caiolfa VR, Zamai M. Efficient up-conversion in Yb:Er:NaT(XO4)2 thermal nanoprobes. Imaging of their distribution in a perfused mouse. PLoS One (2017) 12:e0177596
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Jacobsen K, Lund MB, Shim J, Gunnersen S, Fuchtbauer EM, Kjolby M, Carramolino L, Bentzon JF. Diverse cellular architecture of atherosclerotic plaque derives from clonal expansion of a few medial SMCs. JCI Insight (2017) 2:95890
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Shim J, Poulsen CB, Hagensen MK, Larsen T, Heegaard PMH, Christoffersen C, Bolund L, Schmidt M, Liu Y, Li J, Li R, Callesen H, Bentzon JF, Sørensen CB. Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs. JACC Basic Transl Sci (2017) 2:591-600
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Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature (2016) 525:561-65

Cogliati S*, Calvo E*, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vazquez J*, Enriquez JA* (SC and EC contributed equally; JV and JAE are co-corresponding authors) Mechanism of super-assembly of respiratory complexes III and IV. Nature (2016) 539:579-82

Torres M. Regeneration: Limb regrowth takes two. Nature (2016) 533:328-30

Sanchez-Paulete AR, Cueto FJ, Martinez-Lopez M, Labiano S, Morales-Kastresana A, Rodriguez-Ruiz ME, Jure-Kunkel M, Azpilikueta A, Aznar MA, Quetglas JI, Sancho D*, Melero I* (DS and IM are co-senior and co-corresponding authors) Cancer immunotherapy with immunomodulatory anti-CD137 and anti-PD-1 monoclonal antibodies requires Batf3-dependent dendritic cells. Cancer Discov (2016) 6:71-9
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Cibrian D, Saiz ML, de la Fuente H, Sanchez-Diaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vazquez J, Punzon C, Fresno M, Vicente-Manzanares M, Dauden E, Fernandez-Salguero PM, Martin P, Sanchez-Madrid F. CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis. Nat Immunol (2016) 17:985-96

Garaude J*, Acín-Pérez R, Martínez-Cano S, Enamorado M, Ugolini M, Nistal-Villán E, Hervás-Stubbs S, Pelegrín P, Sander LE, Enríquez JA*, Sancho D* (JG, JAE and DS are co-corresponding authors) Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defence Nat Immunol (2016) 17:1037-45

Willis BC, Pandit S, Ponce-Balbuena D, Zarzoso M, Guerrero-Serna G, Limbu B, Deo M, Cammors E, Ramirez RJ, Mironov S, Herron TJ, Valdivia HH, Jalife J. Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress than Ventricular Myocytes from Mice with Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation (2016) 133:2348-59
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Iborra S, Martínez-López M, Khouili SC, Enamorado M, Cueto FJ, Conde-Garrosa R, del Fresno C, Sancho D Optimal generation of tissue-resident but not circulating memory T cells during viral infection requires crosspriming by DNGR-1+ dendritic cells Immunity (2016) 45:847-60

Iborra S, Martinez-Lopez M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martin Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D. Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection. Immunity (2016) 45:788-801
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Fernández-Alvira JM, Fuster V, Dorado B, Soberón N, Flores I, Gallardo M, Pocock S, Blasco MA, Andrés V. Short Telomere Load, Telomere Length, and Subclinical Atherosclerosis: The PESA Study. J Am Coll Cardiol (2016) 67:2467-76
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Gomez E*, Fernandez-Alvira JM*, Vilanova M, Haro D, Martinez R, Carvajal I, Carral V, Rodriguez C, de Miguel M, Bodega P, Santos-Beneit G, Penalvo JL, Marina I, Perez-Farinos N, DalRe M, Villar C, Robledo T, Vedanthan R, Bansilal S, Fuster V (EG and JMFA contributed equally) A Comprehensive Lifestyle Peer-Group-Based Intervention on Cardiovascular Risk Factors: The Randomized Controlled Fifty-Fifty Program. J Am Coll Cardiol (2016) 67:476-85

Laclaustra M, Casasnovas JA, Fernandez-Ortiz A, Fuster V, Leon-Latre M, Jimenez-Borreguero LJ, Pocovi M, Hurtado-Roca Y, Ordovas JM, Jarauta E, Guallar E, Ibanez B, Civeira F. Femoral and Carotid Subclinical Atherosclerosis Association With Risk Factors and Coronary Calcium: The AWHS Study. J Am Coll Cardiol (2016) 67:1263-74

Penalvo JL, Fernandez-Friera L, Lopez-Melgar B, Uzhova I, Oliva B, Fernandez-Alvira JM, Laclaustra M, Pocock S, Mocoroa A, Mendiguren JM, Sanz G, Guallar E, Bansilal S, Vedanthan R, Jimenez-Borreguero LJ, Ibanez B, Ordovas JM, Fernandez-Ortiz A, Bueno H, Fuster V. Association Between a Social-Business Eating Pattern and Early Asymptomatic Atherosclerosis. J Am Coll Cardiol (2016) 68:805-14
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Bansilal S, Castellano JM, Garrido E, Wei HG, Freeman A, Spettell C, Garcia-Alonso F, Lizano I, Arnold RJ, Rajda J, Steinberg G, Fuster V. Assessing the Impact of Medication Adherence on Long-Term Cardiovascular Outcomes. J Am Coll Cardiol (2016) 68:789-801

Arbab-Zadeh A, Fuster V. The Risk Continuum of Atherosclerosis and its Implications for Defining CHD by Coronary Angiography. J Am Coll Cardiol (2016) 68:2467-78

Bentzon JF. Targeting Inflammation in Atherosclerosis. J Am Coll Cardiol (2016) 68:2794-6

Arbab-Zadeh A, Fuster V. The Risk Continuum of Atherosclerosis and its Implications for Defining CHD by Coronary Angiography. J Am Coll Cardiol (2016) 68:2467-78

Mazzanti A, Ng K, Faragli A, Maragna R, Chiodaroli E, Orphanou N, Monteforte N, Memmi M, Gambelli P, Novelli V, Bloise R, Catalano O, Moro G, Tibollo V, Morini M, Bellazzi R, Napolitano C, Bagnardi V, Priori SG. Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Course and Predictors of Arrhythmic Risk. J Am Coll Cardiol (2016) 68:2540-50

Mazzanti A, Maragna R, Faragli A, Monteforte N, Bloise R, Memmi M, Novelli V, Baiardi P, Bagnardi V, Etheridge SP, Napolitano C, Priori SG. Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3. J Am Coll Cardiol (2016) 67:1053-8

Gallego-Delgado M, Delgado JF, Brossa-Loidi V, Palomo J, Marzoa-Rivas R, Perez-Villa F, Salazar-Mendiguchía J, Ruiz-Cano MJ, Gonzalez-Lopez E, Padron-Barthe L, Bornstein B, Alonso-Pulpon L, Garcia-Pavia P Idiopathic restrictive cardiomyopathy is primarily a genetic disease J Am Coll Cardiol (2016) 67:3021-3023
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Calvo E, Garcia-Alvarez A, Vazquez J. The Quest for Metabolic Biomarkers of Pulmonary Hypertension. J Am Coll Cardiol (2016) 67:190-2

Enriquez JA. Supramolecular Organization of Respiratory Complexes. Annu Rev Physiol (2016) 78:533-61

D'Amato G, Luxan G, Del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL. Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol (2016) 18:7-20

de Luxan G, D'Amato G, MacGrogan D, de la Pompa JL. Endocardial Notch Signaling in Cardiac Development and Disease. Circ Res (2016) 118:e1-18

MacGrogan D, D'Amato G, Travisano S, Martinez-Poveda B, de Luxan G, Del Monte-Nieto G, Papoutsi T, Sbroggio M, Bou V, Gomez-Del Arco P, Gomez MJ, Zhou B, Redondo JM, Jimenez-Borreguero LJ, de la Pompa JL. Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis. Circ Res (2016) 118:1480-97

Fuster V, Ibanez B, Andres V. The CNIC: A Successful Vision in Cardiovascular Research. Circ Res (2016) 119:758-9
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de Luxan G, D'Amato G, MacGrogan D, de la Pompa JL. Endocardial Notch Signaling in Cardiac Development and Disease. Circ Res (2016) 118:e1-18

Fuster JJ*, Ouchi N, Gokce N, Walsh K* (JJF and KW are co-corresponding authors) Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease Circ Res (2016) 118:1786-807

Leiva M, Quintana JA, Ligos JM, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFbeta availability. Nat Commun (2016) 7:10222
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Gonzalez-Teran B, Lopez JA, Rodriguez E, Leiva L, Martinez-Martinez S, Bernal JA, Jimenez-Borreguero LJ, Redondo JM, Vazquez J, Sabio G. p38gamma and delta promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. Nat Commun (2016) 7:10477
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Perez-Medina C, Abdel-Atti D, Tang J, Zhao Y, Fayad ZA, Lewis JS, Mulder WJ, Reiner T. Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nat Commun (2016) 7:11838
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Zhao Y, Fay F, Hak S, Manuel Perez-Aguilar J, Sanchez-Gaytan BL, Goode B, Duivenvoorden R, de Lange Davies C, Bjørkøy A, Weinstein H, Fayad ZA, Pérez-Medina C, Mulder WJ Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy Nat Commun (2016) 7:11221

Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ. In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models. JACC Cardiovasc Imaging (2016) 9:950-61

Rivera-Torres J, Calvo CJ, Llach A, Guzman-Martinez G, Caballero R, Gonzalez-Gomez C, Jimenez-Borreguero LJ, Guadix JA, Osorio FG, Lopez-Otin C, Herraiz-Martinez A, Cabello N, Vallmitjana A, Benitez R, Gordon LB, Jalife J, Perez-Pomares JM, Tamargo J, Delpon E, Hove-Madsen L, Filgueiras-Rama D, Andres V. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A (2016) 113:E7250–9
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Cuenca S, Ruiz-Cano MJ, Gimeno-Blanes JR, Jurado A, Salas C, Gomez-Diaz I, Padron-Barthe L, Grillo JJ, Vilches C, Segovia J, Pascual-Figal D, Lara-Pezzi E, Monserrat L, Alonso-Pulpon L, Garcia-Pavia P, Inherited Cardiac Diseases Program of the Spanish Cardiovascular Research N. Genetic basis of familial dilated cardiomyopathy patients undergoing heart transplantation. J Heart Lung Transplant (2016) 35:625-35

Nus M*, Martinez-Poveda B*, MacGrogan D*, Chevre R, D'Amato G, Sbroggio M, Rodriguez C, Martinez-Gonzalez J, Andres V, Hidalgo A, de la Pompa JL. (MN, BMP and DM contributed equally) Endothelial Jag1-RBPJ signalling promotes inflammatory leukocyte recruitment and atherosclerosis. Cardiovasc Res (2016) 112:568-80

Garcia-Alvarez A, Pereda D, Garcia-Lunar I, Sanz-Rosa D, Fernandez-Jimenez R, Garcia-Prieto J, Nuno-Ayala M, Sierra F, Santiago E, Sandoval E, Campelos P, Aguero J, Pizarro G, Peinado VI, Fernandez-Friera L, Garcia-Ruiz JM, Barbera JA, Castella M, Sabate M, Fuster V, Ibanez B. Beta-3 adrenergic agonists reduce pulmonary vascular resistance and improve right ventricular performance in a porcine model of chronic pulmonary hypertension. Basic Res Cardiol (2016) 111:49
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Lodola F, Morone D, Denegri M, Bongianino R, Nakahama H, Rutigliano L, Gosetti R, Rizzo G, Vollero A, Buonocore M, Napolitano C, Condorelli G, Priori SG, Di Pasquale E. Adeno-associated virus-mediated CASQ2 delivery rescues phenotypic alterations in a patient-specific model of recessive catecholaminergic polymorphic ventricular tachycardia. Cell Death Dis (2016) 7:e2393

Shim J, Al-Mashhadi RH, Sorensen CB, Bentzon JF. Large animal models of atherosclerosis - new tools for persistent problems in cardiovascular medicine. J Pathol (2016) 238:257-66

Pereda D, Garcia-Lunar I, Sierra F, Sanchez-Quintana D, Santiago E, Ballesteros C, Encalada JF, Sanchez-Gonzalez J, Fuster V, Ibanez B, Garcia-Alvarez A. Magnetic Resonance Characterization of Cardiac Adaptation and Myocardial Fibrosis in Pulmonary Hypertension Secondary to Systemic-To-Pulmonary Shunt. Circ Cardiovasc Imaging (2016) 9:e004566
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Garcia-Quintans N, Sanchez-Ramos C, Prieto I, Tierrez A, Arza E, Alfranca A, Redondo JM, Monsalve M. Oxidative stress induces loss of pericyte coverage and vascular instability in PGC-1alpha-deficient mice. Angiogenesis (2016) 19:217-28

Lillo-Castellano JM, Marina-Breysse M, Gomez-Gallanti A, Martinez-Ferrer JB, Alzueta J, Perez-Alvarez L, Alberola A, Fernandez-Lozano I, Rodriguez A, Porro R, Anguera I, Fontenla A, Gonzalez-Ferrer JJ, Canadas-Godoy V, Perez-Castellano N, Garofalo D, Salvador-Montanes O, Calvo CJ, Quintanilla JG, Peinado R, Mora-Jimenez I, Perez-Villacastin J, Rojo-Alvarez JL, Filgueiras-Rama D. Safety threshold of R-wave amplitudes in patients with implantable cardioverter defibrillator. Heart (2016) 102:1662-70

Rallon NI, Mothe B, Lopez Bernaldo DEQJC, Plana M, Ligos JM, Montoya M, Munoz MA, Esteban M, Garcia F, Brander C, Benito JM, Group RS. Balance between activation and regulation of HIV-specific CD8 T cells response after MVA-B therapeutic vaccination. AIDS (2016) 30:553-62

Sala-Vila A*, Navarro-Lerida I*, Sanchez-Alvarez M, Bosch M, Calvo C, Lopez JA, Calvo E, Ferguson C, Giacomello M, Serafini A, Scorrano L, Enriquez JA, Balsinde J, Parton RG, Vazquez J, Pol A, Del Pozo MA. (*ASV and INL contributed equally) Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice. Sci Rep (2016) 6:27351
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Cordoba R, Alvarez B, Masso P, Gonzalez FA, Conejo L, Velasco D, Alonso JM, Villarrubia J, Cava F, Llamas P. The utility of multiparametric seven-color flow cytometry in the detection of double hit lymphoma in ascitic fluid samples. CYTOM PART B-CLIN CY (2016) 90:543-545
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Wai T, García-Prieto J, Baker MJ, Merkwirth C, Benit P, Rustin P, Rupérez FJ, Barbas C, Ibanez B*, Langer T*. (BI and TL are co-corresponding authors) Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science (2015) 350:aad0116

Fernandez-Friera L, Penalvo JL, Fernandez-Ortiz A, Ibanez B, Lopez-Melgar B, Laclaustra M, Oliva B, Mocoroa A, Mendiguren J, Martinez de Vega V, Garcia L, Molina J, Sanchez-Gonzalez J, Guzman G, Alonso-Farto JC, Guallar E, Civeira F, Sillesen H, Pocock S, Ordovas JM, Sanz G, Jimenez-Borreguero LJ, Fuster V Prevalence, Vascular Distribution and Multi-territorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort: The PESA (Progression of Early Subclinical Atherosclerosis) Study. Circulation (2015) 131:2104-13
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Priori SG, Blomstrom-Lundqvist C, Mazzanti A, Blom N, Borggrefe M, Camm J, Elliott PM, Fitzsimons D, Hatala R, Hindricks G, Kirchhof P, Kjeldsen K, Kuck KH, Hernandez-Madrid A, Nikolaou N, Norekval TM, Spaulding C, Van Veldhuisen DJ. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J (2015) 36:2793-867

Cruz FM, Sanz-Rosa D, Roche-Molina M, Garcia-Prieto J, Garcia-Ruiz JM, Pizarro G, Jimenez-Borreguero LJ, Torres M, Bernad A, Ruiz-Cabello J, Fuster V, Ibanez B and Bernal JA. Exercise Triggers ARVC Phenotype in Mice Expressing a Disease-Causing Mutated Version of Human Plakophilin-2 J Am Coll Cardiol (2015) 65:1438-50

Penalvo JL, Santos-Beneit G, Sotos-Prieto M, Bodega P, Oliva B, Orrit X, Rodriguez C, Fernandez-Alvira JM, Redondo J, Vedanthan R, Bansilal S, Gomez E, Fuster V. The SI! Program for Cardiovascular Health Promotion in Early Childhood: A Cluster-Randomized Trial. J Am Coll Cardiol (2015) 66:1525-34

Fernandez-Jimenez R, Sanchez-Gonzalez J, Aguero J, Garcia-Prieto J, Lopez-Martin GJ, Garcia-Ruiz JM, Molina-Iracheta A, Rossello X, Fernandez-Friera L, Pizarro G, Garcia-Alvarez A, Dall'Armellina E, Macaya C, Choudhury RP, Fuster V, Ibanez B Myocardial Edema After Ischemia/Reperfusion Is Not Stable and Follows a Bimodal Pattern: Advanced Imaging and Histological Tissue Characterization J Am Coll Cardiol (2015) 65:315-23
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Navarro-Lérida I, Pellinen T, Sánchez SA, Guadamillas MC, Wang Y, Mirtti T, Calvo, Del Pozo MA. Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion Dev Cell (2015) 32:318-334

Park DS, Cerrone M, Morley G, Vasquez C, Fowler S, Liu N, Bernstein SA, Liu FY, Zhang J, Rogers CS, Priori SG, Chinitz LA, Fishman GI. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. J Clin Invest (2015) 125:403-12

Strippoli R, Loureiro J, Moreno V, Benedicto I, Perez Lozano ML, Barreiro O, Pellinen T, Minguet S, Foronda M, Osteso MT, Calvo E, Vazquez J, Lopez Cabrera M, Del Pozo MA Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis EMBO Mol Med (2015) 7:102-23
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Perez-Garcia A, Perez-Duran P, Wossning T, Sernandez IV, Mur SM, Canamero M, Real FX, Ramiro AR. AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway. EMBO Mol Med (2015) 7:1327-36
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Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K Non-canonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction Diabetes (2015) 64:1235-48

Bednarek D, Gonzalez-Rosa JM, Guzman-Martinez G, Gutierrez-Gutierrez O, Aguado T, Sanchez-Ferrer C, Marques IJ, Galardi-Castilla M, de Diego I, Gomez MJ, Cortes A, Zapata A, Jimenez-Borreguero LJ, Mercader N*, Flores I*. (NM and IF are co-corresponding authors) Telomerase Is Essential for Zebrafish Heart Regeneration. Cell Rep (2015) 12:1691-703
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Bersini S, Gilardi M, Arrigoni C, Talo G, Zamai M, Zagra L, Caiolfa V, Moretti M. Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach. Biomaterials (2015) 76:157-72

Roche-Molina M, Sanz-Rosa D, Cruz FM, Garcia-Prieto J, Lopez S, Abia R, Muriana FJ, Fuster V, Ibanez B, Bernal JA Induction of Sustained Hypercholesterolemia by Single Adeno-Associated Virus-Mediated Gene Transfer of Mutant hPCSK9 Arterioscler Thromb Vasc Biol (2015) 35:50-9

Steffensen LB, Mortensen MB, Kjolby M, Hagensen MK, Oxvig C, Bentzon JF. Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery Wall: A Key Mechanism Distinguishing Susceptible From Resistant Sites. Arterioscler Thromb Vasc Biol (2015) 35:1928-35

Garcia-Alvarez A, Garcia-Lunar I, Pereda D, Fernandez-Jimenez R, Sanchez-Gonzalez J, Mirelis JG, Nuno-Ayala M, Sanchez-Quintana D, Fernandez-Friera L, Garcia-Ruiz JM, Pizarro G, Aguero J, Campelos P, Castella M, Sabate M, Fuster V, Sanz J, Ibanez B Association of Myocardial T1-Mapping CMR With Hemodynamics and RV Performance in Pulmonary Hypertension JACC Cardiovasc Imaging (2015) 8:76-82

Cruz FM, Tome M, Bernal JA, Bernad A. miR-300 mediates Bmi1 function and regulates differentiation in primitive cardiac progenitors. Cell Death Dis (2015) 6:e1953
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Perez-Medina C, Tang J, Abdel-Atti D, Hogstad B, Merad M, Fisher EA, Fayad ZA, Lewis JS, Mulder WJ, Reiner T. PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles. J Nucl Med (2015) 56:1272-7

Filgueiras-Rama D, Calvo CJ, Salvador-Montanes O, Cadenas R, Ruiz-Cantador J, Armada E, Rey JR, Merino JL, Peinado R, Perez-Castellano N, Perez-Villacastin J, Quintanilla JG, Jimenez S, Castells F, Chorro FJ, Lopez-Sendon JL, Berenfeld O, Jalife J, de Sa EL, Millet J Spectral analysis-based risk score enables early prediction of mortality and cerebral performance in patients undergoing therapeutic hypothermia for ventricular fibrillation and comatose status Int J Cardiol (2015) 186:250-8

Walter W, Sanchez-Cabo F*, Ricote M* (*equal contribution) GOplot: an R package for visually combining expression data with functional analysis. Bioinformatics (2015) 31:2912-4
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Bongianino R, Priori SG. Gene therapy to treat cardiac arrhythmias. Nat Rev Cardiol (2015) 12:531-46

Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding Cell (2014) 156:1234-46

Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi M-D, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A Neutrophils scan for activated platelets to initiate inflammation Science (2014) 346:1234-8

Martins RP, Kaur K, Hwang E, Ramirez RJ, Willis BC, Filgueiras-Rama D, Ennis SR, Takemoto Y, Ponce-Balbuena D, Zarzoso M, O'Connell RP, Musa H, Guerrero-Serna G, Avula UM, Swartz MF, Bhushal S, Deo M, Pandit SV, Berenfeld O, Jalife J. Dominant Frequency Increase Rate Predicts Transition from Paroxysmal to Long-Term Persistent Atrial Fibrillation. Circulation (2014) 129:1472-82

Denegri M, Bongianino R, Lodola F, Boncompagni S, De Giusti VC, Avelino-Cruz JE, Liu N, Persampieri S, Curcio A, Esposito F, Pietrangelo L, Marty I, Villani L, Moyaho A, Baiardi P, Auricchio A, Protasi F, Napolitano C, Priori SG. Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age. Circulation (2014) 129:2673-81

Cuartero MI, Ballesteros I, Parra J, Harkin AL, Abautret-Daly A, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA Deleterious role of the aryl hydrocarbon receptor and its agonist l-kynurenin in acute ischemic brain damage Circulation (2014) 130:2040-51

Acín-Pérez R, Carrascoso I, Baixauli F, Roche-Molina M, Latorre-Pellicer A, Fernández-Silva P, Mittelbrunn M, Sánchez-Madrid F, Pérez-Martos A, Lowell CA, Manfredi G and Enríquez JA ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use. Cell Metab (2014) 19:1020-33

Castellano JM, Sanz G, Penalvo JL, Bansilal S, Fernandez-Ortiz A, Alvarez L, Guzman L, Linares JC, Garcia F, D'Aniello F, Arnaiz JA, Varea S, Martinez F, Lorenzatti A, Imaz I, Sanchez-Gomez LM, Roncaglioni MC, Baviera M, Smith SC, Jr., Taubert K, Pocock S, Brotons C, Farkouh ME, Fuster V A polypill strategy to improve adherence: results from FOCUS (Fixed-dose Combination Drug for Secondary Cardiovascular Prevention) Project J Am Coll Cardiol (2014) 64:2071-82

Mortensen MB, Kjolby M, Gunnersen S, Larsen JV, Palmfeldt J, Falk E, Nykjaer A, Bentzon JF Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis J Clin Invest (2014) 124:5317-22

Chèvre R, González-Granado JM, Megens RT, Sreeramkumar V, Silvestre-Roig C, Molina-Sanchez P, Weber C, Soehnlein O, Hidalgo A*, Andrés V* (VA and AH contributed equally). High-Resolution Imaging of Intravascular Atherogenic Inflammation in Live Mice. Circ Res (2014) 114:770-9
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Bentzon JF, Otsuka F, Virmani R, Falk E Mechanisms of plaque formation and rupture Circ Res (2014) 114:1852-66

Bjørklund MM, Hollensen AK, Hagensen MK, Dagnaes-Hansen F, Christoffersen C, Mikkelsen JG, Bentzon JF Induction of atherosclerosis in mice and hamsters without germline genetic engineering Circ Res (2014) 114:1684-9

Bentzon JF, Otsuka F, Virmani R, Falk E Mechanisms of plaque formation and rupture Circ Res (2014) 114:1852-66

de Yebenes VG, Bartolome-Izquierdo N, Nogales-Cadenas R, Perez-Duran P, Mur SM, Martinez N, Di Lisio L, Robbiani DF, Pascual-Montano A, Canamero M, Piris MA and Ramiro AR. miR-217 is an oncogene that enhances the germinal center reaction. Blood (2014) 124:229-39

Hermann M, Stillhard P, Wildner H, Seruggia D, Kapp V, Sánchez-Iranzo H, Mercader N, Montoliu L, Zeilhofer HU, Pelczar P Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Res (2014) 42:3894-807

Cortes JR*, Sanchez-Diaz R*, Bovolenta ER, Barreiro O, Lasarte S, Matesanz-Marin A, Toribio ML, Sanchez-Madrid F, Martin P (JRC and RSD contributed equally) Maintenance of immune tolerance by Foxp3+ regulatory T cells requires CD69 expresion J Autoimmun (2014) 55C:51-62

Rosello-Diez A, Arques CG, Delgado I, Giovinazzo G and Torres M. Diffusible signals and epigenetic timing cooperate in late proximo-distal limb patterning. Development (2014) 141:1534-43

Bujak R, García-Álvarez A, Rupérez FJ, Nuño-Ayala M, García A, Ruiz-Cabello J, Fuster V, Ibáñez B, Barbas C. Metabolomics Reveals Metabolite Changes in Acute Pulmonary Embolism. J Proteome Res (2014) 13:805-16

Gonzalez-Lazaro M, Rosello-Diez A, Delgado I, Carramolino L, Sanguino MA, Giovinazzo G, Torres M. Two new Targeted alleles for the comprehensive analysis of Meis1 functions in the mouse Genesis (2014) 52:967-75

Callejas S*, Alvarez R*, Benguria A, Dopazo A (SC and RA contributed equally) AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms. Biotechniques (2014) 56:28-35

Peralta M*, González-Rosa JM*, Marques IJ, Mercader N (MP and JMGR contributed equally) The Epicardium in the Embryonic and Adult Zebrafish J Dev Biol (2014) 2:101-16
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Clavería C, Giovinazzo G, Sierra R, Torres M. Myc-driven endogenous cell competition in the early mammalian embryo. Nature (2013) 500:39-44

Parton RG, Del Pozo MA. Caveolae as plasma membrane sensors, protectors and organizers. Nat Rev Mol Cell Biol (2013) 14:98-112

Casanova-Acebes M, Pitaval C, Weiss LA, Nombela-Arrieta C, Chèvre R, A-González N, Kunisaki Y, Zhang D, van Rooijen N, Silberstein LE, Weber C, Nagasawa T, Frenette PS, Castrillo A, Hidalgo A. Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance. Cell (2013) 153:1025-1035

Lapuente-Brun E, Moreno-Loshuertos R, Acin-Perez R, Latorre-Pellicer A, Colas C, Balsa E, Perales-Clemente E, Quiros PM, Calvo E, Rodriguez-Hernandez MA, Navas P, Cruz R, Carracedo A, Lopez-Otin C, Perez-Martos A, Fernandez-Silva P, Fernandez-Vizarra E, Enriquez JA Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain Science (2013) 340:1567-70

Luxán G, Casanova JC*, Martínez-Poveda B*, Prados B, D'Amato G, Macgrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-García JL, Fernández-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibañez B, Medrano C, García-Pavía P, Gimeno JR, Monserrat L, Jiménez-Borreguero LJ, de la Pompa JL (JCC and BMP contributed equally) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med (2013) 19:193-201

Villa-Bellosta R, Rivera J, Osorio FG, Acín-Pérez R, Enríquez JA, López-Otín C, Andrés V. Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome that is Ameliorated upon Pyrophosphate Treatment. Circulation (2013) 127:2442-51
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Ibanez B*, Macaya C, Sánchez-Brunete V, Pizarro G, Fernández-Friera L, Mateos A, Fernández-Ortiz A, García-Ruiz JM, García-Alvarez A, Iñiguez A, Jiménez-Borreguero J, López-Romero P, Fernández-Jiménez R, Goicolea J, Ruiz-Mateos B, Bastante T, Arias M, Iglesias-Vázquez JA, Rodriguez MD, Escalera N, Acebal C, Cabrera JA, Valenciano J, Pérez de Prado A, Férnandez-Campos MJ, Casado I, García-Rubira JC, García-Prieto J, Sanz-Rosa D, Cuellas C, Hernández-Antolín R, Albarrán A, Fernández-Vázquez F, de la Torre-Hernández JM, Pocock SJ, Sanz G, Fuster V. (BI corresponding author) Effect of Early Metoprolol on Infarct Size in ST-Segment Elevation Myocardial Infarction Patients Undergoing Primary PCI: The METOCARD-CNIC Trial. Circulation (2013) 128:1495-1503

García-Álvarez A, Fernández-Friera L, García-Ruiz JM, Nuño-Ayala M, Pereda D, Fernández-Jiménez R, Guzmán G, Sanchez-Quintana D, Alberich-Bayarri A, Pastor-Escuredo D, Sanz-Rosa D, García-Prieto J, Mirelis JG, Pizarro G, Jimenez-Borreguero LJ, Fuster V, Sanz J, Ibáñez B. Noninvasive Monitoring of Serial Changes in Pulmonary Vascular Resistance and Acute Vasodilator Testing using Cardiac Magnetic Resonance. J Am Coll Cardiol (2013) 62:1621-31

Priori SG, Napolitano C, Di Pasquale E, Condorelli G. Induced pluripotent stem cell-derived cardiomyocytes in studies of inherited arrhythmias. J Clin Invest (2013) 123:84-91

de Yébenes VG, Bartolomé-Izquierdo N, Ramiro AR. Regulation of B-cell development and function by microRNAs. Immunol Rev (2013) 253:25-39

Pandit SV, Jalife J. Rotors and the dynamics of cardiac fibrillation. Circ Res (2013) 112:849-62

Liu N, Denegri M, Dun W, Boncompagni S, Lodola F, Protasi F, Napolitano C, Boyden PA, Priori SG. Abnormal propagation of calcium waves and ultrastructural remodeling in recessive catecholaminergic polymorphic ventricular tachycardia. Circ Res (2013) 113:142-52

Deo M, Ruan Y, Pandit SV, Shah K, Berenfeld O, Blaufox A, Cerrone M, Noujaim SF, Denegri M, Jalife J, Priori SG. KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia. Proc Natl Acad Sci U S A (2013) 110:4291-6

González-Amaro R, Cortés JR, Sánchez-Madrid F, Martín P. Is CD69 an effective brake to control inflammatory diseases? Trends Mol Med (2013) 19:625-32

Peralta M, Steed E, Harlepp S, González-Rosa JM, Monduc F, Ariza-Cosano A, Cortés A, Rayón T, Gómez-Skarmeta JL, Zapata A, Vermot J, Mercader N. Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis. Curr Biol (2013) 23:1726-35

Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G, Priori SG. CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia. Cell Death Dis (2013) 4:e843

González-Navarro H, Vinué A, Sanz MJ, Delgado M, Pozo MA, Serrano M, Burks DJ, Andrés V. Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging Aging Cell (2013) 12:102-11
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Rocha-Perugini V, Zamai M, González-Granado J, Barreiro O, Tejera E, Yañez-Mó M, Caiolfa V, Sanchez-Madrid F. CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 33:3644-58

Priori SG, Wilde AA, Horie M, Cho Y, Behr ER, Berul C, Blom N, Brugada J, Chiang CE, Huikuri H, Kannankeril P, Krahn A, Leenhardt A, Moss A, Schwartz PJ, Shimizu W, Tomaselli G, Tracy C. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm (2013) 10:1932-63

Espín R, Roca FJ, Candel S, Sepulcre MP, González-Rosa JM, Alcaraz-Pérez F, Meseguer J, Cayuela ML, Mercader N, Mulero V. TNF receptors regulate vascular homeostasis through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. Dis Model Mech (2013) 6:383-95
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Bernal JA. RNA-Based Tools for Nuclear Reprogramming and Lineage-Conversion: Towards Clinical Applications J Cardiovasc Transl Res (2013) 6:956-68
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Cavodeassi F, Bene FD, Fürthauer M, Grabher C, Herzog W, Lehtonen S, Linker C, Mercader N, Mikut R, Norton W, Strähle U, Tiso N, Foulkes NS. Report of the Second European Zebrafish Principal Investigator Meeting in Karlsruhe, Germany, March 21-24, 2012. Zebrafish (2013) 10:119-23

Al-Mashhadi RH, Sørensen CB, Kragh PM, Christoffersen C, Mortensen MB, Tolbod LP, Thim T, Du Y, Li J, Liu Y, Moldt B, Schmidt M, Vajta G, Larsen T, Purup S, Bolund L, Nielsen LB, Callesen H, Falk E, Mikkelsen JG, Bentzon JF Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant Sci Transl Med (2013) 5:166ral

Farkouh ME, Domanski M, Sleeper LA, Siami FS, Dangas G, Mack M, Yang M, Cohen DJ, Rosenberg Y, Solomon SD, Desai AS, Gersh BJ, Magnuson EA, Lansky A, Boineau R, Weinberger J, Ramanathan K, Sousa JE, Rankin J, Bhargava B, Buse J, Hueb W, Smith CR, Muratov V, Bansilal S, King S 3rd, Bertrand M, Fuster V; the FREEDOM Trial Investigators. Strategies for Multivessel Revascularization in Patients with Diabetes. N Engl J Med (2012) 367:2375-84

Benedito R, Rocha SF, Woeste M, Zamykal M, Radtke F, Casanovas O, Duarte A, Pytowski B, Adams RH. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling Nature (2012) 484:110-4

Kosuri P, Alegre-Cebollada J, Feng J, Kaplan A, Inglés-Prieto A, Badilla CL, Stockwell BR, Sanchez-Ruiz JM, Holmgren A, Fernández JM Protein folding drives disulfide formation Cell (2012) 151:794-806

Kovacic JC, Mercader N, Torres M, Boehm M, Fuster V. Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition: From Cardiovascular Development to Disease. Circulation (2012) 125:1795-808

Fuster V, Bhatt DL, Califf RM, Michelson AD, Sabatine MS, Angiolillo DJ, Bates ER, Cohen DJ, Coller BS, Furie B, Hulot JS, Mann KG, Mega JL, Musunuru K, O'Donnell CJ, Price MJ, Schneider DJ, Simon DI, Weitz JI, Williams MS, Hoots WK, Rosenberg YD, Hasan AA. Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. Circulation (2012) 126:1645-62

Kovacic JC, Mercader N, Torres M, Boehm M, Fuster V. Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition: From Cardiovascular Development to Disease. Circulation (2012) 125:1795-808

Pérez-Durán P, Belver L, de Yébenes VG, Delgado P, Pisano DG, Ramiro AR. UNG shapes the specificity of AID-induced somatic hypermutation. J Exp Med (2012) 209:1379-89

Herron TJ, Lee P, Jalife J. Optical imaging of voltage and calcium in cardiac cells & tissues. Circ Res (2012) 110:609-23

Navarro-Lérida I, Sánchez-Perales S, Calvo M, Rentero C, Zheng Y, Enrich C, Del Pozo MA. A palmitoylation switch mechanism regulates Rac1 function and membrane organization. EMBO J (2012) 31:534-51

Milstein ML, Musa H, Balbuena DP, Anumonwo JM, Auerbach DS, Furspan PB, Hou L, Hu B, Schumacher SM, Vaidyanathan R, Martens JR, Jalife J. Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia. Proc Natl Acad Sci U S A (2012) 109:2134-43

González-Rosa JM, Mercader N. Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish. Nat Protocol (2012) 7:782-8

Neto A, Mercader N, Gómez-Skarmeta JL The osr1 and osr2 genes act in the pronephric anlage downstream of retinoic acid signaling and upstream of wnt2b to maintain pectoral fin development Development (2012) 139:301-11

Echarri A, Muriel O, Pavón DM, Azegrouz H, Escolar F, Terrón MC, Sanchez-Cabo F, Martínez F, Montoya MC, Llorca O, Del Pozo MA. Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1 J Cell Sci (2012) 125:3097-113

González-Rosa JM, Peralta M, Mercader N. Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration. Dev Biol (2012) 370:173-86

Goetz JG*, Minguet S*, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA (JGG and SM contributed equally) Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis Cell (2011) 146:148-63

Alegre-Cebollada J, Kosuri P, Rivas-Pardo JA, Fernández JM. Direct observation of disulfide isomerization in a single protein. Nat Chem (2011) 3:882-7

García-Alvarez A, Fernández-Friera L, Mirelis JG, Sawit S, Nair A, Kallman J, Fuster V, Sanz J. Non-invasive estimation of pulmonary vascular resistance with cardiac magnetic resonance. Eur Heart J (2011) 32:1438-45

Bernal JA, Venkitaraman AR A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission J Cell Biol (2011) 192:969-78

Belver L, Papavasiliou FN, Ramiro AR. MicroRNA control of lymphocyte differentiation and function. Curr Opin Immunol (2011) 23:369-73

Martín P, Sánchez-Madrid F. CD69: An Unexpected Regulator of TH17 Cell-Driven Inflammatory Responses. Science Signaling (2011) 4:pe14

González-Rosa JM, Martín V, Peralta M, Torres M, Mercader N. Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish. Development (2011) 138:1663-74

Fuster JJ, González-Navarro H, Vinué A, Molina P, Andrés-Manzano MJ, Nakayama KI, Nakayama K, Díez-Juan A, Bernad A, Rodríguez C, Martínez-González J, Andrés V. Deficient p27 Phosphorylation at Serine 10 Increases Macrophage Foam Cell Formation and Aggravates Atherosclerosis Through a Proliferation-Independent Mechanism. Arterioscler Thromb Vasc Biol (2011) 31:2455-2463
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Hellriegel C*, Caiolfa VR*, Corti V, Sidenius N, Zamai M (CH and VRC contributed equally) Number and brightness image analysis reveals ATF-induced dimerization kinetics of uPAR in the cell membrane. FASEB J (2011) 25:2883-97

Belver L, de Yébenes VG, Ramiro AR. MicroRNAs prevent the generation of autoreactive antibodies. Immunity (2010) 33:713-22

Cruz-Adalia A, Jiménez-Borreguero LJ, Ramírez-Huesca M, Chico-Calero I, Barreiro O, López-Conesa E, Fresno M, Sánchez-Madrid F, Martín P. CD69 Limits the Severity of Cardiomyopathy After Autoimmune Myocarditis. Circulation (2010) 122:1396-404

González-Navarro H, Abu Nabah Y, Vinué A, Andrés-Manzano MJ, Collado M, Serrano M, Andrés V. p19(ARF) Deficiency Reduces Macrophage and Vascular Smooth Muscle Cell Apoptosis and Aggravates Atherosclerosis. J Am Coll Cardiol (2010) 55:2258-68

Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, Muzio M, Caiolfa V, Kitamura D, Restuccia U, Bachi A, Rocchi M, Ponzoni M, Ghia P, Caligaris-Cappio F. HS1 has a central role in the trafficking and homing of leukemic B cells. Blood (2010) 116:3537-46

Hellriegel C, Caiolfa VR, Sidenius N, Gratton E, Zamai M Receptor-Ligand Interactions in the Plasma Membrane of Live Cells Resolved in Space and Time by N&B Analysis Biophys J (2010) 98:750

González-Rosa JM, Padrón-Barthe L, Torres M, Mercader N. [Lineage tracing of epicardial cells during development and regeneration] Rev Esp Cardiol (2010) 63:36-48

Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis Cell (2009) 137:1124-35

Andres V, Gonzalez JM. Role of A-type lamins in signaling, transcription, and chromatin organization J Cell Biol (2009) 187:945-57

Poynter S, Phipps JD, Naranjo-Pino A, Sanchez-Morgado JM. Difficulties in the molecular diagnosis of Helicobacter rodent infections. Vet Microbiol (2009) 134:272-8

Kent ML, Feist SW, Harper C, Hoogstraten-Miller S, Law JM, Sanchez-Morgado JM, Tanguay RL, Sanders GE, Spitsbergen JM, Whipps CM. Recommendations for control of pathogens and infectious diseases in fish research facilities. Comp Biochem Physiol C Toxicol Pharmacol (2009) 149:240-8

Mercader N, Selleri L, Criado LM, Pallares P, Parras C, Cleary ML, Torres M. Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner Int J Dev Biol (2009) 53:1483-94

Sanchez-Morgado JM, Gallagher A. Johnson L Mycobacterium gordonae infection in a colony of African clawed frogs (Xenopus tropicalis). Lab Anim (2009) 43:300-3

Gonzalez-Rosa JM, Mercader N. The epicardium: development, differentiation and its role during heart regeneration Nat Rev Cardiol (CNIC Edition) (2009) 6:67-72

de Yebenes VG, Belver L, Pisano DG, Gonzalez S, Villasante A, Croce C, He L, Ramiro AR. miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J Exp Med (2008) 205:2199-206

Morales JR, Ballesteros I, Deniz JM, Hurtado O, Vivancos J, Nombela F, Lizasoain I, Castrillo A, Moro MA Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke Circulation (2008) 118:1450-9

González JM, Navarro-Puche A, Casar B, Crespo P, Andrés V. Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope. J Cell Biol (2008) 183:653-66

Digman MA, Caiolfa VR, Zamai M, Gratton E. The phasor approach to fluorescence lifetime imaging analysis. Biophys J (2008) 94:L14-6

Pallares P, Garcia-Fernandez RA, Criado LM, Letelier CA, Esteban D, Fernandez-Toro JM, Flores JM, Gonzalez-Bulnes A. Disruption of the endothelial nitric oxide synthase gene affects ovulation, fertilization and early embryo survival in a knockout mouse model. Reproduction (2008) 136:573-9

Malengo G, Andolfo A, Sidenius N, Gratton E, Zamai M, Caiolfa VR. Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor. J Biomed Opt (2008) 13:031215

Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nat Chem Biol (2007) 3:117-25

Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke Circulation (2007) 115:1599-608

Grande-García A, Echarri A, de Rooij J, Alderson NB, Waterman-Storer CM, Valdivielso JM, del Pozo MA. Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. J Cell Biol (2007) 177:683-94

Mercader N. Early steps of paired fin development in zebrafish compared with tetrapod limb development. Dev Growth Differ (2007) 49:421-37

Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature (2006) 440:105-9

Mercader N, Fischer S, Neumann CJ Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction. Development (2006) 133:2805-15

Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet (2005) 37:391-400

Mercader N, Tanaka EM, Torres M. Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins. Development (2005) 132:4131-42

Sanchez-Morgado JM, Poynter S, Morris TH. Molecular characterization of a virulent canine coronavirus BGF strain. Virus Res (2004) 104:27-31

Haworth R, Jones S, Sanchez-Morgado J, Pilling A. Ovarian teratoma in a common marmoset (Callithrix jacchus). VET REC (2003) 153:332-3

Sanchez-Morgado JM, Haworth R, Morris TH. XY female marmoset (Callithrix jacchus). Comp Med (2003) 53:539-44

Mercader N, Leonardo E, Piedra ME, Martínez-A C, Ros MA, Torres M. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development (2000) 127:3961-70

Hagedorn L, Paratore C, Brugnoli G, Baert JL, Mercader N, Suter U, Sommer L. The Ets domain transcription factor Erm distinguishes rat satellite glia from Schwann cells and is regulated in satellite cells by neuregulin signaling. Dev Biol (2000) 219:44-58

Mercader N, Leonardo E, Azpiazu N, Serrano A, Morata G, Martínez C, Torres M. Conserved regulation of proximodistal limb axis development by Meis1/Hth. Nature (1999) 402:425-9

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