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E.g., 14/06/2024
E.g., 14/06/2024
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About the CNIC
11 Jun 2024

iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function

About the CNIC
15 May 2024

Globally, cardiovascular diseases due to atherosclerosis – the build-up of plaque in arteries – are the leading cause of death. A new Danish-Spanish research collaboration aims to develop methods to detect atherosclerosis at earlier ages and encourage prevention. Denmark’s Novo Nordisk Foundation has granted up to EUR 23 million to cover the first 2.5 years of the REACT initiative. The initiative is expected to run for 8 years in total


De izquierda a derecha: Immunofluorescencia en sección de corazón de pez cebra tras criolesion mostrando células proliferativas (blanco), cardiomiocitos (rojo) núcleos celulares (azul). Imagen de Microscopia electrónica mostrando mitocondrias. Gel Blue Native mostrando bandas correspondientes a supercomplejos formados por CIII (rojo) y CIV (verde).
Research
6 May 2024

Scientists at the CNIC, CIBER, and University of Berne identify the fundamental role of a family of proteins in an essential process for cellular energy production

María Jesús Andrés, Carla Espinós (detrás), Rosa M Nevado (delante, al lado de MJA), Miguel de la Fuente, Rosa Carmona, Ana Barettino, Vicente Andrés, Pilar Gonzalo e Ignacio Benedicto.
Research
19 Apr 2024

The elimination of progerin from vascular smooth muscle cells, but not from endothelial cells, prevents the atherosclerosis associated with Hutchinson-Gilford progeria syndrome (HGPS)

Agustín Clemente-Moragón, Borja Ibáñez, Anabel Díaz-Guerra, Laura Cádiz, Carlos Galán-Arriola, Miguel Fernández-Tocino, Mónica Gómez, Rocío Villena-Gutiérrez, y Eduardo Oliver.
Research
16 Apr 2024

The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity

El Dr. Valentín Fuster con la Dra. Guiomar Mendieta
About the CNIC
10 Apr 2024

Guiomar Mendieta has been awarded the 2023 William W. Parmley Young Author Achievement Award for a paper published in JACC that is considered to an outstanding contribution in the field of atherosclerosis

Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
Research
1 Feb 2024

A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs


Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
Research
23 Jan 2024

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis

David Sancho
About the CNIC
19 Jan 2024

The ImnovAth project seeks an innovative approach to treat atherosclerosis

Ayelén M. Santamans y Guadalupe Sabio
Research
19 Jan 2024

A team led by scientists from the CNIC and CNIO has identified a potential therapeutic target that protects the heart in patients with pulmonary hypertension