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CNIC researchers have discovered that the heart is formed from two independent cell types that act in synchrony from the onset of gastrulation. This finding could help to better understand the origin of certain congenital heart defects and open up new opportunities in regenerative medicine and tissue bioengineering.

Dr. Mariell Jessup is Chief Science and Medical Officer of the American Heart Association

A CNIC team has developed an innovative gene therapy strategy for arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly inherited condition that particularly affects young men

Scientists at the CNIC and the University of Bern have found that heart surgery in male mice early in life creates a "memory" passed down to the next generation. Published in Circulation, the study suggests that a parental history of heart surgery should be considered when evaluating cardiovascular health in descendants.

The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure

The new project, ‘The Placenta in Maternal and Fetal Cardiovascular Health and Disease’, aims to understand how the placenta influences cardiovascular health in mothers and their children, promising improvements in the prevention and treatment of related diseases

The International Atherosclerosis Society recognizes the contributions to the understanding and treatment of atherosclerosis by the director of the National Center for Cardiovascular Research (CNIC) and president of the Mount Sinai Fuster Heart