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E.g., 09/02/2025
E.g., 09/02/2025
Anagha Jagannathan, Carlos Real Jiménez, Laura Cádiz, Sofía Trigo Anca, Anabel Díaz-Guerra Priego, Miguel Fernández Tocino, Carlos Galán Arriola, Borja Ibáñez, Agustín Clemente Moragón, Sandra Gomez, Ana Devesa, Juan Rene Delgado Cornejo, Danielle Medina-Hernandez, Warren Alexander Skoza, Lucía Pilar López Palomar, Nico Hoffmann, Carlos Caballero Henares and Ángela Pollán García.
Research
4 Feb 2025

The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure

Vicente Andrés, Borja Ibáñez, Valentín Fuster, Ana García Álvarez, José Javier Fuster, Inés García Lunar, Antonio Quesada y Virginia Mass Ruiz.
Research
30 Sep 2024

A study published in The Journal of the American College of Cardiology (JACC) demonstrates that the burden and progression of silent atherosclerosis in

Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
Research
19 Sep 2024

A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk

One of the girls who participte in the study.
Research
29 Jul 2024

A study by the CNIC and Fundación SHE, supported by “la Caixa” Foundation, demonstrates that schools are a crucial environment for health promotion in children

RM cardiaca de un paciente con miocardiopatía dilatada (izquierda) y de un individuo sin cardiopatía (derecha). En el paciente con miocardiopatía dilatada el tamaño del corazón esta incrementado y su capacidad de bombeo está disminuida.
Research
19 Apr 2024

The results, published in JACC, suggest that these factors could be used to predict the risk of developing dilated cardiomyopathy and adapt strategies for patient care and disease detection in genetic carriers of the disease

Agustín Clemente-Moragón, Borja Ibáñez, Anabel Díaz-Guerra, Laura Cádiz, Carlos Galán-Arriola, Miguel Fernández-Tocino, Mónica Gómez, Rocío Villena-Gutiérrez, y Eduardo Oliver.
Research
16 Apr 2024

The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity

El Dr. Valentín Fuster con la Dra. Guiomar Mendieta
About the CNIC
10 Apr 2024

Guiomar Mendieta has been awarded the 2023 William W. Parmley Young Author Achievement Award for a paper published in JACC that is considered to an outstanding contribution in the field of atherosclerosis

Research
3 Jan 2024

A team led by scientists at the CNIC and CSIC has found that accumulation of versican in the aortas of Marfan syndrome patients triggers the activation of the nitric oxide pathway through the activation of the the protein AKT

Rafael Yuste
Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
Research
20 Nov 2023

Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough