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    E.g., 03/07/2025
    E.g., 03/07/2025
    Sarai Martínez Cano, Marcos Femenía Muiña, Elena Hernández, Vanessa Núñez, Manuel Rodrigo Tapias, Miguel Galán Burgos, Iñaki Robles, Alberto Benguria, David Sancho y Almudena Ramiro
    Research
    2 Jun 2025
    Circulation Research: CNIC scientists uncover how the immune response drives atherosclerosis—the root cause of heart attacks and strokes

    A team from the CNIC has discovered the key role of conventional type 1 dendritic cells (cDC1) in atherosclerosis and has developed an experimental therapy with immunosuppressive nanoparticles that slows the progression of the disease in animal models.
    David Sancho, Ignacio Heras-Murillo y Stefanie Wculek.
    Research
    14 Apr 2025
    Nature Communications: A type of immune cell strengthens immunotherapy and prevents tumor relapse in animal models

    A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), in collaboration with the Instituto de Investigación Biomédica de Barcelona (IRB Barcelona), has identified the most effective subtype of dendritic cell for generating immune memory in response to cancer
    Proyecto_CARMINA
    About the CNIC
    8 Apr 2025
    CARMINA: The AI model for cardiovascular research developed by the CNIC

    The system provides specialised answers to biomedical questions, ensuring data privacy by operating exclusively within the CNIC
    Macarena de Andrés Laguillo, Stefano Gambera, Sofía Sánchez Muñoz, Rui Benedito, Irene García González, Mariya Lytvyn Legin, Lourdes García Ortega, Sandra Ruiz García, Susana Ferreira da Rocha, Aroa García Cabero, Luis Diago Domingo.
    Research
    12 Dec 2024
    Nature Methods: CNIC presents iFlpMosaics, an innovative genetic toolkit for the study of gene function

    iFlpMosaics is a new technology presented in Nature Methods that allows the modification and study of gene function in mouse models, advancing research on diseases caused by somatic mutations, such as cancer and vascular malformations.
    imagen
    About the CNIC
    30 Sep 2024
    CNIC Joins the 2024 Heart Race
    ESC_Congress
    About the CNIC
    30 Aug 2024
    Several studies led by the CNIC, informed recommendations included in the newly released 2024 ESC clinical practice guidelines (CPG)
    team photo
    About the CNIC
    11 Jun 2024
    Nucleic Acids Research: A CNIC team has created an innovative tool for the reliable and efficient study of gene function

    iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function
    Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
    Research
    10 Nov 2023
    CIRCULATION RESEARCH: CNIC scientists identify the crucial role of the protein neuregulin-1 in heart development

    Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

    About the CNIC
    3 Oct 2023
    CNIC gets on the move with the Carrera del Corazón fun run
    En primer plano: Emilio Camafeita, Rui Benedito y Macarena Fernández; detrás, de izda. a dcha., Ana Dopazo, Jesús Vázquez, Alberto Benguria, Mariya Lytvyn, Severin Muhleder, Sofía Sánchez, Lourdes García.
    Research
    29 May 2023
    Nature Cardiovascular Research: Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease

    The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer