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    A 3-dimensional magnetic resonance image form a patient who has undergone an acute myocardial infarction. The heart is visible in the center of the image. Healthy (non-infarcted) cardiac muscle is indicated by asterisks, whereas arrows point to the infarcted region. MRI can reveal the extent of the area affected by inflammation after a heart attack (the yellow infarcted region marked by arrows). Serial MRI studies reveal thta this inflammatory reaction appears immediately after the infarction but then rapid
    Research
    22 Aug 2017
    Circulation: Dogma overturned: new studies into inflammation in the infarcted heart could lead to changes in therapy

    The study overturns the dogma that infarction is followed by progressive repair of the injured myocardium.
    Photo 1: The authors are holding in their hands illustrations of cells expressing different combinations of membrane and nuclei fluorescent proteins. This corresponds to the method we developed (present in the article) to differentially label cells expressing different genes (with the codes A to F). Each cell expresses a different combination of 2 genes from a pool of 6 different genes (A, B, C, D, E, and F).
    Publications
    10 Aug 2017
    Cell: CNIC Scientists develop new methods for analyzing gene function

    The study, published in Cell, will allow any researcher to induce multispectral genetic mosaics in vertebrate research models such as mice and zebrafish
    The CNIC research team. From left to right: Andrés Hidalgo, David Sancho, Sarai Martínez-Cano, Salvador Iborra, Elena Priego, Michel Enamorado, and Juan Antonio Quintana.
    Research
    17 Jul 2017
    `'Nature Comunications': Scientists Find the Key to Improved Cancer Immunotherapy

    The study, published in Nature Communications, demonstrates that tissue-resident and circulating memory T cells cooperate in anti-tumor immunity
    About the CNIC
    1 Jun 2017
    Dr. Borja Ibáñez awarded the XII Banco Sabadell Foundation Award for Biomedical Research

    Dr. Ibáñez, Director of Clinical Research at the CNIC, has received an award for his contribution to the fight against cardiovascular diseases
    The Commissioner of Health and Food Safety of the European Commission, Vytenis Andriukaitis, during his visit at CNIC.
    About the CNIC
    3 May 2017
    Health and Food Safety Commissioner from the European Commission visits CNIC

    The Health and Food Safety Commissioner from the European Commission, Vytenis Andriukaitis, visited Carlos III National Centre of Cardiovascular Research (CNIC)
    Research
    10 Jan 2017
    Nature Medicine: Inhibition of a specific protein prevents and reverses aortic aneurysm in models of Marfan syndrome and similar diseases

    The findings, published in Nature Medicine, suggest a major potential for NOS2 inhibitors in the treatment of thoracic aortic aneurysa
    Científicos del grupo de Inmunobiología del CNIC implicados en la publicación. De izquierda a derecha, arriba: Carlos del Fresno, Salvador Iborra, David Sancho, Fran Cueto; abajo: Michel Enamorado, María Martínez-López, Ruth Conde-Garrosa y Sofía Chayeb Khouili
    Research
    28 Sep 2016
    Immunity: CNIC Investigators Identify Ways to Improve Vaccine Design

    The study, published in the journal Immunity, identifies factors necessary for improving vaccines to induce long-duration cellular immunity in barrier tissues such as skin and mucous membranes
    Nestin+ cells in an atherosclerotic plaque (yellow and red) in the brachial artery of an adult mouse. The layer of muscle cells (green) delimits the vessel lumen
    Research
    8 Sep 2016
    Nature Communications: Identify a new mechanism involved in atherosclerosis

    The study, published in Nature Communications, reveals these cells as a possible target for cardiovascular cell therapy
    Polypill
    Research
    23 Aug 2016
    JACC: MINERVA results demonstrate full adherence to guideline-recommended therapies associated with lower rate of a second major cardiovascular event and cost savings

    Journal of the American College of Cardiology (JACC) Publishes Data Assessing the Impact of Medication Adherence on Long-term Cardiovascular Outcomes and Cost
    Jesús Mª Vázquez Cobos, Enrique Calvo, Rebeca Acín Pérez, José Antonio Enríquez, Ana Victoria Lechuga-Vieco, Ignacio Flores, Carlos Torroja, Fátima Sánchez Cabo, Jesús Ruiz-Cabello y Andrés González Guerra.
    Research
    7 Jul 2016
    Nature: The interaction between our two genomes, nuclear and mitochondrial, is the key to healthy aging

    The study, published in Nature, provides information with important implications for mitochondrial donation therapies, which produce children with three genetic parents